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Oldenlandia liver-tonifying and toxicity-eliminating particles and preparation method thereof, as well as detection method

A detection method and liver-benefiting technology, applied in measuring devices, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of not having a set of strict and reliable quality inspection standards

Inactive Publication Date: 2012-10-03
GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In addition, there is currently no set of strict and reliable quality testing standards for liver-enhancing and detoxifying drugs

Method used

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  • Oldenlandia liver-tonifying and toxicity-eliminating particles and preparation method thereof, as well as detection method
  • Oldenlandia liver-tonifying and toxicity-eliminating particles and preparation method thereof, as well as detection method
  • Oldenlandia liver-tonifying and toxicity-eliminating particles and preparation method thereof, as well as detection method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0263] Example 1: Weigh 20kg of Hedyotis diffusa, 10kg of Ganoderma lucidum, 8kg of Polygonatum, 10kg of Astragalus, 8kg of Alisma, 8kg of cooked rhubarb, 4kg of Cistanche, 10kg of turtle shell, 8kg of Schisandra chinensis, 8kg of ginkgo leaves and 6kg of licorice; Schisandra chinensis and Alisma chinensis medicinal materials were extracted 3 times with 70% ethanol in an amount of 6 times, each time for 2 hours, filtered, the alcohol extract was concentrated under reduced pressure at 70°C to a density of 1.2 (measured by a pycnometer), and the thick extract was dried under reduced pressure at 80°C After 36 hours, a dry paste was obtained, which was crushed through a No. 3 sieve to obtain an alcohol-extracted powder. Mix the other 8 raw materials with alcohol extraction dregs, add 6 times the amount of water to soak for 0.5h, add 6 times the amount of water and decoct for 0.5h, add 12 times the amount of water in total, decoct three times, the decoction time is: 3h, 3h and 1h, ...

Embodiment 2

[0264] Example 2: Take Hedyotis diffusa 5kg, Ganoderma lucidum 2kg, Polygonatum 1kg, Astragalus 2kg, Alisma 1kg, cooked rhubarb 1kg, Cistanche 1kg, turtle shell 2kg, Schisandra chinensis 1kg, ginkgo leaf 1kg and licorice 1kg; cooked rhubarb, Schisandra chinensis and Alisma chinensis were extracted with 6 times the amount of 70% ethanol for 3 times, each time for 2 hours, filtered, the alcohol extract was concentrated under reduced pressure at 70°C to a density of 1.2, and the thick extract was dried under reduced pressure at 80°C for 36 hours to obtain a dry paste. Crush and sieve to obtain alcohol-extracted powder; mix the remaining 8 raw materials and alcohol-extracted drug residues, add 6 times the amount of water to soak for 0.5 hours, add 6 times the amount of water and fry for 0.5 hours, add 12 times the amount of water in total, decoct three times, and decoct The cooking time is: 3h, 3h and 1h respectively, concentrated under reduced pressure at 85°C to a density of 1.2,...

Embodiment 3

[0265] Example 3: Weigh 25kg of Hedyotis diffusa, 15kg of Ganoderma lucidum, 10kg of Polygonatum, 15kg of Astragalus, 10kg of Alisma, 10kg of cooked rhubarb, 5kg of Cistanche, 15kg of turtle shells, 10kg of Schisandra chinensis, 10kg of ginkgo leaves and 6kg of licorice; Schisandra chinensis and Alisma chinensis were extracted with 6 times the amount of 70% ethanol for 3 times, each time for 2 hours, filtered, the alcohol extract was concentrated under reduced pressure at 70°C to a density of 1.2, and the thick extract was dried under reduced pressure at 80°C for 36 hours to obtain a dry paste. Crush and sieve to obtain alcohol-extracted powder; mix the remaining 8 raw materials and alcohol-extracted drug residues, add 6 times the amount of water to soak for 0.5 hours, add 6 times the amount of water and fry for 0.5 hours, add 12 times the amount of water in total, decoct three times, and decoct The cooking time is: 3h, 3h and 1h respectively, concentrated under reduced pressur...

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Abstract

The invention provides oldenlandia liver-tonifying and toxicity-eliminating particles and a preparation method thereof, as well as a detection method. The particles comprise the following raw materials by weight: 5 to 25kg of oldenlandia, 2 to 15kg of lucid ganoderma, 1 to 10kg of sealwort, 2 to 15kg of astragalus mongholicus, 1 to 10kg of rhizoma alismatis, 1 to 10kg of prepared Chinese rhubarb, 1 to 5kg of cistanche, 2 to 15kg of turtle shell, 1 to 10kg of Chinese magnoliavine fruit, 1 to 10kg of gingko leaves, and 1 to 6kg of liquorice. The preparation method comprises the following steps of: extracting the components, and adding proper soluble starch and Aspartame with 80 percent ethanol serving as a wetting agent. Aiming at the defects in the prior art, the preparation process of the oldenlandia liver-tonifying and toxicity-eliminating particles is optimized, so that a curative effect of the particles to viral hepatitis is remarkable, and a systematic, complete and effective component identification and content determination method is established, and the quality of the medicament can be effectively controlled, so that the clinical curative effect of the particles can be guaranteed.

Description

technical field [0001] The invention relates to a Baihua Yigan Paidu granule, a preparation method and a detection method thereof, and belongs to the technical field of traditional Chinese medicines. Background technique [0002] The liver is an important detoxification organ. After a series of chemical reactions in the liver, various toxins become non-toxic or low-toxic substances. Once the liver changes, it will cause liver disease, which is extremely harmful. Common liver diseases include hepatitis B, hepatitis A, hepatitis C, cirrhosis, fatty change, liver cancer, alcoholic liver and so on. Therefore, the traditional Chinese medicine preparation with the effect of benefiting the liver and detoxifying can play a good role. [0003] The patent application with the application number "200410022730.8" discloses a drug for nourishing the liver and detoxification and its preparation method. The preparation method is to decoct and extract all 11 medicinal materials with water;...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61K9/16G01N30/02G01N30/90A61P1/16A61K35/56A61K35/586
Inventor 王祥培靳凤云张欣
Owner GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE
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