Whitening strip and preparation process thereof
A white patch, long-lasting technology, applied in cosmetic preparations, cosmetic preparations, preparations for skin care, etc., can solve the problems of insignificant effect, difficult to dull skin, dullness, and difficult to guarantee efficacy.
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Embodiment 1
[0012] Embodiment 1: Preparation of whitening patch
[0013] Preparation of cosmetic matrix: styrene-isoprene-styrene block copolymer (SIS) 1-70%, plasticizer 1-60%, tackifier 1-30%, antioxidant 0.1-3 %, react at a high temperature of 100-200°C for 0-5 hours to make a matrix material suitable for human skin. After cooling the glue block, set aside.
[0014] Preparation of functional ingredient raw material extract: First, weigh 1-5% arbutin crystals and grind them for use, then weigh 0.5-8% vitamin C derivatives, 0.1-3% licorice essence, and then take 0.01-2% Mulberry extract, 0.1-3% vitamin E acetate, 1-10% azone, 1-10% high-grade olive oil, etc. The above raw materials are mixed, stirred and evenly mixed. Stir the prepared raw material extract repeatedly for 10-20 minutes to make it fully mixed and set aside.
[0015] Preparation method: Put the cosmetic matrix and the functional ingredient raw material extract into the quantitative sol tank and the feeding tank respecti...
Embodiment 2
[0017] Embodiment two: arbutin transdermal absorbability comparison
[0018] The new whitening patch prepared in Example 1 was tested on isolated skin with the commercially available water-soluble patch and emulsion containing similar ingredients, and the experimental results were compared.
[0019] Test animals:
[0020] Adult mice (20g-25g) were killed, and the intact skin was peeled off (pre-depilated with 10% sodium sulfide for at least 48 hours), and the subcutaneous fat was removed.
[0021] experiment method:
[0022] The ex vivo skin was mounted on a Frans diffusion cell. The arbutin-containing test substances (new whitening patches, water-soluble patches, emulsions) were evenly spread on the skin, and the receiving fluid under the skin was collected 5 hours later, and the arbutin content was detected by HPLC.
[0023] test results:
[0024] The HPLC data analysis of the receiving solution through the Frans diffusion cell within 5 hours shows that with the prolonga...
Embodiment 3
[0026] The age of the test population:
[0027] Select 30 female volunteers aged 20, 30, and 40 and above.
[0028] Test plan:
[0029] Record personal information, create archives, divide by age group and instrument test, and then group and number, and give new whitening eye patches respectively. Observe with naked eyes, and take pictures to record the whitening effect before and after the test and record the phenomenon. Separately test and record each indicator, as well as the volunteers' feelings of use, and make a comprehensive evaluation.
[0030] Instructions:
[0031] According to the use method of the new whitening patch, remove the packaging, take it out, remove the protective layer, and gently stick the patch on the designated part of the tester. You can gently massage with your fingers to help the skin quickly absorb nutrients and achieve a whitening effect.
[0032] The use time is two weeks, use it after cleansing the skin every night, apply it to the designa...
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