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Method for coating esophageal stent through melt electrospinning

A melt electrospinning, esophagus technology, used in textiles and papermaking, filament/thread forming, non-woven fabrics, etc., to reduce irritation and foreign body sensation, and increase biocompatibility.

Inactive Publication Date: 2013-07-31
BEIJING UNIV OF CHEM TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the present invention can spin smoothly without using solvent, it can solve a series of problems caused by the use of solvent in solution electrospinning

Method used

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  • Method for coating esophageal stent through melt electrospinning
  • Method for coating esophageal stent through melt electrospinning
  • Method for coating esophageal stent through melt electrospinning

Examples

Experimental program
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Embodiment Construction

[0014] What the present invention adopts is a kind of method of melt electrospinning to carry out esophageal stent coating, the schematic diagram is as follows figure 1 Melt electrospinning device and figure 2 As shown in the stent coating device, the melt electrospinning device mainly includes a capillary (1), a nozzle (2), and a tight connection connecting the nozzle (2) and the barrel (5) covering the electromagnetic heating coil (4). Fixing screw (3), piston shaft with end cap (6), temperature sensor for controlling melt temperature (7), capillary fastening screw (8) connecting capillary (1) with nozzle (2), bracket The coating device mainly includes a metal bracket (9), a metal slip ring (10) connected to the positive pole of the high-voltage electrostatic generator (16), an insulating rod (11) with metal plating on the surface, and a motor base for fixing the linear stepping motor (14) (12) and cylindrical Phillips head screw (13), the guide rod (15) that controls the ...

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Abstract

The invention discloses a method for coating an esophageal stent through melt electrospinning and belongs to the fields of medical instruments and electrospinning. Devices adopted by the method comprise a melt-electrospinning device, a stent coating device and the like, wherein the melt-electrospinning device comprises a capillary tube, a nozzle, a heating ring, a hopper, a piston shaft with an end cover, a temperature sensor, a high-voltage electrostatic generator and the like; the stent coating device comprises a stent, a metal-coated insulating rod, a slip ring, a guide rod and a linear stepping motor; and a polymer can be thermoplastic resin used in a living body; and a spinning raw material can be polymer particles, or powder, or slices or melt. The method can be used for melt-electrospinning coating of metallic or nonmetallic stent.

Description

technical field [0001] The invention relates to a method for coating an esophageal stent by melt electrospinning, and belongs to the fields of medical equipment and electrospinning. Background technique [0002] Most patients with advanced esophageal cancer lose the opportunity for surgery. Long-term dysphagia causes severe malnutrition. The tumor destroys the esophageal wall tissue and forms an esophagus-tracheal fistula, making the patient unable to eat. With the development of the esophageal stent (Stent) implantation technology, the covered stent effectively controls the growth of the tumor into the lumen, and seals the fistula, which solves the patient's difficulty in swallowing and the pain of eating and coughing. The patient's quality of life improves the patient's confidence in overcoming the disease. [0003] The coated esophageal stent is made of high-elastic stainless steel or nickel-titanium memory alloy for medical surgical implantation after special process dr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): D04H1/728D01D5/00
Inventor 刘勇陈志远宋天丹李秀红刘月星刑长民孙国林郭鸿霖
Owner BEIJING UNIV OF CHEM TECH
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