Swine health granules and preparation process thereof

Abstract

The invention discloses swine health granules, which are granules prepared by using gentian, atraotydin, bupleurum, dried ginger, sodium bicarbonate, starch, sucrose powder as raw materials, wherein the granules comprise no less than 2.0 percent by weight of gentiopicrin, no less than 0.05 percent by weight of atractylenolide III and no less than 11.0 percent by weight of sodium bicarbonate. A preparation process of the swine health granules comprises the following step of: extracting gentian by using ethanol; carrying out steam distillation on atraotydin and bupleurum to extract essential oil of atraotydin and bupleurum; carrying out water extraction on dried ginger, sodium bicarbonate, gentian dregs obtained by ethanol extraction and atraotydin and bupleurum dregs obtained after the essential oil is extracted; mixing water extract with ethanol extract of gentian, which is obtained after ethanol is recovered, and aqueous solution obtained after atraotydin and bupleurum are distilled; after the mixture is subjected to ethanol precipitation treatment, concentrating the obtained product into a fluid extract; uniformly mixing the fluid extract with starch and sucrose powder and preparing granules from the mixture; and finally spraying the essential oil of atraotydin and bupleurum on the surfaces of the granules to obtain the swine health granules. The swine health granules of the invention represent an improvement of the preparation form of the conventional veterinary medicament, namely the swine health powder. The effect experiment shows that the curative effect of the swine health granules is obviously superior to that of the swine health powder.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, in particular to a pig health granule and a preparation process of the granule. Background technique [0002] In veterinary clinics, the digestive system diseases of pigs, sheep, cattle, horses, dogs and other animals account for about 30% of the total clinical incidence, while symptoms such as loss of appetite, indigestion, constipation, abdominal distension, rumen food accumulation, and gastrointestinal relaxation are almost Concomitant or secondary to most diseases in animals. For the treatment of such symptoms, cholinergic Western medicines such as carbachol and neostigmine are often used, but they are highly toxic and have strong effects. Traditional Chinese veterinary medicine has rich experience in the treatment of gastrointestinal dysfunction, and the source of Chinese veterinary medicine is rich and has few side effects. The use of Chinese veterinary medicine in the treatment ...

AI Technical Summary

Problems solved by technology

But it has the following problems: (1) The specific surface area increases after the medicinal material is pulverized, and the irritation, hygroscopicity and chemical activity etc. also increase correspondingly, it is easy to mold and deteriorate, and some volatile components are easy to lose; (2) The medicinal material after pulverization Directly applied to animals, the active ingredients dissolve slowly, oral absorption is incomplete, bioavailability is low, and the onset of action is slow; (3) Zhujian powder has a strong taste and bitter taste, and the palatability is not good. When livestock and poultry are sick, it is necessary to mix the medicine with concentrate There will also be less food or no food, and the dosage cannot be guaranteed

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