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New functions and applications of trametes lactinea(Berk.)Pat. or extractives and trametenloic acid B

A technology for hydropinning acid and Trametes alba, which is applied to medical preparations containing active ingredients, applications, digestive systems, etc., can solve problems such as very few studies on Trametes alba

Active Publication Date: 2015-07-22
CHINA THREE GORGES UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are very few studies on Trametes magna at home and abroad

Method used

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  • New functions and applications of trametes lactinea(Berk.)Pat. or extractives and trametenloic acid B
  • New functions and applications of trametes lactinea(Berk.)Pat. or extractives and trametenloic acid B
  • New functions and applications of trametes lactinea(Berk.)Pat. or extractives and trametenloic acid B

Examples

Experimental program
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Effect test

Embodiment Construction

[0019] For the preparation method of the mycelium of Trametes dabai, extract of 3-hydropinic acid B, water extract of Trametes dabai, and 95% ethanol extract, please refer to the patent application for artificial cultivation method and application of Trametes dabai, the publication number is: 200810046969.7 .

[0020] 1. Anti-peptic ulcer test

[0021] (1) Inhibition of H + , K + -ATPase activity effect: Take normal Kunming mice, weighing 20-25g, do not fast, kill by cervical dislocation, sterilize in 75% alcohol for 5 minutes, dissect under sterile conditions, take out the stomach bag, and place it in cold PBS buffered saline solution middle. When taking the stomach, try to scrape off the coated protein and fat on the outer membrane. Use scissors to cut the extended part of the gastric bag from the lower opening, then turn the gastric bag over with tweezers, clamp the uncut end, wash away the food residue with PBS buffered saline solution, and store it temporarily in cold...

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Abstract

The invention relates to new functions and applications of trametes lactinea(Berk.)Pat. or extractives and trametenloic acid B. The substance trametes lactinea(Berk.)Pat has the functions of digestive gastric ulcer resistance, and nonulcerative-indigestion resistance through increasing of gastric motility. The trametes lactinea(Berk.)Pat. or the extractives and the trametenloic acid B have certain inbibitional effects on cell proliferation of gastric cancer cells, esophagus cancer cells Eca-109 and colorectal cancer cells LOVO, and has a wide range of research value and mass production and edible value in dugs for digestive system and gastric cancer resisting and the like.

Description

technical field [0001] The application relates to the use of mycelium of Trametes dabai or the extract of Trametes dabai, and 3-hydropinemic acid B, especially its use in pharmacy and health food. Background technique [0002] Trametes lactinea (Berk.) Pat. is a large fungus of the genus Trametes lactinea in the order Polyporaceae [1] In the experiment, Trametes grandis was isolated from pepper, a common food of the Tujia people in Tuli, and was identified as Trametes grandis by Mr. Wang Shaobo. There are very few studies on Trametes magna at home and abroad. In recent years, studies on Trametes major have shown that the extract of Trametes major has good immune enhancement and anti-tumor effects. Contents of the invention [0003] Use electron ionization mass spectrometer (VG Analytical70-250S, 70eV) to measure the molecular weight of the extract of Trametes albus, and obtain the NMR data of the extracted compound as [0004] Table 1 The NMR data of Trametes maxima ext...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/06A23L1/29A61P1/04A61P1/14A61P35/00A61K31/575A23L33/00
Inventor 汪鋆植张巧银贺海波罗华军黄年玉孙文军金蕾邹坤
Owner CHINA THREE GORGES UNIV
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