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Wound-covering hydrogel material

A coating material, hydrogel technology, used in medical science, bandages, absorbent pads, etc., can solve problems such as insufficient adhesion, and achieve the effect of preventing skin irritation, preventing wet environment, and protecting excellent

Active Publication Date: 2011-01-26
TEIKOKU SEIYAKU KK TEIKOKU SEIYAKU CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, in order to impart adhesive force to PVA hydrogel, it has been proposed to perform treatment such as radiation irradiation (see Patent Document 4), but the adhesive force is not sufficient.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Dissolve carboxyvinyl polymer in an appropriate amount of pure water (1.6g), then add D-sorbitol solution (20g), and mix well. Then with polyacrylic acid (0.3g), tartaric acid (1.2g), concentrated glycerin (20.7g), sodium carboxymethylcellulose (3.5g), polyacrylic acid partially neutralized (4g), anhydrous silicic acid (0.1g ), castor oil (1.5g), aluminum dihydroxyglycinate (0.07g), sodium edetate (0.08g) and pure water (appropriate amount) were uniformly mixed to prepare a hydrogel. The hydrogel was stretched on urethane (20 μm) / nylon elastomer (25 g / m 2 ), the surface of the gel was covered with a polyester film, thereby producing a hydrogel wound dressing material.

Embodiment 2

[0049] Using the ingredients of Example 2 described in Table 1, a hydrogel was prepared in the same manner as in Example 1, stretched on urethane (20 μm) / nylon tricot fabric (support), and coated with polyester The membrane coats the gel surface, thereby producing a hydrogel wound dressing material.

Embodiment 3

[0051] Dissolve anhydrous silicic acid (0.5g) in an appropriate amount of pure water, then add urea (1.0g), sodium edetate (0.08g), and castor oil (0.5g), and mix well. Then 20% polyacrylic acid aqueous solution (15.0g), tartaric acid (0.3g), concentrated glycerin (16.0g), sodium carboxymethylcellulose (4.0g), polyacrylic acid partially neutralized (5.0g), aluminosilicate Magnesium aluminum metasilicate (0.06 g), dry aluminum hydroxide gel (0.02 g) and an appropriate amount of pure water were uniformly mixed to prepare a hydrogel. The hydrogel was stretched on urethane (20 μm) / nylon elastomer (25 g / m 2 ), the surface of the gel was covered with a polyester film, thereby producing a hydrogel wound dressing material.

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PUM

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Abstract

A wound-covering hydrogel material which has excellent stretchability and absorbs exudates from wounds. It can maintain over long a wet environment which is suitable for accelerating the healing of wounds. There is no fear of causing pain or damaging the regenerated skin when the wound-covering hydrogel material is replaced with a fresh one. The wound-covering hydrogel material comprises: a laminated two-layer film composed of a polyurethane film and hydrophobic fibers; and a hydrogel spread on the laminated film, the hydrogel comprising a water-soluble (semi)synthetic polymer, glycerol, and water. The covering material has a moisture permeability as measured by the cup method in accordance with JIS Z0208 of 500-2,000 (g / m2 / 24h).

Description

technical field [0001] The present invention relates to a hydrogel wound dressing material. The hydrogel wound dressing material has excellent stretchability, absorbs the exudate from the wound surface, can maintain a moist environment suitable for promoting wound surface healing for a long time, and can be used when the wound is replaced. The covering material does not cause pain or damage the regenerated skin. Background technique [0002] Conventionally, gauze, powder, spray, ointment, emulsion, sponge, etc. have been used as therapeutic agents for wound surfaces. Most of these therapeutic agents heal the wound by absorbing the exudate from the wound surface to dry the wound site. However, in recent years, it has been clarified that maintaining a moderately moist environment by maintaining exudate on the wound surface is more effective in promoting wound healing than drying the wound site, and it has been recognized that maintaining the wound site in a moderately moist e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/16
CPCA61L15/16A61L15/26A61L15/60C08L75/04
Inventor 镰仓高志佐藤亚纪高桥诚大浦武彦
Owner TEIKOKU SEIYAKU KK TEIKOKU SEIYAKU CO LTD
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