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Compound lipid-decreasing soft capsule and preparation method thereof

A compound lipid-lowering and soft capsule technology, which is applied in capsule delivery, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve problems such as poor taste, decoction, inconvenient carrying and taking, and incomplete decoction of ingredients The effect of inhibiting the formation of atherosclerotic plaque

Active Publication Date: 2014-04-23
武汉市元大生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is that, in view of the disadvantages of decoction, carrying, and inconvenient consumption in traditional Chinese medicine decoctions, incomplete decoction of ingredients, and poor taste, the present invention mainly utilizes the compatibility relationship between Chinese medicine and raw materials , develop traditional Chinese medicine prescriptions that can effectively lower blood lipids, and make them into modern soft capsule dosage forms that can be accurately quantified by modern pharmaceutical means, improve bioavailability, make the drug effect of the preparation of the present invention more significant, take more convenient, and cover up the traditional Chinese medicine. Bad smell and bitter taste, easy to accept, better to achieve lipid-lowering effect

Method used

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  • Compound lipid-decreasing soft capsule and preparation method thereof
  • Compound lipid-decreasing soft capsule and preparation method thereof
  • Compound lipid-decreasing soft capsule and preparation method thereof

Examples

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Embodiment 1

[0032] 1. Preparation: Wash and dry Ginkgo biloba leaves, crush them through a 80-mesh sieve with a pulverizer, and store the powder in a brown jar; grind Panax notoginseng through an 80-mesh sieve to obtain Sanqi fine powder; pass red yeast rice through an 80-mesh sieve , to get fine powder of red yeast rice;

[0033] 2. Extraction and concentration: 1) Weigh 500g of ginkgo leaf fine powder and 200g of notoginseng fine powder, add them to 70% ethanol at a concentration of 10 times, heat to 65°C in a water bath, and extract for 1.5h. Stir once every 10 minutes, and filter with gauze to obtain the first extract; add the remaining residue to 70% ethanol at 8 times the concentration, and continue to extract in a 65°C water bath for 1.5 hours, and stir once every 10 minutes. Filter through gauze, discard the medicinal residues, obtain the second extract, combine the two extracts, and set aside;

[0034] 2) Take the above-mentioned filtrate, put it in a vacuum decompression concen...

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Abstract

The invention provides a compound lipid-decreasing soft capsule and a preparation method thereof. The compound lipid-decreasing soft capsule is characterized by mainly comprising the following main parts: folium ginkgo, pseudo-ginseng, gynostemma pentaphylla, red yeast rice and seabuckthorn seed oil. According to the invention, the compatibility between traditional Chinese medicines and raw materials is mainly used, so as to develop a Chinese medicinal formulae for effectively preventing and decreasing lipid, meanwhile, for overcoming defects of inconvenience in decoction, carrying and taking, incomplete decocted components, bad mouthfeel and the like in the conventional dosage form decoction at present, the decoction is prepared into modern soft capsule form achieving accurate quantification through a modern drug mean, the bioavailability is improved, the compound lipid-decreasing soft capsule is enabled to be more remarkable in effect and convenient to take, objectionable odors and bitter taste in the traditional Chinese medicines can be covered up, so as to be accepted by people easily, and the lipid-decreasing effect can be better achieved.

Description

technical field [0001] The invention relates to the technical field of medicine and health care, in particular to a compound Jiangzhi soft capsule and a preparation method thereof. Background technique [0002] Hyperlipidemia belongs to the category of "phlegm turbidity" and "blood stasis" in traditional Chinese medicine. Traditional Chinese medicine believes that phlegm retention is due to dysfunction of the lungs, spleen, kidneys and other viscera, which hinders the transportation, distribution, and excretion of body fluid, resulting in stasis in the body, combined with cold and heat. Therefore, the pathological changes of hyperlipidemia are mainly closely related to the dysfunction of the liver, spleen, and kidney, and clinical treatment is mostly based on syndrome differentiation of qi, blood, phlegm, and stasis. [0003] With the improvement of people's living standards in our country, the dietary structure has undergone significant changes. The intake of saturated fat...

Claims

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Application Information

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IPC IPC(8): A61K36/424A61K9/48A61P3/06
Inventor 朱玲刘敏
Owner 武汉市元大生物科技有限公司
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