Medical hemostatic sponge and preparation method

Abstract

The invention discloses a medical hemostatic sponge and a preparation method. The sponge is a milk-white loose and porous sponge material composed of bletilla mannan extracted from the dry tubers of orchid bletilla, wherein the essential of the preparation method is that mannan in bletilla is extracted out by water extraction and alcohol precipitation processes at first, and then is prepared into the loose and porous sponge material by a vacuum freeze-drying technology. The sponge is wide in material source, low in cost, non-immunogenicity, high in adhesion speed for wound surface, high in adhesion firmness, remarkable in physical hemostatic effect, soft in performance, capable of being used without pre-treatment, extremely high in cost performance, and capable of replacing the existing gelatine hemostatic sponge.

Description

technical field [0001] The invention relates to a medical hemostatic sponge, in particular to a bletilla polysaccharide hemostatic sponge made from the extract of the traditional Chinese medicine bletilla and a preparation method thereof. Background technique [0002] Hemostasis is the most basic method in the operation of various departments in the hospital. Hemostasis plays a considerable role in the success of the operation and the safety of the patient. For the operation of liver, spleen, brain, kidney and other solid organs, the operation of vascular lesions and tumors, other operations such as tooth extraction, and patients with abnormal blood coagulation function, relying solely on mechanical hemostasis Methods such as ligation, suture, electrocautery, etc. are far from enough, and must rely on the use of auxiliary hemostatic materials. At present, most of the auxiliary hemostatic materials commonly used in domestic clinical operations are gelatin hemostatic sponges....

AI Technical Summary

Problems solved by technology

Although the gelatin hemostatic sponge has a certain auxiliary hemostatic effect, it is still not ideal, which is manifested in the following aspects: (1) its component is mainly protein-polyamino acid, which has potential immunogenicity and is not suitable for allergies. Physical constitution patients; (2) The rate of polyamino acid dissociation in wound exudate is relatively slow, that is, the combination speed of gelatin and wound exudate is slow, resulting in slow adhesion to the wound, and it takes a long time to compress. (3) The adhesion fastness of polyamino acid to the wound surface is poor, and it is easy to cause shedding, especially for the incision wound of the lost shape; (4) Its mechanical properties are poor, its texture is brittle, and it is easy to break Cracks, easy to break, and poor adhesion to the wound; (5) It generally needs to be soaked and rubbed with physiological saline before use, which is not very convenient to use

The price of similar products sold in foreign markets is extremely high, such as the hemostatic sponge with the brand name TachoComb, each product is only 1cm 2 , thickness 0.5cm, each piece can only be used for 0.8cm 2 Left and right wounds, the applicable wounds are limited, but the price of each piece is more than 400 yuan, and its performance-price ratio is too low, so it is not suitable for domestic patients.