Antrodia cinnamomea effervescent tablet and preparation method thereof
A technology of effervescent tablets and Antrodia cintrodia, which is applied in medical formulas, medical preparations of non-active ingredients, drug delivery, etc., can solve problems such as restrictions on the utilization of Antrodia cinnamomea, low utilization rate of active ingredients in Antrodia cintrodia, inconvenient taking and carrying, etc., to achieve Increase solubility, safe and convenient food, and enhance stability
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[0016] The embodiment of the present invention also provides a kind of preparation method of Antrodia camphorata effervescent tablet, comprises the following steps:
[0017] Mix the Antrodia camphorata extract, filler and sweetener evenly to make a mixture;
[0018] Mixing the mixture with an alkali source and a lubricant to make alkaline granules;
[0019] Mixing the mixture with an acid source and a lubricant to make acidic granules;
[0020] The acidic granules and basic granules are compressed into tablets to obtain the effervescent tablets of Antrodia camphorata.
[0021] Specifically, the Antrodia camphorata extract includes the water extract of Antrodia camphorata and / or the alcohol extract of Antrodia camphorata coated with cyclodextrin. Among them, the preparation method of the water extract of Antrodia Cinnamomea is as follows: take the Antrodia Cinnamomea raw material and water in a weight ratio of 1: (5-15), extract at 80-95°C for 30-60 minutes, filter, and take ...
Embodiment 1
[0028] Take the fruiting body of Antrodia camphorata obtained by the basswood cultivation method, wash and chop. Add the Antrodia camphorata raw material and water at a volume ratio of 1:10, extract at 80°C for 60 minutes, filter, and take the filtrate; repeat twice; combine the filtrates obtained three times to obtain the water extract of Antrodia camphorata. Vacuum-concentrate at 80°C to form a paste, then vacuum-dry with microwaves, pulverize, and pass through an 80-mesh sieve to obtain powdery water extract of Antrodia camphorata.
[0029] Add anhydrous ethanol 8 times the weight of the Antrodia camphorata raw material to the above water-extracted Antrodia camphorata raw material, reflux at 90°C for 1 hour, filter, and take the filtrate; repeat three times, and combine the obtained filtrates three times to obtain the Antrodia camphorata ethanol extract. According to the volume ratio of β-cyclodextrin: pure water = 1:20, add β-cyclodextrin and purified water and mix, wherei...
Embodiment 2
[0033] The mycelium of Antrodia camphorata obtained by submerged liquid fermentation is taken, washed and pulverized. Add the Antrodia camphorata raw material and water at a volume ratio of 1:10, extract at 80°C for 60 minutes, filter, and take the filtrate; repeat twice; combine the filtrates obtained three times to obtain the water extract of Antrodia camphorata. Vacuum-concentrate at 80°C to form a paste, then vacuum-dry with microwaves, pulverize, and pass through an 80-mesh sieve to obtain powdery water extract of Antrodia camphorata.
[0034]Add anhydrous ethanol 8 times the weight of the Antrodia camphorata raw material to the above water-extracted Antrodia camphorata raw material, reflux at 90°C for 1 hour, filter, and take the filtrate; repeat three times, and combine the obtained filtrates three times to obtain the Antrodia camphorata ethanol extract. According to the volume ratio of β-cyclodextrin: pure water = 1:20, add β-cyclodextrin and purified water and mix, wh...
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