Nano-hydroxyapatite ceramic and preparation method thereof

Abstract

The invention relates to a nano-hydroxyapatite ceramic and a preparation method thereof and belongs to the technical field of ceramic processing. The nano-hydroxyapatite ceramic is prepared from the following components in parts by weight: 20-50 parts of hydroxyapatite, 40-60 parts of Al2O3, 10-20 parts of CaO, 1-10 parts of ZrO2, 1-10 parts of Y2O3 and 1-10 parts of CaF2. The preparation method of the nano-hydroxyapatite ceramic comprises the following steps of: matching the components according to a proportion, adding an alcohol solution, mixing uniformly, kneading, evaporating a solvent in a water bath at the temperature of 80 DEG C, heating to expand in a drying oven at the temperature of 70-90 DEG C, molding, putting the molded blank into a muffle furnace, increasing the temperature of the muffle furnace to 1,000-1,200 DEG C slowly, treating the blank for 8-10 hours, cooling, and taking out of the muffle furnace to obtain a finished product of the nano-hydroxyapatite ceramic. The nano-hydroxyapatite ceramic provided by the invention is a three-dimensional nano-porous expanded product, has the porosity of 90% or higher and is suitable for scaffold materials and bone repair materials in the bone tissue engineering.

Description

technical field [0001] The invention relates to a ceramic and a preparation method thereof, in particular to a nano-hydroxyapatite ceramic material and a preparation method thereof, belonging to the technical field of ceramic processing. Background technique [0002] The main reasons why people have been keen on bioceramic hard tissue research for nearly half a century are: (1) the surgical trauma and possible complications of autologous bone transplantation; (2) the potential risk of disease transmission in allogeneic bone transplantation; Tissues can be organically combined with some calcium-containing bioceramics; (4) The development of bioceramics preparation technology. Hydroxyapatite is the main inorganic component of human bones. It is a kind of bioactive material with good biocompatibility. After implanted in bone tissue, it can form a strong chemical bond with bone on the interface and has bone conduction. And osteoinductivity, so it is one of the key substances in...

AI Technical Summary

Problems solved by technology

[0005] 201310148908.2 discloses a porous nano-ceramic made of hydroxyapatite nano-rods or sheets and its preparation method. Porous nano-ceramics constructed by sheets; but this method has high requirements for equipment, so that the patent has problems such as high one-time investment and difficulty in reducing product costs; the present invention uses hydroxyapatite, Al 2 o 3 , CaO, ZrO 2 , Y 2 o 3 , CaF 2 etc. as raw materials, the prepared nano-hydroxyapatite ceramics have high biological activity and improved its degradability, the preparation method is simple, the reproducibility is high, and it can be produced on a large scale