Plaster for promoting qi and relaxing bowels and preparation method of plaster

Abstract

The invention discloses a plaster for promoting qi and relaxing bowels and a preparation method of the plaster. The effective components of the plaster include a traditional Chinese medicine micro-powder, a heating material and an appropriate substrate. The traditional Chinese medicine micro-powder is mainly prepared from 10%-15% of pine spike powder, 25%-40% of rhubarb, 10%-15% of fructus aurantii immaturus, 10%-15% of polygonum multiflorum, 5%-10% of peach kernel, 5%-10% of hemp, 8%-12% of liquorice and 5-10% of mint; the heating material is composed of iron powder, activated carbon and sodium chloride in the ratio of 5: 1: 1. The preparation method of the plaster comprises evenly mixing the traditional Chinese medicine micro-powder, the heating material and a Cataplasm substrate in the ratio of 1: 1: 4 by stirring, coating, slitting and packaging in vacuum, thereby obtaining plasters. The plaster for promoting qi and relaxing bowels has lasting medicine release effect and high slow release effect; the plaster has excellent curative effect on promoting qi and relaxing bowels and treating diseases such as habitual constipation, postoperative intestinal tympanites and abdominal distention.

Description

technical field [0001] The invention belongs to a traditional Chinese medicine patch and a preparation method thereof, in particular to a qi-relieving patch and a preparation method for treating diseases such as constipation, wrist and abdomen fullness, postoperative flatulence and the like. Background technique [0002] Plaster refers to the external dosage form that dissolves or mixes the drug in a natural or synthetic polymer material matrix, spreads it on the back material, and sticks it on the skin. Among them, the patch based on water-soluble polymer material is called poultice. Catalyst is a kind of external plaster, which has a long history of application in Japan. It is a patch made of medicinal material extracts, medicinal materials or / and chemical drugs mixed with a suitable hydrophilic matrix, and then coated on the backing material. , Anti-mucosal membrane (isolating film on the surface of the paste). It has a large drug loading capacity, strong moisture rete...

AI Technical Summary

Problems solved by technology

Its shortcomings can be summarized as follows: 1) Due to the use of chemical glue as the substrate, although the problem of poor ventilation is solved by punching holes, the allergy rate is still very high

2) The drug content is low, the coating is only 0.1mm, and most of them only rely on the addition of western medicine analgesic ingredients to temporarily play an analgesic effect; 3) The molecular structure of the colloid is tight, and the drug is wrapped inside, and the active ingredients of the drug cannot penetrate at all, and can only play a role. 4) Using gasoline as a solvent, the processing is dangerous and polluting

[0005] Normal temperature pressure-sensitive adhesive plaster, the process is to add traditional Chinese medicine micropowder into the normal temperature pressure-sensitive adhesive and stir it, apply it on the spunlace cloth or non-woven fabric with the same process as industrial tape, and then use anti-adhesive paper to adhere In the above, due to the low production cost, energy saving, and good-looking appearance, it is adopted by many manufacturers. Compared with adhesive plaster, it only improves the production process and spare materials, and only pays attention to its surface, but does not fundamentally solve the problem. question

The dosage form has the following disadvantages: 1) The drug content is low, and the coating is no more than 0.1mm like an adhesive plaster; 2) The temporary pain relief effect is achieved by adding western medicine ingredients; 3) The viscosity is not easy to control, not sticky. It just can't be peeled off, it's unstable

However, from the point of view of transdermal administration, there are still the following deficiencies: 1) The molecular structure of the colloid is tight, and the traditional Chinese medicine cannot penetrate at all, and only relies on the ingredients of western medicine for temporary analgesic effect.

2) It feels elastic, but it definitely does not have the function of moisturizing. It just thickens the thickness of the coating, which does not have the effect of moisturizing and controlled release at all.

[0010] Moxibustion Plaster is a dosage form that mixes traditional Chinese medicine powder, iron powder, and activated carbon, adds oxidants, and then packs and seals it into bags with a packaging machine. When used, the package is opened to produce an oxidation reaction with air, so as to achieve the effects of heat therapy and drug therapy. , has a certain curative effect on rheumatic bone disease, but the effect on other symptoms is not obvious

[0011] The above is the introduction and analysis of traditional Chinese plasters and new dosage forms. Each has its own characteristics, but there are certain shortcomings, which are manifested in: allergies, drug content, transdermal absorption rate, paste strength, controlled release, etc. insufficient