Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of pharmaceutical composition of balanced salt flushing liquid

A technology of flushing liquid and balanced salt, applied in the field of medicine, can solve problems such as antibacterial and poor wound pollution prevention, and achieve the effects of facilitating mucosal repair, reducing pain, and accelerating speed and quality.

Active Publication Date: 2019-04-02
YANGTZE RIVER PHARM GRP GUANGZHOU HAIRUI PHARM CO LTD +1
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, the current surgical irrigation solution can not prevent postoperative tissue adhesion and promote wound healing, and the effect of antibacterial and wound pollution prevention is poor, which cannot meet the requirements of modern clinical practice

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of pharmaceutical composition of balanced salt flushing liquid
  • A kind of pharmaceutical composition of balanced salt flushing liquid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1, the preparation of high straight chain cross-linked starch

[0034] Dissolve amylose in water, the solid-to-liquid ratio of the amylose to water is 1g:5ml, stir it evenly to form an emulsion, add a compound cross-linked mixture consisting of sodium tripolyphosphate and calcium chloride in a weight ratio of 5:2 Linking agent, the addition of the composite crosslinking agent is 0.4% of the total weight of amylose, adjust the pH to 10 with NaOH with a mass concentration of 10%, heat to 65°C, stir for 2h, cool, filter, wash with water , dried, crushed, that is.

Embodiment 2

[0035] Embodiment 2, the preparation of bletilla striata polysaccharide zinc

[0036] Take Bletilla striata polysaccharide and zinc acetate and mix evenly. The weight ratio of Bletilla striata polysaccharide to zinc acetate is 1:5, then add water for injection and heat to 50°C, and use citric acid-sodium citrate buffer to adjust the pH value to 8.2. Stir the reaction for 2 hours, dialyze the reaction liquid under running water for 24 hours, and then dialyze it with purified water for 24 hours, collect the dialyzed solution, dry under reduced pressure, and obtain Bletilla striata polysaccharide zinc.

Embodiment 3

[0037] Embodiment 3, a kind of pharmaceutical composition of balanced salt flushing solution

[0038] The pharmaceutical composition of the balanced salt flushing solution consists of the following components and their concentrations:

[0039] Magnesium vitamin C phosphate 6g / L, high linear cross-linked starch 4g / L, Bletilla striata polysaccharide zinc 1g / L, sodium chloride 2g / L, sodium acetate 3g / L and potassium chloride 0.2g / L, the balance is water for injection The high linear cross-linked starch is the high linear cross-linked starch obtained in Example 1, and the Bletilla striata polysaccharide zinc is the Bletilla striata polysaccharide zinc obtained in Example 2.

[0040] Preparation:

[0041] S1 Take half of the water for injection and heat it to 45°C, add high linear cross-linked starch and Bletilla striata polysaccharide zinc, and stir at constant temperature for 10 minutes to obtain the mixed solution I;

[0042] S2 Add vitamin C magnesium phosphate and sodium ace...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle sizeaaaaaaaaaa
Login to View More

Abstract

The invention belongs to the technical field of medicines, and particularly relates to a pharmaceutical composition for balancing salt flushing fluid. The pharmaceutical composition is composed of vitamin C phosphate magnesium, high linear crosslinked starch, white peony polysaccharide zinc, sodium chloride, sodium acetate, potassium chloride and water for injection. The pharmaceutical compositionprepared can prevent tissue adhesion during an operation or post-operation, can obtain clearer vision during the operation, be beneficial for the smooth operation of the surgery, prevent adhesion ofpostoperative tissues, and can effectively reduce the incidence of postoperative complications; the pharmaceutical composition also has the functions of sterilizing, scavenging free radicals, preventing wound contamination, effectively promoting wound healing, and reducing patient suffering, and is a high-safety and low-irritating pharmaceutical composition for the balancing salt flushing fluid.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition of a balanced salt flushing solution. Background technique [0002] Tissue adhesion is a common pathological reaction, which is an abnormal structure formed by the combination of connective tissue fibers and adjacent tissues or organs due to tissue trauma during surgery. Tissue adhesions will occur during or after abdominal and pelvic surgery, orthopedic surgery, urological surgery, gynecological surgery, etc., which will seriously affect the operation process and easily cause serious postoperative complications, such as abdominal and pelvic pain, intestinal obstruction, Infertility, etc., severe adhesions often cause difficulties for reoperation. Therefore, the problem of surgical adhesion has always been a common thorny problem in surgical operations. [0003] During surgery, in order to obtain a clearer view, various methods and meas...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/30A61K31/718A61K33/06A61K31/715A61K31/665A61K33/14A61K31/19A61P41/00A61P17/02A61P31/02A61P39/06
CPCA61K31/19A61K31/665A61K31/715A61K31/718A61K33/06A61K33/14A61K33/30A61P17/02A61P31/02A61P39/06A61P41/00A61K2300/00
Inventor 钟艳红施猛夏春森任亚东刘志强王学文袁海成
Owner YANGTZE RIVER PHARM GRP GUANGZHOU HAIRUI PHARM CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com