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Traditional Chinese medicine composition for treatment of chronic diarrhoea and preparation method thereof

A kind of technology of chronic diarrhea, composition

Inactive Publication Date: 2011-05-25
津药达仁堂集团股份有限公司达仁堂制药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The preparation method of the drug is simple, and the curative effect is remarkable, but the dosage of the patient is relatively large, and the bioavailability needs to be improved

Method used

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  • Traditional Chinese medicine composition for treatment of chronic diarrhoea and preparation method thereof
  • Traditional Chinese medicine composition for treatment of chronic diarrhoea and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1: preparation of Chinese medicine extract

[0024] 1. Prescription:

[0025] Red stone fat (calcined) 500g, coptis 250g, cork 250g, myrobalan (pitted) 250g, nutmeg (simmered) 250g, magnolia officinalis (burned) 250g, Jianqu 250g, evodia (made) 200g, cinnamon 200g, dried ginger 250g, 200g of Zanthoxylum bungeanum, 200g of Chuanxiong, 200g of oyster (calcined), 250g of Gallnut, 250g of dark plum (pitted).

[0026] Two. Preparation method:

[0027] All raw materials were extracted twice with 12 times and 10 times of water, the first time was 6 hours, the second time was 2 hours, and the volatile oil was collected at the same time; the combined extracts were concentrated to a relative density of 1.05 at 50-60 ° C, and dried under reduced pressure; Spray into volatile oil, obtain extract powder 10g5g.

Embodiment 2

[0028] Embodiment 2: preparation of Chinese medicine extract

[0029] 1. Prescription:

[0030] Red stone fat (calcined) 500g, coptis 250g, cork 250g, myrobalan (pitted) 250g, nutmeg (simmered) 250g, magnolia officinalis (burned) 250g, Jianqu 250g, evodia (made) 200g, cinnamon 200g, dried ginger 250g, 200g of Zanthoxylum bungeanum, 200g of Chuanxiong, 200g of oyster (calcined), 250g of Gallnut, 250g of dark plum (pitted).

[0031] Two. Preparation method:

[0032] All raw materials were extracted twice with 14 times the amount and 12 times the amount of water, the first time was 6 hours, the second time was 4 hours, and the volatile oil was collected at the same time; the combined extracts were concentrated to a relative density of 1.03 at 50-60 ° C, and the pressure was reduced. Dry or spray dry; spray into volatile oil to obtain 960g of extract powder.

Embodiment 3

[0033] Embodiment 3: preparation of Chinese medicine extract

[0034] 1. Prescription:

[0035] Red stone fat (calcined) 500g, coptis 250g, cork 250g, myrobalan (pitted) 250g, nutmeg (simmered) 250g, magnolia officinalis (burned) 250g, Jianqu 250g, evodia (made) 200g, cinnamon 200g, dried ginger 250g, 200g of Zanthoxylum bungeanum, 200g of Chuanxiong, 200g of oyster (calcined), 250g of Gallnut, 250g of dark plum (pitted).

[0036] Two. Preparation method:

[0037] All the raw materials were extracted twice with 10 times the amount of water, each time for 4 hours, and the volatile oil was collected at the same time; the extracts were combined, concentrated to a relative density of 1.08 at 50-60°C, dried under reduced pressure or spray dried; sprayed into the volatile oil, obtained Cream powder 1100g.

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Abstract

The invention discloses a traditional Chinese medicine composition for the treatment of chronic diarrhoea and a preparation method thereof, belonging to the modernization field of traditional Chinese medicine. The active ingredients of the traditional Chinese medicine composition for the treatment of chronic diarrhoea are the following raw materials in parts by weight: 500 parts of halloysitum rubrum (forged), 250 parts of coptis root, 250 parts of phellodendron bark, 250 parts of myrobalan fruit (kernel removed), 250 parts of mace (stewed), 250 parts of magnolia bark (stir-baked), 250 parts of massa medicata fermentata, 200 parts of evodia rutaecarpa (prepared), 200 parts of cinnamon, 250 parts of rhizoma zingiberis, 200 parts of pericarpium zanthoxyli, 200 parts of chuanxiong rhizome, 200 parts of oyster (forged), 250 parts of gallnut and 250 parts of dark plum (kernel removed). By analyzing the prescription on the basis of the theory of traditional Chinese medicine, the preparation method of the traditional Chinese medicine composition containing reasonable and stable active ingredients is provided according to the research conclusion related to physicochemical properties and pharmacological actions of medicinal ingredients. The pharmaceutical preparation prepared according to the technical proposal has the advantages of stable and controllable quality, prominently enhanced therapeutic effect compared with current commercially-available dosage forms, lowered dosage for patients, improved bioavailability and remarkable economic and social benefits.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating chronic diarrhea and a preparation method thereof, belonging to the field of traditional Chinese medicine modernization. Background technique [0002] Chronic diarrhea, also known as chronic diarrhea, is a common clinical disease. Most patients with this disease have deficiency of qi in the spleen and stomach, relapse of seasonal evils, inappropriate diet, or depression of liver qi leading to repeated episodes of diarrhea. The clinical evidence of this disease is mostly the syndrome of deficiency and cold, and some also have evidence of damp heat. This type of diarrhea generally has a more acute onset, a shorter course of disease, and is easier to treat. Chronic diarrhea is chronic diarrhea. Chronic diarrhea is characterized by a long course of disease, difficult recovery, and easy recurrence, and its etiology and pathogenesis are more complicated. [0003] Guchang Cap...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P1/12A61K33/26A61K35/56A61K35/64A61K35/618
Inventor 李燕钰潘勤金兆祥肖锋王原张红茹
Owner 津药达仁堂集团股份有限公司达仁堂制药厂
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