Preparation method of titanium foam used for cortical bone

Abstract

The invention relates to a preparation method of titanium foam used for cortical bone, which comprises the following steps: 1) selecting titanium powder and a pore forming agent and uniformly mixing to obtain a preliminary mixture, wherein the mass fraction ratio of the titanium powder and the pore forming agent is 67.2-72.28-32.8; 2)performing unidirectional compacting on the preliminary mixture to obtain the raw pressed compact, wherein the unidirectional pressure is 150-300MPa and the dwell time is 1-2 minutes; and 3)placing the raw pressed compact in a vacuum carbon tube furnace, sintering for 2 hours at the temperature of 1200-1300 DEG C to remove the pore forming agent, and cooling in furnace to obtain the titanium foam. The titanium foam compressive strength is close to human body cortical bone compressive strength, and has long service life, young modulus of the titanium foam and the young modulus of human body cortical bone are matched, stress shield phenomenon is effectively avoided, the long time fixation of an implantation material is realized, and the aperture dimension is in the allowed scope of the cortical bone, and the preparation method of titanium foam is in favor of new bone growth and nutrients conveying.

Description

technical field [0001] The invention relates to the technical field of foamed titanium materials, in particular to a method for preparing foamed titanium for cortical bone. Background technique [0002] In recent years, bone defect repair materials have become one of the biomedical materials with the greatest clinical demand. Traditional bone substitute materials are dense metals or alloys, such as cobalt-nickel alloys, stainless steel, titanium-based alloys, etc. Among them, titanium and titanium alloys have been more widely used than other metal implant materials, which is mainly due to the excellent mechanical properties, excellent corrosion resistance, and superior biocompatibility of titanium and titanium alloys ( Biocompatibility refers to a property of the response of living body tissues to inactive materials). However, compared with human bone with a porous structure, titanium and titanium alloys face two problems as implant materials: (1) The Young’s modulus of ti...

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Problems solved by technology

However, compared with human bone with a porous structure, titanium and titanium alloys face two problems as implant materials: (1) The Young’s modulus of titanium and titanium alloys does not match the modulus of bone, resulting in stress shielding ( The shunting phenomenon of the physiological stress of the bone by the fixing material is called the stress shielding of the bone by the fixing material); (2) The dense structure is not conducive to the growth of bone tissue, which reduces the service life of titanium and titanium alloy implant materials

For the first time, M. Bram et al. used powder metallurgy to add urea as a pore-forming agent to prepare titanium foam with a pore size of 100-2500 μm and a porosity of 60-80%, and studied the pore geometry of the sample. (shape and pore size distribution); afterward, people continue to use this method to manufacture titanium foam, and study the compression behavior of titanium foam with different porosity, the relationship between Young's modulus and relative density, energy absorption characteristics; the size of pore-forming agent, the addition However, there is still little research on the use of urea as a pore-forming agent to design and prepare titanium foam that meets the requirements of bone substitute materials.

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