Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Optical biological detection method based on tri-doped lithium niobate crystal

A technology of biological detection and lithium niobate, which is applied in the direction of phase influence characteristic measurement, etc., can solve the problems of long writing grating time and affecting grating application, etc., and achieve fast real-time detection, high detection sensitivity, and low cost effects

Active Publication Date: 2013-03-20
TAIYUAN UNIV OF TECH
View PDF1 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this method also has this problem. It takes too long to write the grating, which takes hundreds of minutes, which will seriously affect the application of the grating in high-sensitivity, real-time detection processing.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Optical biological detection method based on tri-doped lithium niobate crystal
  • Optical biological detection method based on tri-doped lithium niobate crystal

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] The specific implementation manners of the present invention will be further described below.

[0032] Implementation of an optical biosensor detection method provided by the present invention, including the method of all-optical writing of a stable, non-volatile waveguide grating on a triple-doped lithium niobium crystal used in the method of the present invention, binding biometric recognition on the grating The molecule reacts specifically with the target molecule to change the optical properties, and then quantitatively detect the concentration of the target molecule. The specific detection method is carried out according to the following steps:

[0033] (1) Formation of the waveguide: Using the method of high-temperature titanium internal diffusion, the optical waveguide is formed on the surface of the z-cut y-propagated triple-doped Hf, Fe, Mn lithium niobate crystal, and the crystal surface is sequentially subjected to electron beam evaporation, flame hydrolysis, ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an optical biological detection method based on tri-doped lithium niobate crystal. The optical biological method comprises the steps of: forming a waveguide grating substrate base on the tri-doped lithium niobate crystal, forming a waveguide on the substrate, forming a holographic bragg grating on the waveguide, forming a biological recognition molecule on the holographic bragg grating, forming a target molecule on the biological recognition molecule, forming waveguide grating reflection light wavelength change on the target molecule, and forming biomolecule concentration on the waveguide grating reflection light wavelength change. The method has the characteristic of full-gloss fast writing in a non-volatile holographic grating, and simultaneously realizes low cost, and high-precision, multi-flux, quick quantitative detection of the biological molecule, is applicable to quantitatively detecting micro concentration of harmful components, pesticide residue, narcotics and the like in the food, and has an extensive market prospect.

Description

technical field [0001] The invention relates to an optical biological detection method, in particular to an optical biological detection method based on a non-volatile holographic Bragg grating of triple-doped lithium niobate crystal. Background technique [0002] In 1967, Updike and Hicks assembled the glucose oxidase (GOD) immobilized membrane and oxygen electrode together to make the first biosensor based on the glucose enzyme electrode. After that, various biosensors for biological detection, such as Thermosensitive biosensors, field effect tube biosensors, piezoelectric biosensors, optical biosensors, acoustic channel biosensors, enzyme electrode biosensors, mediator biosensors, etc. are widely used in production and life. Among them, the optical-biosensor is a powerful detection and analysis tool, and it is one of the most widely studied and fastest-growing biosensors. [0003] According to different optical detection principles, it can be divided into surface plasm...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/41
Inventor 李晓春崔彩娥张玲玲于化忠
Owner TAIYUAN UNIV OF TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com