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Honeysuckle throat clearing tablets and preparation method thereof

A Yinhua throat clearing and tablet technology, which is applied in pill delivery, pharmaceutical formulations, medical preparations with non-effective ingredients, etc., can solve problems such as unsatisfactory, poor compliance with medication, and affect treatment effects, etc., to improve appearance, good health, etc. Therapeutic effect, the effect of increasing the disintegration rate

Active Publication Date: 2012-09-12
GENERAL HOSPITAL OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] For the treatment of chronic pharyngitis, Western medicine mainly uses antibiotics, iodine-coated glycerin, inhalation of tincture of benzoin and laser therapy. Although there is a certain effect, it is not ideal.
As a routine and effective external treatment method for acute pharyngitis, nebulization inhalation is also widely used in clinical practice, but because nebulization inhalation needs to be carried out in hospitals, patients are often limited by time and space during treatment, resulting in poor compliance with medication , affecting the therapeutic effect of

Method used

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  • Honeysuckle throat clearing tablets and preparation method thereof
  • Honeysuckle throat clearing tablets and preparation method thereof
  • Honeysuckle throat clearing tablets and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] The preparation of embodiment 1 Yinhua Qingyan tablet

[0059] 1. Material

[0060] 1.1 Instruments DP / 30 single-punch tablet press (Beijing Sinopharm Longli Technology Co., Ltd.); ZB-1D intelligent disintegration instrument (Tianda Tianfa Technology Co., Ltd.); electric heating constant temperature drying oven GZX-DH-50×55-B5 ( Shanghai Yuejin Medical Instrument Factory); HH / S Electric Heating Constant Temperature Water Bath (Jiangsu Shazhou Medical Instrument Factory); Standard Inspection Sieve (manufactured by Shangyu Yarn Sieve Factory in Zhejiang Province).

[0061] 1.2 Excipients Starch (batch number: 10121501, Liaoning Dongyuan Pharmaceutical Co., Ltd.), dextrin (batch number: 10112501, Liaoning Dongyuan Pharmaceutical Co., Ltd.), lactose (batch number: 8509100312, Liaoning Dongyuan Pharmaceutical Co., Ltd.), carboxymethyl Carboxymethylsrarch sodium (CMS-Na, batch number: 20110309, Huzhou Zhanwang Pharmaceutical Co., Ltd.), cross-linked polyvinylpyrrolidone (cr...

Embodiment 2

[0122] Example 2 Pharmacodynamic study of Yinhua Qingyan tablet

[0123] 1. Material

[0124] 1.1 Animals Wistar rats, half male and half female, weighing 200±20g (provided by the Experimental Animal Center of PLA General Hospital).

[0125] 1.2 Drugs and Reagents Caoshanhu Buccal Tablets (produced by Jiangxi Jiangzhong Pharmaceutical Factory. Ganwei Pharmaceutical Zhunyu (1996) No. 07300l) batch number: 20100412; Yinhua Qingyan Tablets (provided by the preparation room of PLA General Hospital) batch number: 20100625; ammonia water ( Beijing Chemical Plant) batch number: 20090401, concentration 25% to 28%; chloral hydrate (produced by the General Hospital of the Chinese People's Liberation Army, ZZZ (2006) B01043) batch number: 20100408.

[0126] 1.3 Instrument throat sprayer: manufactured by Taizhou Huichun Medical Instrument Co., Ltd., Sutai Food and Drug Administration (Quasi) No. 1050003, 2010, XE-2100 blood cell analyzer (made in Japan), blood collection tube, self-made...

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Abstract

The invention belongs to the field of medicinal preparations, and particularly relates to a honeysuckle throat clearing formula and a tablet preparation method thereof. The honeysuckle throat clearing tablets contain medicament extract and pharmaceutically acceptable diluting agent, lubricating agent and disintegrating agent. The honeysuckle throat clearing tablets prepared by the invention have a better treatment effect on acute pharyngitis.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to a Yinhua Qingyan formula and a method for preparing tablets thereof. Background technique [0002] Modern medicine believes that chronic pharyngitis is mostly caused by recurrent acute pharyngitis, mouth breathing due to long-term nasal obstruction, dental caries, tobacco and alcohol addiction and other bad living habits, harmful gas stimulation, systemic diseases, such as upper respiratory tract infection, digestive system disease, endocrine Disorders, diabetes, anemia, etc. can all induce this disease. Pathological changes are divided into three types: chronic simple pharyngitis, chronic hypertrophic pharyngitis and atrophic pharyngitis. [0003] Traditional Chinese medicine believes that chronic throat inflammation is mainly caused by wind-heat and throat numbness, pathogenic heat damages yin, lung and kidney yin deficiency, chronic burning of asthenia, ...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61K9/20A61K47/36A61K47/38A61P11/04
Inventor 徐风华郝爱真王欢欢
Owner GENERAL HOSPITAL OF PLA
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