Anti oral Helicobacter pylori traditional Chinese medicine toothpaste

A technology of Helicobacter pylori and traditional Chinese medicine toothpaste, applied in the directions of oral care, antitumor drugs, local antibacterial agents, etc., can solve the problems of increasing drug resistance of Helicobacter pylori, recurring disease, increasing the difficulty of treatment, etc., to reduce bacterial adhesion and Aggregation, dental caries prevention, effect of wide availability

Active Publication Date: 2016-03-16
SHANGHAI LIKANG DISINFECTION HIGH TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing technology uses large doses of multiple antibiotics to kill Helicobacter pylori at the same time, which increases the drug resistance of Helicobacter pylori, easily leads to repeated attacks of the disease, and increases the difficulty of treatment
The disadvantage of the prior art is that taking large doses of antibiotics makes Helicobacter pylori resistant
Its shortcoming is: 1. Toothpaste, chewing gum, buccal tablet, liniment, spray, mouthwash, gel multiple products share a formula, and formula is unreasonable
2. There is no distinction between monarch and minister medicines, the dosage of monarch medicine is small, and the bactericidal effect is poor

Method used

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  • Anti oral Helicobacter pylori traditional Chinese medicine toothpaste
  • Anti oral Helicobacter pylori traditional Chinese medicine toothpaste

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Take 1.0 kg of forsythiaside, 0.1 kg of total alkaloids of matrine, 0.1 kg of buckwheat glycosides, 0.5 kg of glycyrrhetinic acid, 0.5 kg of tea polyphenols, 5 kg of lactoferrin, 0.01 kg of lanthanum bismuth phytate, and 0.01 kg of enzyme preparation , 8 kg of glycerin, 3 kg of sodium lauryl sulfate, 2 kg of hydroxymethyl cellulose, 5 kg of sorbitol, 3 kg of silicon dioxide, deionized water to 100 kg, fully stirred, and a homogenizer for two After sub-homogenization, evacuated, filled, and made into oral Helicobacter pylori Chinese medicine toothpaste. In 860 cases of continuous use for three months, oral HP turned negative to more than 90%, without cariogenic bacteria.

Embodiment 2

[0033] Take 1.5 kg of forsythiaside, 0.1 kg of total alkaloids of matrine, 0.2 kg of buckwheat glycosides, 0.2 kg of glycyrrhetinic acid, 0.4 kg of tea polyphenols, 3 kg of lactoferrin, 0.01 kg of lanthanum bismuth phytate, and 0.01 kg of enzyme preparation , 6 kg of glycerin, 1 kg of sodium lauryl sulfate, 1 kg of hydroxymethyl cellulose, 5 kg of sorbitol, 3 kg of silicon dioxide, and 100 kg of deionized water. The above-mentioned raw materials are fully stirred, homogenized for the second time with a homogenizer, vacuumed, filled, and made into oral Helicobacter pylori Chinese medicine toothpaste. In 1,000 cases of continuous use for three months, oral HP turned negative to more than 90%, without cariogenic bacteria.

Embodiment 3

[0035] Take the toothpaste prepared in Example 1 and apply it to the oral ulcers of patients with oral ulcers, three times a day for seven consecutive days, and it is completely cured.

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Abstract

The invention relates to traditional Chinese medicine toothpaste and particularly relates to anti-oral helicobacter pylori traditional Chinese medicine toothpaste. According to existing sterilizing toothpaste, antibiotics are added to damage the micro-ecological environment of the oral cavity, so that the resistance to drugs of bacteria is increased. The toothpaste provided by the invention is prepared from the following raw materials in parts by weight: 0.5-2 parts of forsythiaside, 0.1-0.3 part of wild buckwheat glycoside, 0.05-1 part of tea polyphenol, 0.1-0.5 part of glycyrrhetinic acid, 1-5 parts of lactoferrin, 0.005-0.01 part of bismuth lanthanum phytate, 0.001-0.05 part of enzymic preparation, 1-8 parts of glycerinum, 0-3 parts of lauryl sodium sulfate, 0.5-2 parts of hydroxymethyl cellulose, 0.1-10 parts of sorbitol, 1-3 parts of carbon dioxide and the balance of deionized water, totally 100 parts. The toothpaste provided by the invention has the advantages that the monarch drug forsythiaside is matched with the ministerial drug, the adjuvant drug and the conductant drug, so that the toothpaste has a quick killing effect to HP bacterium; the toothpaste can effectively inhibit and eliminate dental plaque and effectively kill cariogenic bacteria to prevent decayed teeth; the toothpaste is convenient to use.

Description

Technical field [0001] The invention relates to a Chinese medicine toothpaste, in particular to a Chinese medicine toothpaste against oral Helicobacter pylori. Background technique [0002] Helicobacter pylori is a gram-negative, microaerobic bacteria that lives in various areas of the mouth, stomach, and duodenum. Helicobacter pylori can cause gastric cancer, peptic ulcer, and gastritis in children and adults. It is also closely related to recurrent oral ulcers, periodontitis, iron deficiency anemia, idiopathic thrombocytopenic purpura, growth retardation and so on. The infection rate of the Chinese population is 59%; and it is increasing at an average annual rate of 0.5-1%. The World Health Organization declared Helicobacter pylori in the stomach as a microbial carcinogen, and was the first prokaryotic organism to be confirmed to be carcinogenic to humans. As the entrance to the digestive tract, the presence of Helicobacter pylori in the oral cavity affects the efficacy of He...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/97A61K8/49A61K8/60A61K8/63A61K8/64A61K38/43A61Q11/00A61P31/02A61P1/02A61P35/00A61P1/04A61P37/08
Inventor 卞雪莲郁世芳徐春芬刘娟叶佩华张静盛铀任一斌
Owner SHANGHAI LIKANG DISINFECTION HIGH TECH
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