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Compound amino acid multi-vitamin liquid micro-emulsion and preparation method thereof

A compound amino acid and liquid technology, which is applied in the field of compound amino acid and vitamin nutrition, can solve the problems of slow absorption of powdered medicines and drug effects, increase the labor intensity of breeding, and affect drug effects, etc., so as to quickly restore production performance and promote Growth effect, effect of improving disease resistance

Active Publication Date: 2012-01-18
RECOM QINGDAO BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For humans, there is no inconvenience in taking capsules, tablets or powders, but for livestock and poultry, especially large-scale breeding requires group administration (mixed drinking or mixed feeding) and it is very inconvenient. It is not only reflected in the preparation process, because the absorption and efficacy of powdered medicine are relatively slow, so in actual use, it needs to be artificially dissolved first and then added to the feed, which increases the labor intensity of feeding and increases the cost.
In addition, the active ingredients of the tablet or powder will be exposed to the air, which is prone to oxidative degradation and deterioration, affecting the efficacy of the medicine.

Method used

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  • Compound amino acid multi-vitamin liquid micro-emulsion and preparation method thereof
  • Compound amino acid multi-vitamin liquid micro-emulsion and preparation method thereof
  • Compound amino acid multi-vitamin liquid micro-emulsion and preparation method thereof

Examples

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Embodiment 1

[0027] Compound amino acid multidimensional liquid microemulsion, each 500mL liquid contains the following components:

[0028] Vitamin A 500000IU, Vitamin D3 100000IU, Vitamin E 3000mg with an active ingredient content of 50wt%, Vitamin C 10000mg, Vitamin B1 2500mg, Vitamin B2 4500mg, Vitamin K3 1000mg, Folic Acid 300mg, Calcium Pantothenate 2000mg, Niacin 5000mg, Serine 2200mg, Lysine Amino acid 5000mg, threonine 2000mg, tyrosine 400mg, cysteine ​​440mg, glutamine 720mg, methionine 3260mg, alanine 3400mg, phospholipid 345mL, cystin 150mg, immunoglobulin 450mg, polymyocyte 15mg, DHA 5mg, Taurine 20g, Xanthan Gum 20mL, Arabic Gum 10mL.

[0029] The preparation method of compound amino acid multidimensional liquid microemulsion (according to total volume is 500mL), comprises the following steps:

[0030] (1) dissolving fat-soluble components vitamin A, vitamin D3 and vitamin E in 345mL phospholipids to obtain component 1, the volume is 345mL;

[0031] (2) Water-soluble ingred...

Embodiment 2

[0037] Compound amino acid multidimensional liquid microemulsion, each 500mL liquid contains the following components:

[0038] Vitamin A 550000IU, Vitamin D3 100000IU, Vitamin E 3300mg with an active ingredient content of 50wt%, Vitamin C 10000mg, Vitamin B1 2500mg, Vitamin B2 4500mg, Vitamin K3 1000mg, Folic Acid 300mg, Calcium Pantothenate 2000mg, Niacin 5000mg, Serine 2200mg, Lysine Amino acid 5000mg, threonine 2000mg, tyrosine 400mg, cysteine ​​440mg, glutamine 720mg, methionine 3260mg, alanine 3400mg, phospholipid 390mL, cystin 150mg, immunoglobulin 450mg, polymyocyte 15mg, DHA 5mg, Taurine 20g, Xanthan Gum 20mL, Arabic Gum 10mL.

[0039] Bursalin is extracted through the following steps: Homogenate the bursa collected from healthy chickens, freeze and thaw three times at minus 20°C-36°C, freeze 16 hours and thaw for 8 hours each time, a cycle takes 24 hours in total, and then Centrifuge at 10,000 rpm for 30 minutes, and the supernatant is passed through an ultrafiltrat...

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Abstract

The invention relates to compound amino acid multi-vitamin liquid micro-emulsion, which comprises vitamin A, vitamin D3, vitamin E, vitamin C, vitamin B1, vitamin B2, vitamin K3, folic acid, calcium pantothenate, nicotinic acid, serine, lysine, threonine, tyrosine, cysteine, glutamine, methionine, lactamine, bursin, immune globulin, poly IC, docosahexaenoic acid (DHA) and taurine. A component 1 is obtained by dissolving fat soluble ingredients in phospholipid; a component 2 is obtained by dissolving aqueous soluble ingredients in purified water; the component 1 is homogenated to be added into the component 2 so as to obtain a mixture; a component 3 is obtained by mixing bursin, immune globulin and poly IC and by adding thermal stabilizing agent; and when the temperature of the mixture is decreased to 40 DEG C to 50 DEG C, the component 3, xanthan gum and Arabic gum are added into the mixture to be uniformly mixed. The compound amino acid multi-dimensional liquid micro-emulsion can be rapidly dissolved in the water, high-energy substances can be rapidly absorbed, and the bioavailability is high; the stable system guarantees the validity of the multiple vitamins, amino acid and the like during the storage period; and the cost performance is high.

Description

technical field [0001] The invention relates to the technical field of compound amino acid and vitamin nutrition products, in particular to a compound amino acid multidimensional liquid microemulsion, and also relates to a preparation method of the compound amino acid multidimensional liquid microemulsion. Background technique [0002] Compound amino acids and vitamins have always been used as nutrients, and are very popular among humans and livestock breeders. They can not only enhance people's physical fitness and immunity, but also have a good effect on improving the immunity and rapid growth of livestock and poultry. However, since some amino acids and vitamins are water-soluble and some are fat-soluble, it is difficult to mix components with different polarities and keep the system stable in preparation. In actual operation, It is often made into capsules or compressed into tablets, and excipients are added to make powders to keep the whole system stable. For humans, t...

Claims

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Application Information

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IPC IPC(8): A23K1/16A23K1/10A23K20/142A23K20/153A23K20/158A23K20/174A23K20/22A23K20/26
Inventor 骆延波刘玉庆白华齐静胡明朱小玲
Owner RECOM QINGDAO BIOTECH CO LTD
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