Chinese medicinal preparation for treating recurrent oral ulceration
A traditional Chinese medicine preparation and oral ulcer technology, applied in the field of traditional Chinese medicine, can solve the problems of patients with heavy economic and mental burden, interference with diet and work and rest, and no specific treatment, etc., and achieve the effect of no toxic and side effects, not easy to relapse, and remarkable and reliable curative effect
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Embodiment 1
[0027] A traditional Chinese medicine preparation for recurrent oral ulcer, which is prepared from the following raw materials in parts by weight,
[0028] 20 parts of Qingdai, 18 parts of Baibu, 15 parts of Dijincao, 15 parts of Curcuma, 12 parts of Gualou,
[0029] Banzhilian 12 parts, Phellodendron 12 parts, Bellflower 10 parts, Gardenia 10 parts, Licorice 10 parts,
[0030] 10 parts of Astragalus, 10 parts of Ophiopogon japonicus, 7 parts of dark plum, 7 parts of Prunella vulgaris, 5 parts of Albizia juniper,
[0031] 5 parts of melon seeds, 5 parts of Uncaria, 3 parts of mulberry leaves,
[0032] Above-mentioned Chinese medicine preparation preparation method is:
[0033] (1) Take the bulk drug (proportioning unit: gram) of the above-mentioned parts by weight, and set aside;
[0034] (2) Take Baibu, Dijincao, Curcuma, Scutellaria barbata, Licorice, Prunella vulgaris, Albizia Albizia, and Uncaria, mix evenly, add 5 times the weight of water, soak for 30 minutes, boil wi...
Embodiment 2
[0038] zoology experiment
[0039] The acute toxicity test using mice showed that compared with the control group, there was no significant difference in the mice after administration. The experiment was observed for two consecutive weeks, and the general condition, food intake, drinking water, and weight gain of the mice were all normal. On the day of administration and within two weeks after administration, no animal died, suggesting that the drug has low acute toxicity and is safe for clinical use.
[0040] long-term toxicity test
[0041] Select 40 SD rats, half male and half male. Divide into 2 groups at random according to body weight, i.e. control group (equal dose of distilled water), Chinese medicine group of the present invention. 20 in each group, half male and half male. Each group of animals is administered intragastrically once a day, and after continuous administration for 1 month, each 10 of the matched group and the Chinese medicine group of the present inv...
Embodiment 3
[0043] clinical information:
[0044]Materials and methods: In order to further investigate the clinical curative effect and safety of the traditional Chinese medicine preparation of the present invention, we selected 70 cases of recurrent oral ulcer patients to conduct clinical observation on the curative effect of the medicine of the present invention. Randomly divided into a treatment group of 35 cases and a control group of 35 cases; aged 21-55 years, with an average age of 32 years, 33 cases of male patients and 37 cases of female patients, there were no significant differences in gender, age, course of disease, etc. between the two groups. Sexual differences are comparable.
[0045] standard constrain
[0046] (1) Repeated attacks of oral mucosal ulcers (more than 10 attacks per year), continuous attacks for more than 1 year -5 cases, exudation, hyperemia, edema and other manifestations were mainly seen.
[0047] treatment method
[0048] The treatment group was give...
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