Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

New liver and kidney nourishing decoction preparation (novel medicament delivery system) and preparation method thereof

A technology of preparations and pharmaceutical excipients, applied in the field of biomedicine, can solve problems such as inability to be absorbed and insufficient extraction of active ingredients, and achieve the effect of improving bioavailability

Inactive Publication Date: 2011-04-27
周艳
View PDF0 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] Traditional Chinese Yiguanjian preparations and various products developed in modern times are nothing more than decoctions (oral liquids), pills, or granules and tablets. To fully extract, at the same time, after oral administration, the maximum absorption cannot be obtained in the human body

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] prescription:

[0035] Radix Ginseng, Ophiopogon japonicus, Angelica, Rehmannia glutinosa, Lycium barbarum, Toosendan: 10g each;

[0036] Ethanol (75%): 10ML;

[0037] Honey: appropriate amount;

[0038] Purified water: 40ml.

[0039] Preparation:

[0040] Firstly, grind the cleaned and dried Adenophora, Ophiopogon japonicus, Angelica, Rehmannia glutinosa, Lycium barbarum, and Toosendan, and soak them in an appropriate amount of pure water for 8 hours. You can add an appropriate amount of ethanol when soaking;

[0041] In the second step, the soaked medicinal materials are extracted with microwave assistance, decocted at 50°C for about 60-100 minutes, and then filtered to collect the medicinal liquid for later use;

[0042] The third step is to concentrate the collected medicinal liquid to obtain a thick ointment for use;

[0043] The fourth step is to add ethanol and an appropriate amount of honey to the thick paste, dissolve and homogenize, filter, inspect the qu...

Embodiment 2

[0045] prescription:

[0046] Radix Ginseng, Ophiopogon japonicus, Angelica, Rehmannia glutinosa, Lycium barbarum, Toosendan: 10g, 10g, 10g, 30g, 12g, 5g respectively;

[0047] Coptis: 2.5g;

[0048] Ethanol: appropriate amount;

[0049] Polyethylene glycol: 6g

[0050] Soy lecithin: 1g

[0051] Polypropylene glycol: 0.1g;

[0052] Cholesterol: 0.5g.

[0053] Preparation:

[0054] Firstly, the cleaned and dried Adenophora, Ophiopogon japonicus, Angelica sinensis, Rehmannia glutinosa, Lycium barbarum, Toosendan, and Coptis chinensis are crushed, and soaked in an appropriate amount of 35% ethanol for 8 hours;

[0055] In the second step, the soaked medicinal materials are ultrasonically decocted at 65°C for about 100-120 minutes, and then filtered to collect the medicinal liquid for later use;

[0056] The third step is to concentrate and dry the collected medicinal liquid to obtain solid particles for use;

[0057] The fourth step is to heat and melt the polyethylene gl...

Embodiment 3

[0059] prescription:

[0060] Radix Ginseng, Ophiopogon japonicus, Angelica, Rehmannia glutinosa, Lycium barbarum, Toosendan: 25g each;

[0061] Ethanol: appropriate amount;

[0062] Refined honey: appropriate amount.

[0063] Preparation:

[0064] Firstly, crush the cleaned and dried Adenophora, Ophiopogon japonicus, Angelica, Rehmannia glutinosa, Lycium barbarum, and Toosendan, then add an appropriate amount of ethanol and 6 times the amount of water to soak for 8 hours;

[0065] In the second step, the soaked medicinal materials are refluxed and decocted at 100°C for about 4-8 hours, and then filtered to collect the medicinal liquid for later use;

[0066] The third step is to concentrate the collected medicinal liquid to obtain a thick ointment for later use;

[0067] The fourth step is to heat and melt the refined honey first, then add the above-mentioned thick paste while it is still hot, stir evenly, cool, inspect, and fill it.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a new liver and kidney nourishing decoction preparation (a novel medicament delivery system) for treating hepatitis and a preparation method thereof, which belong to the field of biomedicine. The new preparation comprises six medicinal materials, namely coastal glehnia root, dwarf lilyturf tuber, Chinese angelica, rehmannia root, barbary wolfberry fruit and szechwan Chinaberry fruit, and a proper amount of extract of a coptis component serving as main raw materials, and is prepared by the following steps of: extracting and separating; properly adding medicinal auxiliary materials; and finally preparing by the conventional process of formulations such as sprays, ointments (or syrups), pills, aerosols, dispersible tablets, orally disintegrating tablets, targeting preparations, controlled release preparations and the like. Through improved technology, the curative effect of the conventional compound prescription is further improved, so the technical requirement of controllable quality of the modern Chinese traditional medicine is met, the side effect is also reduced, and the compliance of a clinical medicament is improved. The new preparation has the unique effects of treating difficult and complicated diseases such as the hepatitis, hepatocirrhosis, liver cancer, gastritis, pregnancy-induced hypertension syndrome, tubal ligation syndrome, herpes zoster, central retinitis, recurrent aphtha, other gynecological diseases and the like, so that the new preparation has unique clinical application value.

Description

technical field [0001] The invention relates to a new Yiguanjian preparation (new drug delivery system) (new drug delivery system) for treating hepatitis and a preparation method thereof, belonging to the field of biomedicine. Background technique [0002] The modernization of traditional Chinese medicine and the research and development of traditional Chinese medicine varieties occupy a very important strategic position in the layout of my country's pharmaceutical industry. Modern dosage forms will become the focus of new drug research and development and old product transformation. [0003] In recent years, the research and development of new dosage forms of traditional Chinese medicine has been extremely rapid. With the continuous progress of the pharmaceutical industry and the development of new drugs, the level of traditional Chinese medicine preparations in my country has gradually risen from the traditional empirical type to the level of scientific pharmaceuticals. Th...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/8968A61K9/12A61K9/06A61K9/20A61K9/00A61P1/16A61P1/04A61P35/00A61P15/00A61P9/12A61P31/22A61P9/10A61P1/02
Inventor 周艳陈峰刘亚欢高建义王登之王海涛柴韦
Owner 周艳
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com