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Traditional Chinese medicine composition for treating diarrhea as well as preparation and application thereof

A kind of composition and technology of traditional Chinese medicine, applied in the preparation and application of traditional Chinese medicine composition, the field of traditional Chinese medicine composition for treating diarrhea in children and treating diarrhea

Inactive Publication Date: 2014-06-25
南京海思创新生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] At present, there are relatively few alternative Chinese medicines for treating infantile diarrhea in the pediatric market, and most of them are oral preparations, which bring inconvenience to parents and children. poor sex

Method used

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  • Traditional Chinese medicine composition for treating diarrhea as well as preparation and application thereof
  • Traditional Chinese medicine composition for treating diarrhea as well as preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0085] Example 1, the traditional Chinese medicine composition for treating diarrhea, the weight ratio composition of each component is: 1 g of cinnamon, 1 g of dried ginger, 1 g of Artemisia argyi, 1 g of fennel, and 1 g of Evodia rutaecarpa. The above medicinal materials are pulverized into fine powder, sieved and mixed evenly to obtain a powder. When used, fix it with an applicator such as gauze, tape or rubber plaster, and apply it on the navel.

Embodiment 2

[0086] Example 2, the traditional Chinese medicine composition for treating diarrhea, the weight ratio composition of each component is: cassia cinnamon 10g, dried ginger 10g, mugwort leaves 9g, cumin 10g, and Evodia rutaecarpa 8g. Use steam distillation to extract the volatile oils from cinnamon, dried ginger, mugwort leaves, cumin, and Evodia rutaecarpa, and filter to obtain the filtrate and medicinal residues; the volatile oils are clathrated with β-cyclodextrin; the obtained medicinal residues are extracted with ethanol, filtered, and concentrated. Obtain ethanol extract; add volatile oil components, add auxiliary materials such as matrix, humectant, preservative, transdermal accelerator, etc. to make ointment. When in use, cover it with gauze, fix it with adhesive tape or rubber plaster, etc., and apply it on the navel.

Embodiment 3

[0087] Example 3, the traditional Chinese medicine composition for treating diarrhea, the weight ratio of each component is: 10g of cinnamon, 1g of dried ginger, 9g of Artemisia argyi, 1g of cumin, and 8g of Evodia rutaecarpa. Use supercritical carbon dioxide to extract the volatile oils from cinnamon, dried ginger, mugwort leaves, cumin, and Evodia rutaecarpa, and filter to obtain the filtrate and medicinal residues; the volatile oils are clathrated with β-cyclodextrin; the obtained medicinal residues are extracted with ethanol, filtered, and concentrated , to obtain ethanol extract; add volatile oil components, add commonly used moisturizers, preservatives, antioxidants, transdermal accelerators, etc., then add calamine powder, and matrix (fully infiltrated by carbomer and HPMC, add water, glycerin composition ) and mix well to obtain the gel. When in use, cover it with gauze, fix it with adhesive tape or rubber plaster, etc., and apply it on the navel.

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Abstract

The invention provides a traditional Chinese medicine composition for treating diarrhea as well as a preparation and application thereof. The traditional Chinese medicine composition comprises the following medicinal raw materials: 1-10 parts of cinnamon, 1-10 parts of dried ginger, 1-9 parts of folium artemisiae argyi, 1-10 parts of fennel and 1-8 parts of evodia rutaecarpa. According to the optimization scheme, one of or a mixture of several of 2-7 parts of amomum tsao-ko, 1-5 parts of piperis longi, 2-9 parts of pomegranate peel, 0.1-2 parts of borneol, 0.5-4 parts of asarum, 2-6 parts of gallnut, 2-10 parts of myristica fragrans and 2-10 parts of dried orange peel is added. The traditional Chinese medicine composition can be used for preparing a pharmaceutically acceptable external preparation dosage form according to a conventional process. The traditional Chinese medicine composition quickly taking an effect for treatment of diarrhea with small side effects and the external preparation thereof are prepared specific to current conditions that most of medicines for treating diarrhea, which are clinically applied at present, are preparations for oral administration, are inconvenient to carry and take for parents and children and have poor compliance, and the traditional Chinese medicine composition and the preparation thereof have the effects of warming channels, expelling cold and stopping diarrhea by invigorating the spleen. The invention also provides an application of the medicine in preparation of externally applied medicines for treating diarrhea.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating diarrhea. The present invention also relates to the preparation and application of the traditional Chinese medicine composition for treating diarrhea, which is especially suitable for treating diarrhea in children. Background technique [0002] Diarrheal disease is a group of diseases caused by multiple etiologies and factors, mainly caused by diarrhea. It is one of the important diseases that seriously endanger human health. It affects about 4 billion people worldwide every year and causes 3 to 4 million deaths. Diarrheal disease is also a common and frequently-occurring disease in pediatrics, and is one of the diseases with the highest incidence rate in childhood. The annual incidence of diarrheal diseases in children under 5 years old in my country is 201%, with an average of 3.5 cases per child-year. Diarrh...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/12A61K31/045A61K35/64
Inventor 储益平管伦兴朱华荣
Owner 南京海思创新生物科技有限公司
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