Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Capsule for clearing away turbid and tonifying kidneys

A technology of clearing turbidity and nourishing the kidney and capsules, which is applied in capsule delivery, plant raw materials, urinary system diseases, etc. It can solve problems such as cataracts, femoral head necrosis, adrenal insufficiency, water and sodium retention hypertension, etc., to delay renal failure. Damage, improved blood flow, low recurrence rate

Active Publication Date: 2014-03-19
XIANGYU PHARMA
View PDF3 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If you take adrenal corticosteroids for a long time, it has been proven that there will be a lot of adverse reactions: fat metabolism disorder, edema, abnormal body fat distribution, etc.; protein decomposition, increased metabolism, negative balance of nitrogen, and muscle atrophy , muscle weakness, difficult wound healing, etc.; the disorder of sugar metabolism leads to hyperglycemia and diabetes; Those who are prone to peptic ulcer and severe gastric perforation can lead to gastric perforation; pleasure and excitement in the nervous system can lead to insomnia, and severe psychotic seizures can occur; due to the formation of inhibitory antibodies, infection and tuberculosis are more likely to occur and spread; a large number, Long-term medication can also cause cataract and aseptic necrosis of the femoral head; such as sudden drug withdrawal or surgical infection, it can cause adrenal insufficiency, leading to nausea, vomiting, abdominal pain, shock, etc.
Therefore, the use of standardized hormone therapy in Western medicine has poor effects, many side effects, and a high recurrence rate.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A Qingzhuo Yishen capsule for the treatment of nephrotic syndrome is prepared from the following raw materials: 100g of Cordyceps sinensis, 1400g of Astragalus, 280g of Salvia miltiorrhiza, 280g of safflower, 280g of Suanzaoren, 500g of Dodder, and 100g of Rhubarb.

[0036] The preparation method of the Qingzhuo Yishen Capsules is as follows: Weigh the raw materials by weight for subsequent use

[0037] (1) Take Cordyceps sinensis and pulverize it into fine powder;

[0038] (2) Take Astragalus, Salvia miltiorrhiza, safflower, Suanzaoren and decoct twice with water, add 10 times the amount of water for the first time, decoct for 1.5 hours, and filter to obtain filtrate and medicinal residues;

[0039] (3) Add rhubarb to the medicinal residues obtained in step (2) and add 8 times of water, decoct for 1 hour, and filter to obtain a filtrate

[0040] (4) Combine the filtrates of step (2) and step (3), concentrate into a clear paste with a relative density of 1.14-1.16 (80-...

Embodiment 2

[0046] A kind of Qingzhuo Yishen capsule, it is prepared from the raw material of following weight:

[0047] Astragalus 1400g, Salvia 280g, Safflower 280g, Suanzaoren 280g, Dodder Seed 500g,

[0048] Rhubarb 100g, Seaweed 100g, Epimedium 80g, Curcuma 80g, Aconite 70g,

[0049] Gorgon 70g, Poria 70g, Atractylodes 60g, Melon Seed 60g, Pueraria Root 60g,

[0050] 50g white lentils, 50g purslane, 50g orange shell, 40g mulberry, 40g Ling Xiaohua,

[0051] Bai Bu 30g, Pinellia 30g, Goji berry 30g.

[0052] The preparation method of the Qingzhuo Yishen Capsule is as follows: take the raw material by weight for subsequent use

[0053] (1) Take aconite, Gorgon, Poria, Atractylodes, Citrus, mulberry, Ling Xiaohua, Baibu, Pinellia and crush into fine powder;

[0054] (2) Take Astragalus, Salvia miltiorrhiza, safflower, Suanzaoren and decoct in water, add 10 times the amount of water, decoct for 1.5 hours, and filter to obtain filtrate and medicinal residues;

[0055] (3) adding rhub...

Embodiment 3

[0061] clinical information

[0062] Observation cases were patients with admission treatment, with a total of 136 patients, of which 70 men, 66 women, aged 21-70, an average age of 32.7 years. There were 46 people in the control group, 45 people in the Example 1 group, and 45 people in the Example 2 group.

[0063] Inclusion criteria:

[0064] (1) massive proteinuria, quantitative urine protein ≥ 3.5g / d; (2) hypoalbuminemia, plasma albumin ≤ 30g / L; (3) edema; (4) hyperlipidemia. Two of (1) and (2) are prerequisites for diagnosis. Excluding nephrotic syndrome caused by systemic systems and congenital genetic diseases, those who have increased blood urea nitrogen (BUN), creatinine (SCR) or endogenous creatinine clearance (CCR) before treatment.

[0065] treatment method:

[0066] Control group: Oral prednisone at a dose of 1 mg / (kg·d), taken in the morning, with a maximum daily dose not exceeding 60 mg. When the patient's liver function declines, the same dose of prednis...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a capsule for clearing away turbid and tonifying kidneys. The capsule is prepared from the following raw materials by weight: 100g of cordyceps sinensis, 1400g of astragalus membranaceus, 280g of root of red-rooted salvia, 280g of flowers carthami, 280g of spina date seeds, 500g of semen cuscutae and 100g of rheum officinale. The applied capsule for clearing away turbid and tonifying the kidneys is used for treating both deficiency and excess and treating both symptoms and root causes, is accurate in curative effect, rigorous in formula, and simple and convenient to prepare, and has a broad application prospect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a Qingzhuo Yishen Capsule used for treating nephrotic syndrome by using Chinese herbal medicines as raw materials. Background technique [0002] Kidney disease has now become one of the major diseases endangering public health. And due to irregular treatment, drug abuse and unhealthy lifestyle, the incidence of kidney disease in my country has also increased year by year. Nephrotic syndrome (NS) refers to a group of glomerular lesions caused by a variety of etiologies, mainly including increased glomerular basement membrane permeability and decreased glomerular filtration rate. syndrome. Nephrotic syndrome is not an independent disease, but a group of syndromes in glomerular diseases. Its typical symptoms are massive proteinuria, hypoalbuminemia, high edema, and hyperlipidemia. It can be caused by many kinds of kidney diseases, and it is now ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/725A61K36/9066A61K9/48A61P13/12
Inventor 林凡友
Owner XIANGYU PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products