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A traditional Chinese medicine compound with intestinal mucosal protection after chemotherapy and its application

A technology of intestinal mucosa and traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve the problems of congestion and edema of gastrointestinal mucosa epithelial cells, damage to the normal response of the body, intestinal barrier dysfunction, etc. , The effect of protecting the intestinal mucosa

Active Publication Date: 2016-12-07
XINJIANG UYGUR AUTONOMOUS REGION CHINESE MEDICINE HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at the same time as radiotherapy and chemotherapy, it can damage the normal response of the body, destroy the balance of the body's internal environment, and worsen the imbalance of the body. Clinical symptoms of gastrointestinal dysfunction such as vomiting, diarrhea, and constipation

Method used

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  • A traditional Chinese medicine compound with intestinal mucosal protection after chemotherapy and its application
  • A traditional Chinese medicine compound with intestinal mucosal protection after chemotherapy and its application
  • A traditional Chinese medicine compound with intestinal mucosal protection after chemotherapy and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0021] Example: Preparation of Compound Alcoholic Extract and Verification of Intestinal Mucosa Protection

[0022] 1. Preparation of alcoholic extract of traditional Chinese medicine Fusheng Fang

[0023] The preparation of traditional Chinese medicine compound (Yiqi Fusheng Fang) is in proportion (18-22 parts of Dangshen, 28-32 parts of Astragalus, 18-22 parts of Poria cocos, 13-17 parts of fried Atractylodes macrocephala, 13-17 parts of nutmeg, 13- 17 parts, 13-17 parts of seabuckthorn, 8-12 parts of bitter bean, 4-8 parts of yew) Weigh a certain amount of decoction pieces, add 8 times the volume of 75% ethanol, reflux extraction and decoction twice, 1 hour each time , combine the decoctions, centrifuge, concentrate, and dry to dryness to obtain the ethanol extract of Fusheng Fang, a traditional Chinese medicine. The yield of the alcohol extract of the traditional Chinese medicine Fusheng Fang is 1g crude drug / 0.214g alcohol extract. Before the experiment, an appropriate ...

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Abstract

The invention discloses a traditional Chinese medicine compound capable of protecting intestinal mucosae after chemotherapy and application thereof. The traditional Chinese medicine compound is prepared from the following bulk drugs by weight: 18 to 22 parts of Dangshen, 28 to 32 parts of milkvetch root, 18 to 22 parts of Poria cocos, 13 to 17 parts of fried atractylodes, 13 to 17 parts of mutmeg, 13 to 17 parts of fiveleaf akebia fruit, 13 to 17 parts of sea-buckthorn, 8 to 12 parts of Sophora alopecuroide and 4 to 8 parts of Chinese yew. According to the traditional Chinese medicine compound provided by the invention, a scientific ratio of the bulk drugs is employed, and the bulk drugs are coordinated with each other, mutually promote and exert a synergistic interaction effect; the compound can strengthen healthy qi, tonify blood, benefit yin, protect intestinal mucosae and substantially mitigates gastrointestinal reaction caused by chemotherapy.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine compound capable of protecting intestinal mucosa after chemotherapy and its application. Background technique [0002] Adjuvant radiotherapy and chemotherapy after surgery is a common method of cancer treatment today. However, at the same time, radiotherapy and chemotherapy can damage the normal reaction of the body, destroy the balance of the body's internal environment, and worsen the imbalance of the body, and easily cause congestion and edema of the gastrointestinal mucosal epithelial cells, leading to intestinal barrier dysfunction, nausea, Clinical symptoms of gastrointestinal dysfunction such as vomiting, diarrhea, and constipation. Intestinal barrier function refers to the function of the intestinal epithelium to separate the substances in the intestinal lumen and prevent the invasion of pathogenic antigens, including mechanical ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/489A61P1/04
Inventor 邓皖利陆明吕书勤王昕宇段春燕王巧琳何娜娜李向黎任小娟林燕马金丽吴涛肖亮亮
Owner XINJIANG UYGUR AUTONOMOUS REGION CHINESE MEDICINE HOSPITAL
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