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Chinese medicinal preparation for treating recurrent oral ulceration

A traditional Chinese medicine preparation and oral ulcer technology, applied in the field of traditional Chinese medicine, can solve the problems of patients with heavy economic and mental burden, interference with diet and work and rest, and no specific treatment, etc., and achieve the effect of no toxic and side effects, not easy to relapse, and remarkable and reliable curative effect

Active Publication Date: 2014-02-19
辽宁省欣时代生物医药产业技术研究有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although oral ulcer is a "minor problem", it brings great pain and troubles to the patient and his family. After suffering from oral ulcer, the patient's normal diet and work and rest are disturbed, and the pain causes insomnia, irritability and tension. , depression, loss of interest in work and life, etc., especially recurrent oral ulcers, the financial and mental burden on patients is even heavier
[0003] In terms of western medicine, there is no effective therapy for recurrent oral ulcers. At present, eliminating the pathogenic factors, reducing symptoms, promoting healing, and reducing recurrence are the principles for the treatment of recurrent oral ulcers.

Method used

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  • Chinese medicinal preparation for treating recurrent oral ulceration

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A traditional Chinese medicine preparation for recurrent oral ulcer, which is prepared from the following raw materials in parts by weight,

[0028] 20 parts of Qingdai, 18 parts of Baibu, 15 parts of Dijincao, 15 parts of Curcuma, 12 parts of Gualou,

[0029] Banzhilian 12 parts, Phellodendron 12 parts, Bellflower 10 parts, Gardenia 10 parts, Licorice 10 parts,

[0030] 10 parts of Astragalus, 10 parts of Ophiopogon japonicus, 7 parts of dark plum, 7 parts of Prunella vulgaris, 5 parts of Albizia juniper,

[0031] 5 parts of melon seeds, 5 parts of Uncaria, 3 parts of mulberry leaves,

[0032] Above-mentioned Chinese medicine preparation preparation method is:

[0033] (1) Take the bulk drug (proportioning unit: gram) of the above-mentioned parts by weight, and set aside;

[0034] (2) Take Baibu, Dijincao, Curcuma, Scutellaria barbata, Licorice, Prunella vulgaris, Albizia Albizia, and Uncaria, mix evenly, add 5 times the weight of water, soak for 30 minutes, boil wi...

Embodiment 2

[0038] zoology experiment

[0039] The acute toxicity test using mice showed that compared with the control group, there was no significant difference in the mice after administration. The experiment was observed for two consecutive weeks, and the general condition, food intake, drinking water, and weight gain of the mice were all normal. On the day of administration and within two weeks after administration, no animal died, suggesting that the drug has low acute toxicity and is safe for clinical use.

[0040] long-term toxicity test

[0041] Select 40 SD rats, half male and half male. Divide into 2 groups at random according to body weight, i.e. control group (equal dose of distilled water), Chinese medicine group of the present invention. 20 in each group, half male and half male. Each group of animals is administered intragastrically once a day, and after continuous administration for 1 month, each 10 of the matched group and the Chinese medicine group of the present inv...

Embodiment 3

[0043] clinical information:

[0044]Materials and methods: In order to further investigate the clinical curative effect and safety of the traditional Chinese medicine preparation of the present invention, we selected 70 cases of recurrent oral ulcer patients to conduct clinical observation on the curative effect of the medicine of the present invention. Randomly divided into a treatment group of 35 cases and a control group of 35 cases; aged 21-55 years, with an average age of 32 years, 33 cases of male patients and 37 cases of female patients, there were no significant differences in gender, age, course of disease, etc. between the two groups. Sexual differences are comparable.

[0045] standard constrain

[0046] (1) Repeated attacks of oral mucosal ulcers (more than 10 attacks per year), continuous attacks for more than 1 year -5 cases, exudation, hyperemia, edema and other manifestations were mainly seen.

[0047] treatment method

[0048] The treatment group was give...

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Abstract

The invention belongs to the technical field of medicine and discloses a Chinese medicinal preparation for treating recurrent oral ulceration. The Chinese medicinal preparation for treating recurrent oral ulceration is prepared from the following raw materials: 20 parts of natural indigo, 18 parts of sessile stemona root, 15 parts of humifuse euphorbia herb, 15 parts of curcuma zedoaria, 12 parts of snake gourd fruit, 12 parts of barbed skullcap herb, 12 parts of amur cork tree bark, 10 parts of platycodon grandiflorus, 10 parts of gardenia, 10 parts of liquorice, 10 parts of astragalus, 10 parts of ophiopogon japonicus, 7 parts of dark plum fruit, 7 parts of prunella vulgaris, 5 parts of cortex albiziae, 5 parts of muskmelon seed, 5 parts of uncaria tomentosa and 3 parts of mulberry leaf. The Chinese medicinal preparation disclosed by the invention has a short treatment course for treating recurrent oral ulceration and has a high total effective rate; after the Chinese medicinal preparation is applied and recurrent oral ulceration is healed, recurrent oral ulceration is difficult to recur moreover, the process is simple, the production cost is reduced and the economical burden of a patient is reduced.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine preparation for recurrent oral ulcer, and also relates to a preparation method of the traditional Chinese medicine preparation. Background technique [0002] Oral ulcers, also known as "oral sores", are superficial ulcers that occur on the oral mucosa. The size can range from rice grains to soybeans, and they are round or oval. The pain caused by irritating food usually heals by itself in one to two weeks. Oral ulcers occur periodically and repeatedly, which are called "recurrent oral ulcers" in medicine. It can occur several times a year, or several times a month, and even new and old lesions appear alternately. Oral ulcers are characterized by recurring periodic attacks, which can occur in any part of the oral mucosa, and are more common in the oral cavity's lips, cheeks, soft palate, or gums, where single or mu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/02
Inventor 官爱忠蔡圳
Owner 辽宁省欣时代生物医药产业技术研究有限公司
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