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Traditional Chinese medicine composition for treating fatty liver combined with hyperlipidemia and preparation method of traditional Chinese medicine composition

A technology for hyperlipidemia and a composition, applied in the field of medicine, can solve the problems of elevated alanine aminotransferase, aggravate fatty liver disease, damage liver function and the like, achieve good fatty liver combined with hyperlipidemia, simple preparation, and easily available raw materials Effect

Active Publication Date: 2015-04-08
阿南达
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, Western medicine is not effective in the treatment of fatty liver complicated with hyperlipidemia. This is because improper use of lipid-lowering drugs will cause alanine aminotransferase to increase, which will damage liver function, and even promote lipid deposition in the blood in the liver. , aggravate the condition of fatty liver, and Chinese medicine is a traditional treasure of our country, which has accumulated rich clinical experience and treatment theory in the treatment of fatty liver

Method used

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  • Traditional Chinese medicine composition for treating fatty liver combined with hyperlipidemia and preparation method of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1 Chinese medicine composition mixture of the present invention

[0015] Prescription: Polygonum cuspidatum 15g, Alisma 6g, cassia seed 10g, hawthorn 10g, turmeric 10g, lotus leaf 20g, salvia miltiorrhiza 15g, Polygonum multiflorum 13g, grape seed 5g, pinellia 5g, tangerine peel 10g, digupi 12g, calamus 8g, Corydalis 9g, red peony 11g, astragalus 7g, licorice 10g.

[0016] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 30 minutes, decoct twice for 2 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 Extraction, the relative density is the test result at 60 degrees Celsius, add ethanol to alcohol content of 75% (v / v), let it stand for 24 hours, take the supernatant, reclaim the ethanol concentration, add water to 1000ml, stir Mix evenly, sub-package, and sterilize with circulat...

Embodiment 2

[0017] Embodiment 2 Chinese medicine composition tablet of the present invention

[0018] Prescription: Polygonum cuspidatum 150g, Alisma 60g, cassia seed 100g, hawthorn 100g, turmeric 100g, lotus leaf 200g, salvia miltiorrhiza 150g, Polygonum multiflorum 130g, grape seed 50g, Pinellia 50g, tangerine peel 100g, Digupi 120g, Shichangpu 80g, Corydalis Corydalis 90g, Radix Paeoniae Rubra 110g, Radix Astragali 70g, Licorice Root 100g.

[0019] Preparation method: Take each medicinal material of the above weight components, add water 10 times the total weight of the medicinal materials, soak for 60 minutes, decoct once, 1 hour each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.25 The extractum, the relative density is the detection result at 60 degrees Celsius, adding ethanol until the alcohol content is 80% (v / v), standing for 24 hours, taking the supernatant, reclaiming the ethanol to concentrate, vacuum drying,...

Embodiment 3

[0020] Embodiment 3 Chinese medicine composition capsule of the present invention

[0021] Prescription: Polygonum cuspidatum 1500g, Alisma 600g, cassia seed 1000g, hawthorn 1000g, turmeric 1000g, lotus leaf 2000g, salvia miltiorrhiza 1500g, Polygonum multiflorum 1300g, grape seed 500g, Pinellia 500g, tangerine peel 1000g, Digupi 1200g, Shichangpu 800g, Corydalis 900g, Radix Paeoniae Rubra 1100g, Radix Astragali 700g, Licorice Root 1000g.

[0022] Preparation method: Take the medicinal materials of the above weight components, add water 8 times the total weight of the medicinal materials, soak for 45 minutes, decoct 4 times for 1.5 hours each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.2 The extract, the relative density is the test result at 60 degrees Celsius, adding ethanol to the alcohol content of 90% (v / v), standing for 24 hours, taking the supernatant, reclaiming the ethanol to concentrate, vacuum dr...

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Abstract

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating fatty liver combined with hyperlipidemia as well as a preparation method and an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition for treating fatty liver combined with hyperlipidemia provided by the invention is prepared from the following components in parts by weight: 15 parts of polygonum cuspidatum, 6 parts of rhizoma alismatis, 10 parts of semen cassia, 10 parts of hawthorn, 10 parts of radix curcuma, 20 parts of lotus leaves, 15 parts of salviae miltiorrhizae, 13 parts of processed polygonum multiflorum, 5 parts of grape seeds, 5 parts of pinellia ternate, 10 parts of pericarpium citri reticulatae, 12 parts of cortex lycii radicis, 8 parts of acorus tatarinowii, 9 parts of rhizoma corydalis, 11 parts of red peony root, 7 parts of astragalus membranaceus and 10 parts of liquorice. The traditional Chinese medicine composition has a good treatment effect on fatty liver combined with hyperlipidemia, and has significant promotional value.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition for treating fatty liver complicated with hyperlipidemia, a preparation method and application thereof. Background technique [0002] Fatty liver refers to the pathological changes caused by excessive accumulation of fat in liver cells due to various reasons. Fatty liver disease is a serious threat to the health of Chinese people, becoming the second largest liver disease after viral hepatitis, and has been recognized as a common cause of hidden cirrhosis. Fatty liver is a common clinical phenomenon rather than an independent disease. Its clinical manifestations are asymptomatic in mild cases, and violent in severe cases. Generally speaking, fatty liver is a reversible disease, early diagnosis and timely treatment can often return to normal. The total amount of fat in the liver of normal people accounts for about 5% of the liver we...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/16A61P3/06
CPCA61K9/0095A61K9/20A61K9/48A61K36/481A61K36/482A61K36/484A61K36/537A61K36/62A61K36/65A61K36/66A61K36/704A61K36/71A61K36/734A61K36/752A61K36/815A61K36/87A61K36/884A61K36/888A61K36/8888A61K36/9066A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 李建美
Owner 阿南达
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