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Bacteria-resisting, inflammation-diminishing and itching-relieving traditional Chinese medicine composition and preparation method and application thereof

An antibacterial, anti-inflammatory and composition technology, applied in the directions of antibacterial drugs, drug combinations, antifungal agents, etc., can solve the problems such as the inability of antibiotics to meet clinical needs and the increased frequency of drug resistance, so as to improve the body's immune function, achieve significant curative effects, and avoid toxic side effects

Active Publication Date: 2012-12-26
百润(中国)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in recent years, people's long-term and extensive use of antibiotics has led to continuous enhancement of bacterial resistance, and the frequency of drug resistance has gradually increased, so that conventional antibiotics cannot meet clinical needs

Method used

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  • Bacteria-resisting, inflammation-diminishing and itching-relieving traditional Chinese medicine composition and preparation method and application thereof
  • Bacteria-resisting, inflammation-diminishing and itching-relieving traditional Chinese medicine composition and preparation method and application thereof
  • Bacteria-resisting, inflammation-diminishing and itching-relieving traditional Chinese medicine composition and preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Prescription 1: Prepare 20g of Cnidium chinensis, 20g of Polygonum cuspidatum, 20g of Sophora flavescens, 10g of dandelion, 10g of white moss bark, 10g of Baibu, 5g of Cortex Phellodendri, 5g of Angelica dahurica, 5g of alum, 3g of cloves, and 30g of Vitex bark. Reflux extraction according to the prescription (except alum and Vitex bark), filter, add alum and Vitex bark extract (70% alcohol twice) to the filtrate, concentrate to 1ml:0.5g to 1ml:1g, After the liquid is allowed to cool, slowly add ethanol while stirring to reach the specified alcohol content (70-80%), airtightly refrigerate for 48 hours, filter, recover ethanol from the filtrate, add water to dissolve and filter to obtain a refined liquid. Finally, it works in liquid form. 1ml:1g means that every 1ml of liquid medicine is equivalent to 1g of prescription crude drug.

[0017] Prescription 2: The composition of the traditional Chinese medicine raw materials of the above-mentioned antibacterial, anti-inflam...

Embodiment 2

[0020] Embodiment 2, the extraction and refining method of Chinese medicine compound of the present invention

[0021] The traditional Chinese medicine composition of the present invention can be prepared by conventional preparation methods of traditional Chinese medicines. Optimal use of water extraction and alcohol precipitation.

[0022] 1. Water extraction and alcohol precipitation

[0023] The water extraction and alcohol precipitation method refers to the method of adding ethanol to the concentrated solution of traditional Chinese medicine to achieve different alcohol content, and the solubility of certain medicinal components in the alcohol solution is reduced and precipitated, and the water extract is refined after solid-liquid separation. The specific operation process is: concentrate the water extract of the traditional Chinese medicine compound of the present invention to 1:1 (g:ml), let the liquid cool, slowly add ethanol while stirring to reach 70% alcohol conten...

Embodiment 3

[0028] One, Chinese medicine compound of the present invention is carried out antibacterial effect verification:

[0029] 1. Preparation

[0030] 1.1 Culture medium preparation: According to different strains, prepare various corresponding culture medium

[0031] 1.2 Other Items

[0032] Oxford cup, tweezers, smear stick, saline solution, clean test tube, inoculation loop, pipette tip, waste container, positive drug, test drug, alcohol lamp, pipette gun, different bacterial species (Staphylococcus aureus, white grape coccus, Pseudomonas aeruginosa, Escherichia coli, Candida albicans, Lactobacillus standard).

[0033] 1.3 Strain activation

[0034] Take a clean test tube, add an appropriate amount of MH broth medium (prepared according to the ratio of 2.7g dry powder to 100ml liquid medium), and sterilize it under high pressure. After cooling on the clean bench, take an appropriate amount of bacteria into the test tube with an inoculation loop, and mix well. Observe the res...

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Abstract

The invention relates to a traditional Chinese medicine composition, and in particular relates to a bacteria-resisting, inflammation-diminishing and itching-relieving traditional Chinese medicine composition and a preparation method and application thereof. The traditional Chinese medicine composition avoids having toxic and side effects on human bodies and has the functions of resisting bacteria, diminishing inflammation, relieving itching, regulating vaginal flora disturbance, increasing the quantity of vaginal lactobacillus and improving the immune functions of the bodies. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 20-30 parts of fructus cnidii, 20-30 parts of giant knotweed rhizome, 20-30 parts of radix sophorae flavescentis, 10-20 parts of dandelions, 10-15 parts of densefruit pittany root-bark, 10-20 parts of radix stemonae, 5-10 parts of amur corktree bark, 5-10 parts of dahurian angelica root, 5-10 parts of white alum, 3-6 parts of cloves and 30-50 parts of golden larch bark. The traditional Chinese medicine composition has the functions of clearing away heat and toxic materials, dispelling wind and eliminating dampness and killing parasites to relieve itching and can be used on health products such as sanitary towels in aid of gynecological disease treatment.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to an antibacterial, anti-inflammatory and antipruritic traditional Chinese medicine composition and a preparation method and application thereof. Background technique [0002] With the continuous emergence of various antibiotics represented by penicillin, bacterial infectious diseases have been effectively controlled, making antibiotics a powerful weapon for humans to resist pathogenic bacterial infections. However, in recent years, people's long-term and extensive use of antibiotics has led to continuous enhancement of bacterial resistance, and the frequency of drug resistance has gradually increased, so that conventional antibiotics cannot meet clinical needs. With the important changes in the global disease spectrum and medical model, our country is gradually in line with the world economy, culture and drug use level. Due to the impact of drug resistance, people are...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61P31/04A61P31/10A61P17/04A61L15/44A61K33/06
Inventor 陈大鹏
Owner 百润(中国)有限公司
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