Implants comprising biodegradable metals and method for manufacturing the same

一种制造方法、植入物的技术，应用在骨植入物、脊柱植入物、关节植入物等方向，能够解决介面粘着强度限制等问题，达到优异介面强度、生物降解率轻易、优异介面粘着强度的效果

Inactive Publication Date: 2012-06-27
U & I INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, although many efforts have been made in the past to improve coating technology, there are still some limitations in the interfacial adhesion strength of implants and their coating materials.

Method used

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  • Implants comprising biodegradable metals and method for manufacturing the same
  • Implants comprising biodegradable metals and method for manufacturing the same
  • Implants comprising biodegradable metals and method for manufacturing the same

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0053] Implant material made from pure magnesium

[0054] Manufacturing costs also increase exponentially due to the higher purity when high purity materials with low dopant content are used. Therefore, its commercial value deteriorates. In each example, in order to determine the dopant concentration of magnesium that can be used as an implant material, different amounts of iron and nickel were added during the manufacture of magnesium, and its corrosion characteristics were evaluated (hereinafter, the dopant concentration is 0.01% or less Magnesium, known as pure magnesium or 100% magnesium). First, each magnesium with different dopant concentrations is filled in a stainless steel (SUS304) crucible with an inner diameter of 50 mm, wherein ultra-pure reagent-grade magnesium (99.9999%) is mixed with the following iron and nickel in different contents: (1) 400ppm (0.04%) and 10ppm (0.001%); (2) 70ppm (0.007%) and 5ppm (0.0005%); (3) 10ppm (0.001%) and 35ppm (0.0035%). Next, i...

example 2

[0056] Manufacture of magnesium calcium alloy

[0057] A magnesium alloy is made by mixing magnesium and calcium. Among them, pure magnesium (purity 99.995%) containing dopant 10ppm (0.001%) iron and 35ppm (0.0035%) nickel is mixed with 0.8%, 5%, 10.5%, 23%, and 33% calcium respectively, and The mixed materials were respectively charged into a stainless steel (SUS304) crucible with an inner diameter of 50 mm. Subsequently, in order to prevent the magnesium alloy in the crucible from coming into contact with the air, the temperature of the crucible was increased to a range of about 700°C to 1000°C with a resistance heater while flowing argon gas around the periphery of the crucible to melt the magnesium alloy. The completely molten magnesium alloy is quenched to produce a solid magnesium alloy. The crucible is stirred to mix the elements in the molten magnesium alloy with each other. In addition, during quenching, the crucible is immersed in water to rapidly cool and harden ...

example 3

[0060] Manufacturing of Mg-Ca Alloy by Rapid Quenching by Gas Blowing

[0061] First, a heater is used to melt the magnesium alloy, and then the molten magnesium alloy is injected into a small hole with a diameter of about 3 mm by the spraying method using argon gas, and then solidified to form a rapidly quenched magnesium alloy Material. If this method is used, the rapid cooling and hardening rate of the magnesium alloy material is much higher than in Examples 1 and 2, thus exhibiting an extremely fine structure.

[0062] Figure 8 The photo shows Mg made by the above method 0.67 Ca 0.33 The cross-section of the alloy observed under an optical microscope, while Figure 7 It shows the cross-section of the magnesium alloy material made by immersing the crucible in water and quenching under an optical microscope. Compare Figure 8 and Figure 7 it can be discovered Figure 8 The size of the composite phase (composition phase) in is extremely fine.

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Abstract

The present invention provides an implant consisting of a biodegradable magnesium-based alloy or partially applied with the magnesium-based alloy, and a method for manufacturing the same. The implant according to the present invention is biodegradable, in which its biodegradation rate can be easily controlled, and the implant has excellent strength and interfacial strength to an osseous tissue.

Description

[0001] The present invention is a divisional application of the original application number 200780035008.X, the filing date is September 21, 2007, and the title of the invention is "implant made of biodegradable metal and its manufacturing method" technical field [0002] The present invention relates to an implant and a method for its manufacture, in particular to an implant having biodegradable materials whose biodegradation rate can be easily controlled and whose strength is comparable to that of bone tissue The interface strength is extremely excellent, so it is used as a bone substitute or for bone therapy, and the present invention also relates to the manufacturing method of the implant. Background technique [0003] Typical implant materials for medical use are metal materials with excellent mechanical properties and processing performance. Although metal implants have excellent metallic properties, they still suffer from several problems, such as stress shielding, im...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/02A61L31/08A61L31/14A61L27/04A61L27/06A61L27/12A61L27/30A61K6/04
CPCA61F2/28A61F2002/30957A61F2/442A61F2/3662A61F2002/3631A61F2310/00041A61F2240/004A61F2/36A61L27/58A61F2/30767A61F2/06A61F2/3094A61L27/306A61B17/68A61F2310/00425A61B17/80A61L27/047A61F2210/0004A61F2002/30062A61F2310/00023A61F2240/001A61C8/0012A61F2002/30064Y10T428/31678A61C8/00
Inventor 梁硕祚石铉光金正九林泰弘白京昊金有灿具滋教
Owner U & I INC
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