Immunochromatographic test paper strip color signal quantitative detector

Abstract

The invention relates to an immunochromatographic test paper strip color signal quantitative detecting device, which comprises a lighting light source (1), a nontransparent shell (2), a transform lens (7), a slit (6), a photodetector (5), a primary amplification and alternating and direct (AD) control circuit (4) and a communication interface (3). By moving relative to a test paper strip along an axial direction of the test paper strip, the detector can quickly measure the detection line (T), quality control line (C) and light reflection strength of a back bottom part of the test paper strip. A connecting structure (8) is connected with different positioning accessories, so that the detector can adapt to detection of color signals of different package test paper strips. The detector has the characteristics of simple and compact structure, easy implementation, high sensitivity and low cost, and is convenient for multi-path integration or use in a handheld detection system.

Description

technical field [0001] This patent relates to a photoelectric detector for biochemical detection and quantification, in particular to an immunochromatographic detection test strip color depth detector based on the detection of localized reflected light intensity. Background technique [0002] In 1971, Faulk and Taytor introduced colloidal gold into the immunoassay method, forming the immunogold labeling technique (Immunogoldlabeling techique), which is to use colloidal gold as a tracer for antigen antibody labeling, and mainly use nitrocellulose membrane as a carrier to realize immunodetection. Colloidal gold immunochromatography assay (dot immunochromatography assay, DICA) uses the principle of capillary action to make the test solution chromatographically diffuse and realize the separation of the sample matrix, so the sample matrix has little interference and is widely used in the rapid diagnosis of diseases, health quarantine, Animal and plant quarantine, food safety test...

AI Technical Summary

Problems solved by technology

The advantage of using a photodiode or triode as a detector is low cost and simple control circuit, but it cannot distinguish the detection area from the surrounding background, so the detection reliability is poor; while using a CCD detector can effectively extract the measured range, but its control Complicated and costly, offsetting the low cost of test strips

In order to effectively improve the detection sensitivity and reliability of the photodiode or triode scheme, some of the prior art have adopted a light source focusing scheme, but the optical path of this scheme is relatively complicated. In order to obtain a small light spot, there must be high requirements for the light source, which increases the cost instead. , at the same time system integration, test strip alignment and other aspects have increased the difficulty

Images