Manufacture method of prosthesis with self-antibacterial action

Abstract

The invention relates to a manufacture method of a prosthesis with a self-antibacterial action, belonging to the technical cross field of advanced manufacture and tissue engineering. The method comprises the steps of: establishing a three-dimensional model by adopting CT or MRI image data of a patient; designing internal and surface pore structures; manufacturing a wax mould and a resin mould through rapid forming and combining with a premise casting method to obtain a metal prosthesis; or obtaining the metal prosthesis through a laser or electronic beam rapid manufacture method or digital control processing method; and processing a polished surface and injecting or depositing surface silver ions to obtain the prosthesis with the self-antibacterial action. The prosthesis has individuation and elastic modulus close to the natural bone of a human body, and is suitable for cell growth, antibiosis and inflammation diminishing, and the like, greatly lightens the pain of the patient, and improves the life quality of the patient. The method is especially suitable for the individualized manufacture, self-antibacterial treatment and clinical application of the prosthesis.

Description

technical field [0001] The invention relates to a method for manufacturing an artificial prosthesis with self-antibacterial effect, which belongs to the cross field of advanced manufacturing and tissue engineering technology. Background technique [0002] With the increasing aging of the world population and the increasing number of people injured due to participation in strenuous sports, the demand for artificial implants, especially artificial joints, is increasing. According to incomplete statistics, there are 40 to 60 million people in the world who need joint replacement due to various diseases, and the current annual joint replacement is about 1.2 million cases, which is far from the actual demand. It is estimated that there are more than 300,000 joint replacement patients in my country every year, but the actual annual replacement is less than 30,000 cases. At present, its main materials are divided into metal materials, ceramic materials and polymer materials. Amon...

AI Technical Summary

Problems solved by technology

[0004] The traditional manufacturing method of artificial prosthesis represented by titanium and titanium alloy has the following problems: (1) The artificial prosthesis manufactured by lost foam casting, forging and machining has a long production cycle, and only a few fixed-sized implants can be manufactured. implants for patients to choose, if the manufacture of implants based on the patient's individuality will result in huge workload and cost, can not provide personalized medical services for patients; (2) metal artificial prosthesis such as titanium and titanium alloy The internal structure is simple, and the elastic modulus is 4 to 10 times that of human natural bone, which is prone to "stress shielding", resulting in loosening of the implant, resulting in surgical failure and reducing the service life of the artificial prosthesis

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