Microneedle patch convenient for administrating animal vaccine and preparation method of microneedle patch

Abstract

The invention belongs to the technical field of administration equipment and particularly relates to a microneedle patch convenient for administrating animal vaccine and a preparation method of the microneedle patch. The microneedle patch comprises a soluble patch substrate and soluble microneedle bodies in array distribution on the patch substrate, wherein the microneedle bodies carry a targeted medicine at the top ends. The preparation material of the microneedle bodies comprises a water soluble degradable macromolecular material. Compared with the prior art, the microneedle patch convenient for administrating animal vaccine provided by the invention does not cause fear responses of animals when a vaccine is inoculated, is easy to administrate and convenient to operate, and inoculating personnel needs not to be trained; the vaccine inoculating work can be completed by a single person, so that the efficiency is high; the animal is not marked in an extra manner when the vaccine is inoculated; the microneedle patch is used at one time, so that the probability of cross infection is avoided; the material used is biodegradable and free of medical wastes; the microneedle patch is simple and economic in preparation method, free of cold preservation or vacuum storage and the like and convenient to transport.

Description

technical field [0001] The invention belongs to the technical field of drug delivery equipment, and in particular relates to a microneedle patch which is convenient for animal vaccine drug delivery and a preparation method thereof. Background technique [0002] Vaccines are an important weapon to control an infectious disease. Animal vaccines belong to the category of veterinary biological products. Veterinary biological products are a class of substances prepared from microorganisms, parasites and their metabolites or immune response products based on the principles of immunology. Such substances are intended exclusively for the diagnosis, treatment or prevention of corresponding diseases in animals. The invention and promotion of animal vaccines can prevent and control the occurrence and prevalence of animal infectious diseases, and have made great contributions to the healthy development of animal husbandry in my country. [0003] The traditional method of administratio...

AI Technical Summary

Problems solved by technology

When injecting vaccines by traditional injection methods, there will be many problems: the pain caused by the injection will cause the animal's fear reaction, which will cause inconvenient injection; the skin and muscle damage or skin infection will be caused during the injection; the needle will break during the injection; there will be crossover. The possibility of infection; in order to avoid cross-infection needles need to be replaced, and the biological waste brought by disposable syringes causes environmental pollution and waste of resources; standardized operations require training for operators; injections generally require the cooperation of multiple people, which is inefficient; injections After completion, to avoid confusion, mark the injected animals, etc.

Due to the protection and barrier function of the stratum corneum on the skin surface, the efficiency of transdermal drug diffusion is very low, and the effectiveness data for vaccine administration is insufficient.

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