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Traditional Chinese medicine for treating edema syndrome due to yang deficiency in chronic obstructive emphysema syndrome disease, and preparation method thereof

A chronic obstructive, yang-deficiency water flooding technology, applied in the field of pharmacy, can solve problems such as protease-anti-protease balance imbalance, antibiotic resistance, and unsatisfactory clinical efficacy, so as to achieve strong pertinence and keep the airway unobstructed , Improve the effect of gas exchange function

Inactive Publication Date: 2014-12-10
王岷
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] 2. Air pollution
[0009] 3. Infection
[0011] 4. Protease-antiprotease imbalance
However, the course of treatment is long, long-term large-scale use of antibiotics is prone to drug resistance, many adverse reactions, the disease is likely to be protracted, and the clinical curative effect is not satisfactory, causing certain economic burden and mental pressure to patients and their families, and significantly reducing the quality of life.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0095] Wherein, when the dosage form of traditional Chinese medicine is spray, its preparation method comprises the following steps:

[0096] a. Weigh all raw medicinal materials according to the stated ratio, add water 3-5 times the weight of the obtained mixture and soak for 3-10 hours, after boiling with high fire, use slow fire to fry slowly for 30-50 minutes until the dosage of the medicinal liquid is 100-300ml, decoct 3 times, combine the decoction and filter, heat the filtrate to obtain extract 1, and use the dregs for later use;

[0097] b. Soak the medicinal dregs in step a with 60-90% ethanol for 0.5-1.5 hours, extract twice, each time for 1-2 hours, combine the extracts, filter with 80-160 mesh, and centrifuge at 6000-10000 rpm The final supernatant is ultrafiltered through an ultrafiltration column with a cut-off molecular weight of 5000-10000, and the ultrafiltrate is concentrated under reduced pressure to obtain an extract 2 with a relative density of 1.35 at 80°...

Embodiment 1

[0110] Embodiment 1 Spray of the present invention

[0111] Take 27g of cassia twigs, 15g of fenugreek, 17g of scallion, 36g of geese, 28g of yuliren, 10g of morning glory, 22g of walnut kernel, 8g of inula, 14g of white front, 30g of poria cocos, 25g of coix seed, 9g of araceae, 16g of corn silk . Yuhua 18g, Hedyotis diffusa 27g, Commelina 26g, Psoralen 9g and Gecko 29g.

[0112] Its preparation method comprises the following steps:

[0113] a. Weigh all the raw medicinal materials according to the stated ratio, add water 3 times the mass of the obtained mixture and soak for 10 hours, after boiling with strong fire, switch to slow fire for 30 minutes until the dosage of the medicinal liquid is 300ml, decoct 3 times , the combined decoction liquid is filtered, and the filtrate is heated to obtain extract 1, and the dregs are for subsequent use;

[0114] b. soak the dregs of step a with 60% ethanol for 1.5 hours, extract twice, each time for 1 hour, combine the extracts, fil...

Embodiment 2

[0117] Embodiment 2 lozenge of the present invention

[0118] Take 40g of cassia twigs, 22g of fenugreek, 24g of scallions, 24g of geese not eating grass, 23g of Yu Liren, 7g of morning glory, 15g of walnut kernels, 5g of inula inula, 25g of white front, 34g of poria cocos, 15g of coix seed, 7g of araceae, and 30g of corn silk . 25g of Yuhua, 15g of Hedyotis diffusa, 32g of Commelina, 16g of psoralen and 33g of Gecko.

[0119] Its preparation method comprises the following steps:

[0120] In the first step, mix cinnamon twigs, fenugreek, scallions, goose not eating grass, Yu Liren, morning glory, walnut kernels and inula inula, and soak them in ethanol with an alcohol concentration of 95% that is 5 times the mass of the obtained mixture , extract after heating and reflux for 3 hours, and filter; soak the filter residue with ethanol with an alcohol concentration of 90% that is twice the mass of the obtained mixture again, extract after heating and reflux for 1 hour, and filte...

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Abstract

The invention discloses traditional Chinese medicine for treating edema syndrome due to yang deficiency in chronic obstructive emphysema syndrome diseases, and a preparation method thereof. The traditional Chinese medicine comprises the following raw medicinal materials: cassia twig, herba elsholtziae, fistular onion stalk, centipeda minima, bunge cherry seed, semen pharbitidis, semen juglandis, inula japonica, willowleaf swallowwort rhizome, poria cocos, semen coicis, rhizoma arisaematis, corn stigma, euphorbia helioscopia, radix asteris, radix aconiti carmichaeli, rhizoma zingiberis, cloves, pepper, pericarpium citri reticulatae, agilawood, fingered citron, fructus citri, sword bean, Chinese yam, sea buckthorn, ludwigia palustris, textile screw pine flower, oldenlandia diffusa, dayflower, fructus psoraleae and gecko. The traditional Chinese medicine has the benefits that the traditional Chinese medicine has the efficacies of warming yang, drinking and inducing diuresis, and improving a lung and bronchial tissue gas exchange function; the phlegm elimination is promoted, a respiratory muscle function is improved, the respiratory tract non-obstruction is kept, and a cardio-pulmonary function is improved; the traditional Chinese medicine has the advantages and the characteristics that pure natural traditional Chinese medicinal materials are selected, medicine resources are wide, the effects of safety and effectiveness are realized, the price is low, patients easily accept, the life quality of patients can be obviously improved, and the clinical marketing can be performed.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating chronic obstructive emphysema with yang deficiency and flooding syndrome and a preparation method thereof. [0002] Background technique [0003] Obstructive emphysema is chronic obstructive pulmonary emphysema, strictly speaking emphysema is not a disease in its own right but an anatomical / structural term that results from the development of chronic bronchitis or other chronic lung disease. Mainly the expansion and hyperinflation of the distal part of the terminal bronchi of lung tissue, including respiratory bronchioles, alveolar ducts, alveolar sacs, and alveoli, resulting in decreased elasticity and increased volume of lung tissue. Because of its slow onset and long course, it is called chronic obstructive emphysema. In my country, the incidence rate is about 0.6% to 4.3%. [0004] Etiology [0005] 1. Smoking [0006] Cigaret...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P11/00A61K35/56
Inventor 王岷王珺陈文靖刘磊姜琪娜刘俊丽
Owner 王岷
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