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Disinfectant composition and application thereof

A composition and disinfectant technology, applied in the direction of drug combination, active ingredients of alkali/alkaline earth metal chlorides, active ingredients of aluminum/calcium/magnesium, etc., can solve problems such as electrolyte loss, shock, and cell dehydration

Inactive Publication Date: 2014-06-04
WUHAN YAOGU BIOLOGICAL ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

On the other hand, because the electrolyte balance is damaged, it is easy to cause electrolyte loss and cell dehydration, which can cause shock in severe cases, so it is necessary to supplement electrolyte balance salt in an emergency

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Example 1 Preparation of Disinfectants Containing Electrolyte Balanced Salts and Chlorhexidine

[0014] Take 1000ml of purified water, add 0.1g of chlorhexidine acetate, stir well to dissolve, then add 5.26g of sodium chloride, 3.68g of sodium acetate, 5.02g of sodium gluconate, 0.37g of potassium chloride and 0.30g of magnesium chloride, and stir well to make dissolve.

Embodiment 2

[0015] Example 2 Preparation of Disinfectants Containing Electrolyte Balanced Salts and Chlorhexidine

[0016] Take 1000ml of purified water, add 0.1g of chlorhexidine gluconate, stir well to dissolve, then add 5.26g of sodium chloride, 3.68g of sodium acetate, 5.02g of sodium gluconate, 0.37g of potassium chloride and 0.30g of magnesium chloride, and stir well to dissolve.

Embodiment 3

[0017] Example 3 Preparation of Disinfectants Containing Electrolyte Balanced Salts and Chlorhexidine

[0018] Take 1000ml of purified water, add 0.1g of chlorhexidine acetate, stir well to dissolve, then add 6.40g of sodium chloride, 3.90g of sodium acetate, 1.70g of sodium citrate, 0.75g of potassium chloride, 0.48g of calcium chloride and magnesium chloride 0.30g, stir well to dissolve.

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PUM

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Abstract

The invention relates to a disinfectant composition with electrolyte balance salts and chlorhexidine, and an application of the disinfectant composition to treatment of partial bacterial infection.

Description

technical field [0001] The invention relates to a disinfectant composition containing balanced salt of electrolyte and chlorhexidine. Background technique [0002] Chlorhexidine, also known as chlorhexidine or chlorhexidine, is a colorless or white powder, odorless, non-hygroscopic, and is a biguanide disinfectant. It is a safe disinfectant with low toxicity, corrosion and irritation. There are chlorhexidine acetate, chlorhexidine hydrochloride and chlorhexidine gluconate. Chlorhexidine has good disinfection effect, low cost and stable property. [0003] Chlorhexidine solution is a colorless clear liquid with a slightly bitter taste. The antibacterial effect on Gram-positive and negative bacteria is stronger than that of benzalkonium bromide and other disinfectants. Still effective in the presence of serum, blood, etc. The mechanism of action is that it is adsorbed on the permeability barrier of the bacterial cytoplasmic membrane, allowing the cell contents to leak out ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/14A61K33/06A61P31/04A61P31/02A61P3/12A61K31/155
Inventor 周利娟颜锵
Owner WUHAN YAOGU BIOLOGICAL ENG
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