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Drug combination and purpose for preventing and curing osteoporosis

A technology for osteoporosis and composition, which is applied in the fields of medicine and food to achieve the effects of preventing and treating osteoporosis, being convenient to take, and having no toxic and side effects.

Inactive Publication Date: 2015-01-07
CHANGCHUN UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Before the application of the present invention, it was not found that the composition composed of total flavonoids of hops, deer bone glycopeptide, deer bone active calcium, and Ligustrum lucidum extract can prevent and treat osteoporosis.

Method used

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  • Drug combination and purpose for preventing and curing osteoporosis
  • Drug combination and purpose for preventing and curing osteoporosis
  • Drug combination and purpose for preventing and curing osteoporosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Example 1 Extraction preparation of the composition

[0052] (1) Hops were reflux extracted twice with 60% ethanol, 2 o'clock each time, filtered, the filtrate recovered ethanol, added water to contain 0.6g of crude drug per ml, passed through the pre-treated AB-8 macroporous resin column, first deionized Elute with water for 4 times the column volume, then use 70% ethanol to elute for 4 times the column volume, collect the ethanol eluate, recover the ethanol, and dry to obtain the total flavonoids of hops;

[0053] (2) Wash the deer bone with clean water, crush it into a coarse powder, use 5 times the amount of deionized water in an autoclave for high-pressure extraction for 3 hours, filter, add 4 times the amount of deionized water to the filter residue and continue to extract until the deer bone is loose and brittle filter, combine the two filtrates, let cool, degrease, concentrate, the concentrate is precipitated with 5 times the amount of ethanol, filtered, and...

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Abstract

The invention discloses a natural drug combination for assisting in preventing and curing osteoporosis. The drug combination is characterized by comprising hop general flavone, ox bone glycopeptides, ox bone active calcium and glossy privet fruit extractive. The combination takes kidney tonifying, muscle and bone strengthening, qi replenishing to invigorate the spleen and blood activating and liver coordinating in Chinese medicine as a base point, combines different action mechanisms, such as supplementing calcium supplementation, supplementation of vitamin D and activated products thereof, supplementation of collagen and gonadal hormone concentration adjustment, utilizes the synergistic effect of all the constituents, achieves the effect of preventing and curing osteoporosis, can be prepared into oral preparation, such as hard capsules, soft capsules, tablets, granules, powders, pills, tea bags and medicinal liquor, and can be applied to Chinese patent medicine or health food.

Description

technical field [0001] The invention relates to a natural medicine composition helpful for preventing and treating osteoporosis, which belongs to the fields of medicine and food. Background technique [0002] Osteoporosis (OP) is a systemic bone metabolic disease characterized by low bone mass and microarchitectural destruction of bone tissue, leading to increased bone fragility and susceptibility to fracture. The disease is common in the elderly, but it can occur at any age. Osteoporosis can be divided into primary and secondary types. Primary osteoporosis refers to other diseases that do not cause the disease; secondary osteoporosis refers to the reduction of bone tissue caused by various systemic or endocrine and metabolic diseases. With the aging of the social population, the incidence of osteoporosis is increasing day by day, which brings great suffering to patients and a heavy burden on families and society. As important as the treatment of hyperlipidemia to prevent...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/638A23L1/29A61P19/10A61K35/32A23L33/00
CPCA23V2002/00A61K35/32A61K36/60A61K36/638A61K2300/00A23V2200/306A23V2250/204A23V2250/21
Inventor 赵全成南敏伦赵昱玮赫玉芳马吉胜吕娜何忠梅
Owner CHANGCHUN UNIV OF TECH
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