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Vertical rotating fluorescent molecule tomography imaging system

A technology of fluorescence molecular tomography and imaging system, which is applied in the field of vertical rotating fluorescence molecular tomography imaging system, can solve the problems such as the difficulty of converging the array LED light source, the low power of a single LED, and no fluorescence imaging system, and shorten the length of the optical fiber. , the effect of reducing the volume and reducing the radius of gyration

Active Publication Date: 2014-09-10
PEKING UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the power of a single LED is low, and the array LED has the problem that the light source is difficult to gather. There is no better fluorescent imaging system using LED array lighting as the light source.

Method used

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  • Vertical rotating fluorescent molecule tomography imaging system
  • Vertical rotating fluorescent molecule tomography imaging system
  • Vertical rotating fluorescent molecule tomography imaging system

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Embodiment Construction

[0037] Below in conjunction with accompanying drawing, through embodiment, further illustrate the present invention.

[0038] Such as figure 1 As shown, the vertical rotary fluorescence molecular tomography system of this embodiment includes: an excitation light source device 1, an optical fiber switching device, a bobbin 3, a fluorescence excitation device including a reflective excitation device 41 and a transmission excitation device 42, a fluorescent Detection device 5, rotating table 6, examination bed 7, translation table 8 and computer 9; wherein, excitation light source device 1 is fixed on the base plate 10, bobbin 3, fluorescence excitation device 4 and fluorescence detection device 5 are respectively installed through connectors On the rotary table 6; the rotary table 6 is installed on the base plate 10, and has a through hole in the middle, and rotates with the axis of the through hole as the rotation axis during imaging; the examination bed 7 is installed on the t...

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Abstract

The invention discloses a vertical rotating fluorescent molecule tomography imaging system. The imaging system comprises a light source excitation device, an optical fiber switching device, a winding reel, a fluorescence excitation device, a fluorescence detection device, a rotating table, an examination table, a horizontal moving table and a computer. The optical fiber switching device and the winding reel solve the problems of electrical connection, optical transmission and data transmission in the rotating process of an imaging platform, and meanwhile two imaging modes can be switched freely; the design of an optical path of a plane mirror is adopted in an imaging part, the rotation radius of the system is reduced, and therefore the system can be simple and compact; reflecting type two-dimensional fluorescent molecule imaging and transmission-type three-dimensional fluorescent molecule tomography imaging of 360 degrees can be achieved at the same time, the two imaging modes are integrated on the same device, and the amount of information capable of being obtained is increased; the light source excitation device, the optical fiber switching device, the fluorescence detection device and the like are designed in a modular mode, and therefore the portability and the universality are good.

Description

technical field [0001] The invention relates to the field of biomedical engineering, in particular to a vertical rotating fluorescent molecular tomography imaging system. Background technique [0002] Fluorescent molecular imaging technology is an imaging method widely used in in vivo, non-invasive and quantitative research on physiological and pathological changes of organisms at the molecular level. play an important role. According to the working mode, the fluorescent molecular imaging system can be divided into two types: planar reflective fluorescence imaging (Epi-illumination Imaging) and tomographic fluorescent molecular tomography (Fluorescence Molecular Tomography, FMT). FMT is a technology that uses the excitation light and the outgoing light information of the measured sample to reconstruct the three-dimensional distribution information of the position and concentration of specific fluorescent groups according to the diffusion and absorption properties of light. ...

Claims

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Application Information

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IPC IPC(8): A61B5/00
Inventor 任秋实翟晓晖丁翼晨李长辉
Owner PEKING UNIV
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