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Anti-ultraviolet radiation sun cream

A technology of anti-ultraviolet and sunscreen, which is applied in the field of skin care products to achieve the effect of improving antioxidant capacity, delaying skin photoaging, and accelerating skin removal

Active Publication Date: 2015-05-20
广东密尚生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no literature reporting the biological activity of this kind of compounds in the prevention and treatment of skin damage caused by ultraviolet rays after topical application

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1: the preparation of DZJB-13 cream

[0017] Prescription: vitamin E 3g, methyl silicone oil 50g, liquid paraffin 80g, beeswax 7.5g, 1-hexadecanol 40g, stearic acid 50g, glyceryl monostearate 20g, DZJB-13 15g, glycerin 100g, sulfurous acid Sodium hydrogen 3g, ethylparaben 1g, sodium lauryl sulfate 5g, and distilled water were added to make the total amount 1000g.

[0018] Preparation Process:

[0019] (1) Mix glycerin with an appropriate amount of distilled water, and when heated to about 70°C, add sodium bisulfite, ethylparaben, and sodium lauryl sulfate, and stir until dissolved to form a water phase.

[0020] (2) Take methyl silicone oil, liquid paraffin, beeswax, 1-hexadecanol, glyceryl monostearate, stearic acid, heat and melt, when the temperature reaches about 70°C, add vitamin E, DZJB-13 in turn , to make the oil phase.

[0021] (3) Slowly add the oil phase into the water phase under continuous stirring to emulsify, stir until it coagulates, and th...

Embodiment 2

[0025] Example 2: Experimental research on the prevention and treatment of DZJB-13 cream on mouse skin photoaging model

[0026] Select 36 Kunming healthy mice, weighing 20-25g, female, and randomly divide them into the following three groups: normal control group, model control group and DZJB-13 group, 12 in each group. The back hair of the mice was shaved, with an area of ​​2cm×2cm. In addition to the normal control group, it and the two groups of mice were exposed to simulated sunlight under ultraviolet lamps (UVA and UVB ultraviolet lamps were produced by Hefei Saifan Experimental Equipment Co., Ltd., models UVA-340 and UVB-313), and the irradiation distance was 50cm. , 1h / d, 5 times a week for 8 consecutive weeks. Before 20 minutes of ultraviolet irradiation, the mice in the DZJB-13 group evenly applied the DZJB-13 cream prepared in Example 1 to the depilated area, and both the normal control group and the model control group applied the blank cream prepared in Comparati...

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PUM

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Abstract

The invention discloses an anti-ultraviolet radiation sun cream, which comprises the following active components: (7-acetoxyl-2-(acetoxyl methyl)-1-((4-acetoxyl benzene) acetenyl)-9H-fluorene-9,9-di-substituted) bi(4,1-phenylene) glacial acetic acid or a derivative thereof. The antioxidant capacity of ultraviolet-radiated skin can be improved; removal of oxygen free radicals can be accelerated; amino acid metabolism of skin tissues after ultraviolet radiation is adjusted; and the content of skin collagen is increased, s that the anti-ultraviolet radiation sun cream plays a protecting role in the ultraviolet-radiated skin, and skin photoaging is delayed.

Description

technical field [0001] The invention belongs to the technical field of skin care products, and in particular relates to an anti-ultraviolet radiation sunscreen. Background technique [0002] As the ozone layer becomes thinner, more and more ultraviolet rays reach the ground. The intensity of ultraviolet rays contained in sunlight is very high. In summer, when the sun shines directly on the skin, ultraviolet rays can penetrate the surface of the skin most easily. Ultraviolet rays can not only produce melanin, darken the skin, but also cause skin aging. When the skin is exposed to excessive ultraviolet rays , will damage the epidermal cells. Most of the damage caused by sunlight is caused by ultraviolet radiation with a wavelength of 200 to 400nm. Among them, UVC with a wavelength of less than 290nm is basically absorbed by the ozone layer and cannot reach the ground; UVB with a wavelength of 290 to 320nm can cause burns and skin pigmentation; UVA with a wavelength of 320 to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/92A61K8/37A61Q17/04
Inventor 李健
Owner 广东密尚生物科技有限公司
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