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Traditional Chinese medicinal dendrobium officinale preparation and preparation method thereof

A Dendrobium candidum preparation technology, which is applied in the field of traditional Chinese medicine Dendrobium candidum preparations and its preparation, can solve the problems of inconvenient consumption of Tiepi Fengdou, high viscosity of polysaccharide components, and inability to micronize, so as to save medicinal materials, reduce dosage, The effect of stable product quality

Inactive Publication Date: 2011-09-14
湖南龙石山铁皮石斛基地有限公司
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  • Application Information

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Problems solved by technology

[0004] Because the fresh products of Dendrobium candidum should not be stored for a long time, the existing Tiepi Fengdou is not very convenient to eat, especially most of the effective active ingredients it contains, such as polysaccharides, amino acids, vitamins, cellulose, trace elements and other organic substances, are mostly insoluble in Water or only slightly soluble in water, and a large number of polysaccharides in it are relatively viscous, and cannot be micronized by ordinary pulverization methods, resulting in a large amount of effective active ingredients that cannot be fully absorbed by the human body, resulting in a large waste

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  • Traditional Chinese medicinal dendrobium officinale preparation and preparation method thereof

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Embodiment 1

[0017] Example 1 Preparation Example

[0018] (1) Wash the fresh stem section of Dendrobium candidum, drain and set aside;

[0019] (2) Place the drained Dendrobium candidum in freeze-drying equipment, prefreeze at -35°C, drop from room temperature to -35°C, cool down for 2 hours, and keep the temperature constant for 3 hours when the temperature drops to -35°C;

[0020] (3) Sublimate and dry the Dendrobium officinale treated in step (2). First, evacuate to a vacuum degree of 30 Pa, and then heat and dry with the heating plate in the equipment. The temperature of the heating plate at the beginning is 20°C. The temperature was raised to 35°C, and the temperature was kept constant for 7 hours;

[0021] (4) Heat and evaporate the remaining water of the Dendrobium candidum that has been sublimated and dried in step (3), continue to heat up to 46°C, vacuum degree 20 Pa, heat up for 3 hours, and when the temperature reaches 46°C, dry at a constant temperature for 7 hours to Water ...

Embodiment 2

[0046] Embodiment 2 Clinical curative effect observation embodiment

[0047] In order to prove the advantages of the present invention, a preliminary observational study on the clinical curative effect of dendrobium candidum cell wall broken ultrafine powder on immunocompromised patients was carried out.

[0048] Randomized, single-blind controlled clinical research method. The experiment was divided into the same dose group of Dendrobium candidum ultrafine powder (equal dose with traditional decoction), 1 / 2 dose of Dendrobium ultrafine powder group (equal dose with traditional decoction) and traditional decoction group of Dendrobium candidum. The first two groups took the medicine by dissolving the ultra-fine powder of Dendrobium candidum in appropriate amount of warm water. The control group was decocted according to the traditional decoction and then concentrated to the same volume as the experimental group. The design completed the observation of 90 clinical cases.

[004...

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Abstract

The invention provides a traditional Chinese medicinal dendrobium officinale preparation and a preparation method thereof. In the preparation method, by adopting freeze-drying and ultra-fine pulverization methods, dendrobium officinale is frozen to a brittle point or below vitreous temperature so that the dendrobium officinale is in a brittle state, then the dendrobium officinale is dried and pulverized in mechanical and pneumatic modes so that cell walls are broken, and finally ultra-fine powder is obtained. The preparation method has the beneficial effects of increasing specific surface area of the preparation, improving dissolution rate and bioavailability of effective ingredients, increasing absorption rate and absorption capacity for human body, enhancing pharmacological action and improving medicament effect up to 3-10 times as that of the traditional dendrobium officinale decoction pieces, thus reducing medicament consumption and saving medicinal materials.

Description

technical field [0001] The invention relates to a traditional Chinese medicine dendrobium officinale preparation and a preparation method thereof. Background technique [0002] The precious and endangered medicinal material Dendrobium officinale ( Dendrobium officinale Kimura et Migo) are recorded in "Tao Zang", "Shen Nong's Materia Medica", "Compendium of Materia Medica", "Modern Chinese Medicine Dictionary", "The Pharmacopoeia of the People's Republic of China" and other medical classics, and the health care and treatment effects are definite. The Taoist classic "Tao Zang" in the first year of Tang Kai included nine Chinese immortal grasses (Dendrobium officinale, Tianshan snow lotus, Sanliang ginseng, 120-year-old Polygonum multiflorum, Poria cocos of the sixtieth year, Cistanche deserticola, Ganoderma lucidum, sea pearl, and Cordyceps sinensis). Dendrobium officinale has a remarkable effect of nourishing yin and tonifying deficiency, and is listed as the first of the "...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61P1/04A61P1/14A61P1/16A61P3/06A61P3/10A61P9/00A61P9/12A61P11/00A61P13/12A61P35/00A61P37/04A61P39/06
Inventor 赵兴兵张苏锋梁经军吴维佳
Owner 湖南龙石山铁皮石斛基地有限公司
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