Traditional Chinese cataplasm for traumatic injury as well as preparation method thereof

Abstract

The invention discloses a traditional Chinese cataplasm for traumatic injury. The traditional Chinese cataplasm for traumatic injury is prepared from radix gaultheriae, largespike woodnettle root, asiatic toddalia root, Pink Reineckea Herb, Oxalis corniculata L, Chinese Alangium, Polygonum cuspidatum, pseudo-ginseng, camphor, borneol, menthol, glycerol, sodium polyacrylate, sodium carboxymethylcellulose, gelatin, sodium carbonate, lidocaine and purified water. According to the cataplasm refined by Chinese herb extracts based on water soluble high-molecular compounds as a matrix, the compatibility and affinity of medicine and skin are improved and transdermal absorption is enhanced; in addition, the drug loading capacity is large, the bioavailability is high, the moisturizing period is long and the sweat-resistance is strong. The cataplasm can be uncovered and pasted repeatedly, is small in irritation, and does not cause skin allergy.

Description

technical field [0001] The invention relates to a traditional Chinese medicine catarrh ointment for bruises and a preparation method thereof, belonging to the field of pharmaceutical technology. Background technique [0002] The rapid development of today's science and technology supports the high-speed operation of all walks of life in society, and it also shows the important position of science and technology in the field of pharmaceutical preparations. Various unprecedented new drug dosage forms have come out one by one, bringing many benefits to patients in various treatments; but At present, many drugs are mainly administered orally, and most drugs undergo the first-pass effect in the liver or degrade in the gastrointestinal tract after oral administration, which reduces the efficacy of the drug; however, a drug-based active ingredient mixed with a suitable matrix After uniformity, the plaster made by coating on the backing material, that is, a kind of external plaster,...

AI Technical Summary

Problems solved by technology

Modern pharmacological studies have proved that Compound Shangfuning Ointment has the effects of promoting blood circulation and removing blood stasis, reducing swelling and relieving pain, and has definite curative effect on limb pain caused by various traumatic injuries. The existing method of producing Compound Shangfuning Ointment generally uses pharmaceutical The method on the standard (WS-10989 (ZD-0989)-2002), the preparation recorded in the above standard is a rubber plaster, the rubber plaster made by the above method is easy to cause pain when peeled off, and has certain irritation and allergies to the skin Sex, especially for patients with wounds can not be used

In addition, since the raw material of Compound Shangfuning Ointment contains methyl salicylate, methyl salicylate plays an analgesic effect in the prescription, but methyl salicylate has a local irritation effect on the skin, so if it is applied locally Prone to blisters or rupture

For the above reasons, Compound Shangfuning Ointment is only suitable for closed injuries, not for open injuries.

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