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Cough relieving and sore-throat relieving cataplasm and preparation method thereof

A formulation and coating technology, which is applied in the direction of pharmaceutical formulations, medical preparations with no active ingredients, medical preparations containing active ingredients, etc., can solve the problems of no external use of the two medicines, no pharyngitis and other problems, and achieve Convenient and comfortable application, good drug stability, and strong sustained-release effect

Inactive Publication Date: 2013-02-27
DONGGUAN MATHEMATICAL ENG ACAD OF CHINESE MEDICINE GUANGZHOU UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no report in the literature on the prescription of traditional Chinese medicine for treating pharyngitis with Qingtiankui combined with puffball, and there is no report of the two medicines being used together for external use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Take 10g of Celestia chinensis and 4g of Puffball, grind them with a Chinese medicine high-speed pulverizer respectively, pass through a 60-mesh sieve, and the sieving rate of the medicinal powder reaches more than 95%. Mesh sieve, the sieving rate reaches more than 90%, to obtain medicinal material powder, for subsequent use.

[0031] Take 3g of carbomer, add 57ml of water to swell overnight to obtain 5% carbomer paste, set aside. Take medicinal material powder, add about 20ml of distilled water, stir well, add carbomer paste, stir at 300 rpm for 30 minutes, as phase I, and set aside; take another 50ml of glycerin, add 0.3g of glycerol and 10g of sodium polyacrylate in turn, Stir while adding, and stir at 400 rpm for 20 minutes after the addition, as phase II, for later use; take 5g of polyvinylpyrrolidone, add an appropriate amount of distilled water 20ml, and after fully dissolved, add 0.3g of tartaric acid and 0.5g of ethylparaben in sequence, and add While stirrin...

Embodiment 2

[0034] Take 5g of Qingtiankui and 3g of puffball, combine them together and grind them with a Chinese medicine high-speed pulverizer, pass through a 40-mesh sieve, and the sieving rate of the medicinal powder will reach more than 95%, continue to pulverize in the superfine pulverizer, pass through a 300-mesh sieve, and the sieving rate will reach 95%. Reach more than 95%, get medicinal material powder, standby.

[0035]Take 2g of carbomer, add 38ml of water to swell overnight to obtain 5% carbomer paste, set aside. Take the medicinal material powder, add about 15ml of distilled water, stir well, add carbomer paste, 3g of silicon dioxide, stir for 20 minutes at 300 rpm, and use it as Phase I for later use; take another 20ml of glycerin, add 0.15g of aluminum glycolate, poly Add 6g of sodium acrylate, stir while adding, and stir at 300 rpm for 30 minutes after adding, as phase II, for later use; take 3g of polyvinylpyrrolidone and 3g of sodium carboxymethylcellulose, add appropr...

Embodiment 3

[0038] Take 15g of blue skyflower and 3g of puffball, add 200ml of water to soak for 30 minutes, then reflux for extraction for 1 hour, filter, add 150ml of water to the dregs, reflux for 1.5 hours, filter, combine the filtrates, concentrate under reduced pressure to a relative density of 1.20 at 60°C Clean the ointment and set aside.

[0039] Take 1.5g of carbomer, add the extraction clear paste to swell overnight to obtain carbomer paste, add 2g of silicon dioxide and appropriate amount of water, stir at 300 rpm for 15 minutes, and use it as phase I for later use; take another 18ml of glycerin, add glycerol in turn Aluminum 0.1g, sodium polyacrylate 4g, stir while adding, and stir at 400 rpm for 20 minutes after the addition, as phase II, for later use; take 2g of polyvinylpyrrolidone, 1.5g of sodium carboxymethylcellulose, add 20ml of distilled water, fully After dissolving, add 0.1 g of tartaric acid and 0.3 g of ethylparaben in turn, and stir while adding. After all the m...

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PUM

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Abstract

The present invention relates to the technical field of traditional Chinese medicine preparation, and provides a cough relieving and sore-throat relieving cataplasm and a preparation method thereof, wherein the cataplasm adopts ford nervilia leaf and puff-ball as raw materials, and is prepared by adopting a matrix formula and the preparation method provided by the present invention, the traditional Chinese medicine raw materials comprise, by weight, 5-15 parts of ford nervilia leaf and 3-10 parts of puff-ball, and the prepared cataplasm has characteristics of high drug loading, good drug stability, good stickiness, no skin residue, no irritation allergy on skin, convenient and comfortable applying, and the like, can be clinically applied on corresponding meridian points of human body, has functions of lung heat clearing, cough relieving and sore-throat relieving, and is provided for treatments of cough with lung heat, sore throat, and the like.

Description

technical field [0001] The patent of the present invention relates to a traditional Chinese medicine patch and a preparation method thereof, in particular to a traditional Chinese medicine patch for relieving cough and pharynx catarrh and a preparation method thereof for treating lung-heat cough, sore throat, and tonsillitis. Background technique [0002] Catapult is a kind of external plaster, which is a new dosage form of transdermal drug preparation. It refers to the preparation of medicinal material extracts, medicinal materials or chemical drugs mixed with a suitable hydrophilic matrix and coated on the backing material. Made plaster. The characteristics of transdermal drug delivery: (1) The transdermal drug delivery system can avoid the first-pass effect of the liver and the inactivation of drugs in the gastrointestinal tract, and the absorption of drugs is not affected by gastrointestinal factors. Reduce individual differences in medication. (2) Maintain a constant ...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K47/38A61K9/70A61P11/14A61P11/04
Inventor 谢友良蒋东旭易智彪詹丽玲王德杭赖小平
Owner DONGGUAN MATHEMATICAL ENG ACAD OF CHINESE MEDICINE GUANGZHOU UNIV OF CHINESE MEDICINE
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