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A kind of preparation method of kidney-tonifying traditional Chinese medicine oral liquid

A technology for traditional Chinese medicine oral liquid and kidney-tonifying liquid is applied in the field of preparation of kidney-tonifying traditional Chinese medicine oral liquid, which can solve the problems of large consumption of ethanol, difficult separation of solid and liquid, poor clarity, etc. Effects of Solvent Residue Problems

Active Publication Date: 2018-04-13
JIUZHITANG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the original process, the extracts of medicinal materials such as Astragalus membranaceus and Rehmannia glutinosa were refined using alcohol precipitation followed by filtration and separation. Not only were macromolecular substances such as tannin not removed but active ingredients such as polysaccharides were removed, the production cycle was long and the ethanol consumption The dosage is large, the cost is high, and there are hidden dangers in safe production
[0004] In addition, the original preparation method of Bushen Tonifying Oral Liquid also has the following problems: the viscosity of the medicinal liquid is high, the solid-liquid is difficult to separate, and the liquid preparation prepared from this medicinal liquid has precipitation after being placed for a long time, and the clarity is not good.

Method used

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  • A kind of preparation method of kidney-tonifying traditional Chinese medicine oral liquid
  • A kind of preparation method of kidney-tonifying traditional Chinese medicine oral liquid
  • A kind of preparation method of kidney-tonifying traditional Chinese medicine oral liquid

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Effect test

Embodiment 1

[0094] prescription:

[0095] Ginseng 120g, deer antler (crisp) 120g, bullwhip (crisp) 60g

[0096] Dog Whip (Crisp) 60g Astragalus 360g Angelica 120g

[0097] Cistanche 40g Actinolite (calcined) 120g Wolfberry 720g

[0098] Eucommia 240g Aconite (made) 180g Cuscuta 240g

[0099] Rehmannia glutinosa 240g Epimedium 480g Leek seeds 120g

[0100] Preparation method:

[0101] 1) Crush ginseng and deer antler into coarse powder, add 60% ethanol to heat and reflux extraction for 3 times, each time for 1 hour, filter, and recover the ethanol from the filtrate for later use.

[0102] 2) Astragalus and other thirteen medicinal materials and the dregs of step 1) are added to decoct 3 times, the first time is 10 times the amount of water, decocting for 3 hours, the second time is 8 times the amount of water, decocting for 2 hours, and the second time is 8 times the amount of water, decocting for 2 hours, Three times 4 times the amount of water, decoct for 1 hour, combine the decocti...

Embodiment 2

[0107] Prescription: same as the prescription of embodiment 1.

[0108] Preparation method: 1) Crush ginseng and deer antler into coarse powder, add 90% ethanol to heat and reflux to extract twice, each time for 2 hours, filter, and recover the ethanol from the filtrate for later use.

[0109] 2) Astragalus and other thirteen medicinal materials and the dregs of step 1) are added to decoct 3 times, the first time is 9 times the amount of water, decocting for 3 hours, the second time is 6 times the amount of water, decocting for 2 hours, and the second time is 6 times the amount of water, decocting for 2 hours. Three times 4 times the amount of water, decocted for 2 hours, combined decoction, filtered through gauze, the filtrate was concentrated to a clear paste with a relative density of 1.04-1.06 (measured at 60°C), let cool to 70°C,

[0110] 3) Step 2) Add 1% chitosan acetic acid solution to the obtained clear paste, the amount of chitosan acetic acid solution added is 5.5% ...

Embodiment 3

[0114] Prescription: same as the prescription of embodiment 1.

[0115] Preparation method: 1) Crush ginseng and deer antler into coarse powder, add 70% ethanol to heat and reflux to extract twice, each time for 2 hours, filter, and recover ethanol from the filtrate for later use.

[0116] 2) Astragalus and other medicines such as thirteen medicinal materials and the dregs of step 1) are decocted twice, the first time is 8 times the amount of water, decocting for 2 hours, the second time is 6 times the amount of water, decocting for 2 hours, Combine the decoctions, filter the plate and frame, concentrate the filtrate to a clear paste with a relative density of 1.04-1.06 (measured at 60°C), let cool to 65°C,

[0117] 3) Step 2) Add 1% chitosan acetic acid solution to the obtained clear paste, the amount of chitosan acetic acid solution added is 5.0% of the clear paste weight, stir well, cool to room temperature, let stand for 24 hours, horizontal automatic centrifuge Centrifug...

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Abstract

The invention discloses a preparation method of a traditional Chinese medicine oral liquid for invigorating the kidney. The method comprises: extracting crude drugs such as bullwhip and astragalus with water, adding a flocculation clarifier to the extract, filtering and separating the obtained liquid through a ceramic membrane , the filtrate is mixed with alcohol extracts of ginseng and deer antler, and suitable auxiliary materials are added to make oral liquid. On the one hand, the method of the present invention reduces the loss of active ingredients and the decomposition and changes of some ingredients, and improves the utilization rate of medicinal materials; Macromolecular substances, but also retain the active ingredients such as polysaccharides. Compared with the traditional alcohol precipitation process, it can shorten the production cycle, save energy and reduce emissions, reduce costs and increase production safety.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a preparation method of a traditional Chinese medicine oral liquid for invigorating the kidney. Background technique [0002] Tonifying kidney essence oral liquid is composed of ginseng, antler (crisp), bullwhip (crisp), dog whip (crisp), astragalus, angelica, cistanche, actinolite (calcined), medlar, eucommia, aconite (made), dodder The traditional Chinese medicine preparation for invigorating the kidney, composed of Rehmannia glutinosa, Rehmannia glutinosa, Epimedium, and leek seeds, is recorded in the National Compilation of Chinese Patent Medicine Standards Internal Medicine Kidney System Subvolume. For deficiency of qi and blood, deficiency of kidney qi, weak waist and knees, impotence and cold essence. [0003] In the original process, the extracts of medicinal materials such as Astragalus membranaceus and Rehmannia glutinosa were ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8962A61K9/08A61P13/12A61K33/26A61K35/32A61K35/48
Inventor 朱丽谷陟欣袁莉颜冬兰黄胜欧金秀刘淑妦郗瑞云
Owner JIUZHITANG
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