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System and method for monitoring bioaerosol in real time

A bioaerosol, real-time monitoring technology, applied in biochemical equipment and methods, biomass post-treatment, biomass pre-treatment, etc.

Active Publication Date: 2011-09-07
北京鼎蓝科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, these studies are mainly aimed at the monitoring of microorganisms in liquid media, and there is no report on the use of silicon nanowire field-effect transistors to monitor bioaerosols online.

Method used

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  • System and method for monitoring bioaerosol in real time
  • System and method for monitoring bioaerosol in real time
  • System and method for monitoring bioaerosol in real time

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Experimental program
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Embodiment Construction

[0031] refer to figure 1 With the structure shown, the present invention realizes a specific system: the electrostatic field sampler 1 is connected to the biochip 3 through the sample delivery tube 2, and the microfluidic channel 4 is arranged on the biochip 3, on which a plurality of silicon nanowire biological Sensor 5 is also connected with signal preamplifier 6 and signal lock-in amplifier 7 on biochip 3 (signal preamplifier 6 and signal lock-in amplifier 7 are also connected), and signal lock-in amplifier 7 is equipped with computer LabView signal display Program 8 is used to display the monitoring results; the electrostatic field sampler 1 is connected to a peristaltic pump 9 through another sample delivery tube 2 to realize the real-time transmission of the sampling medium; the two ends of the peristaltic pump 9 are respectively connected to the sample collection bottle 10 and a sample liquid bottle 11; a vacuum pump 12 is connected to the base of the electrostatic fiel...

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Abstract

The invention discloses a system and method for monitoring bioaerosol in real time. The system comprises a sample acquisition and transmission unit, a signal detection and processing unit and a data output and display unit, wherein, the sample acquisition and delivery unit comprises a sampler (1), a sample delivery pipe (2), a peristaltic pump (5) and a sampling medium container; the signal detection and processing unit comprises a preamplifier (6), a phase-locked amplifier (7) and a biological chip (3) integrated with a biosensor (5); and the data output and display unit comprises a computerhost and a display connected with the phase-locked amplifier (7). The system and method provided by the invention can be used for monitoring infectious agents in the air, comprising viruses, bacteria, and allergen and the like in real time, can play a role in preventing the biological risks, such as large flu epidemic situation and bioterrorism activity and the like, and also can be used for dynamically representing the changes of microorganism in the air and the like.

Description

technical field [0001] The invention relates to a bioaerosol real-time monitoring system and method, which can be mainly used for real-time monitoring of pathogens (including viruses, bacteria, allergens, etc.) It can also be used to dynamically characterize changes in microorganisms in the air. Background technique [0002] Respiratory exposure to bioaerosols has caused many health problems. In recent years, large-scale influenza outbreaks such as SARS in 2003 and H1N1 influenza in 2009 have caused huge loss of life, property, and economy. In order to better prevent and resist these dangers, there is an urgent need for a technology that can monitor viruses and bacteria in the air in real time, but this has been a long-standing technical problem. In the past few years, many technologies have been tried to realize the online monitoring of bioaerosols, including mass spectrometry, surface-enhanced Raman technology, flow cytometry, and fluorescence-based Ultraviolet Aerodynami...

Claims

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Application Information

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IPC IPC(8): C12M1/34
Inventor 要茂盛朱彤申芳霞谭苗苗
Owner 北京鼎蓝科技有限公司
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