Preparation method of 2-hydroxy-4-methylthio butyric acid metal chelate

Abstract

The invention relates to a preparation method of a 2-hydroxy-4-methylthio butyric acid metal chelate. The method comprises the following steps: performing a full reaction on hydrocyanic acid mixed gas prepared from an Andrussow method and methylthio propionaldehyde under the catalytic action of an alkali so as to obtain a 2-hydroxy-4-methylthio butyronitrile reaction system; performing a hydrolytic action on the 2-hydroxy-4-methylthio butyronitrile reaction system and sulfuric acid so as to obtain 2-hydroxy-4-methylthio butyric acid; adding an aqueous medium, a metallic compound and a crystallizing agent into the 2-hydroxy-4-methylthio butyric acid; regulating a pH value to reach 5 to 7 by using the alkali; heating to reach 60 DEG C to 90 DEG C; and performing cooling crystallization, thereby obtaining a 2-hydroxy-4-methylthio butyric acid metal chelate crystal. The method is low in production cost, wherein the obtained 2-hydroxy-4-methylthio butyric acid is easy to separate and purify, so that the 2-hydroxy-4-methylthio butyric acid with the high purity and the high yield can be obtained. Thus, the 2-hydroxy-4-methylthio butyric acid metal chelate which is further prepared from the 2-hydroxy-4-methylthio butyric acid has large crystalline particles.

Description

technical field [0001] The present invention is aimed at the field of chemical engineering, and relates to a method for preparing a metal chelate of 2-hydroxy-4-methylthiobutyrate, in particular to the preparation of 2-hydroxy-4-methylthiobutyrate on the basis of 2-hydroxy-4-methylthiobutyrate. 4-Methylthiobutanoic acid metal chelate method. Background technique [0002] 2-Hydroxy-4-methylthiobutyric acid is a methionine hydroxyl analogue, which has low toxicity, low rumen degradation rate, promotes the synthesis of rumen microorganisms, saves protein in the diet, improves the production performance of dairy cows, and improves animal health. It is the most economical and effective amino acid source for animals due to its production performance and immunity, reduced ammonia emissions, less environmental pollution, simple production process, and low price. Although methionine hydroxy analogs have the above advantages and are gradually replacing some expensive amino acids in t...

AI Technical Summary

Problems solved by technology

[0003] (1) It has a strong corrosive and pungent odor, and it is inconvenient to store, transport and use, so it is necessary to use an expensive special liquid feeding system;

[0004] (2) It is very viscous, and it is not easy to mix evenly in the feed premix;

[0005] (3) A large amount of heat is released when it comes into contact with water, causing the feed to heat up and ferment and become rancid during storage and transportation; the acidity is very high, with a pH of about 1, and it is easy to react with feed or other ingredients in the premixed feed. Nutrients cause damage

However, the production cost of this production process is higher

Specifically, in order to obtain high yield, all need purer hydrocyanic acid, and hydrocyanic acid is often excessive, and the additional rectification purification of hydrocyanic acid and excessive use all can cause the increase of cost, and the increase of this cost , especially on an industrial scale, will lead to huge economic losses; moreover, the unsuitability of the reaction system will also increase the burden of subsequent purification and separation, reducing the yield of the product

Images