Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

BC febrifugal refreshment paste for auxiliary treatment of fever and emergent physical hypothermia and preparation thereof

A technology of physical cooling and adjuvant therapy, applied in the direction of microorganism-based methods, antipyretics, biochemical equipment and methods, etc., can solve the problem that the antipyretic Xingnao patch has no obvious antipyretic effect, and bacterial cellulose-based antipyretics have not yet been seen. Heat refreshment paste, take away skin heat and other problems, to achieve good application prospects, easy to operate, soft and light texture effect

Active Publication Date: 2010-09-29
DONGHUA UNIV
View PDF3 Cites 14 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after testing, it was found that the antipyretic effect of this antipyretic Xingnao patch is not obvious. The polymer gel layer contains very little free water, which cannot take away the heat of the skin through the evaporation of water. the cooling sensation
At present, there are no reports on the research and development of bacterial cellulose-based antipyretic Xinnao patch for auxiliary treatment of fever and emergency physical cooling at home and abroad.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • BC febrifugal refreshment paste for auxiliary treatment of fever and emergent physical hypothermia and preparation thereof
  • BC febrifugal refreshment paste for auxiliary treatment of fever and emergent physical hypothermia and preparation thereof
  • BC febrifugal refreshment paste for auxiliary treatment of fever and emergent physical hypothermia and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] 1. Preparation and treatment of BC membrane

[0038]Acetobacter xylinum (Acetobacter xylinum) was expanded and cultivated in the seed medium at 30°C for 24 hours according to the inoculation amount of 2 to 3 inoculation loops, and then transferred to the fermentation medium according to the inoculum amount of 6% at 30°C for static culture respectively 4, 7,10 days, harvest bacterial cellulose (BC) wet film; The prepared BC film is soaked in 1% NaOH solution in 80 ℃ of water baths until BC film turns white and translucent, then the BC film that makes and commercially available Antipyretic patches were cut into rectangles with a diameter of 2cm×4.5cm for later use, among which the thickness of BC_4d was 1.61mm, the thickness of BC_7d was 2.78mm, the thickness of BC_10d was 3.44mm, and the thickness of commercially available antipyretic patches was 2.50mm;

[0039] Among them, the seed medium and the fermentation medium are: mannitol, glucose, sucrose or fructose 2.5g, pep...

Embodiment 2

[0048] 1. Preparation and treatment of BC membrane

[0049] Gluconacetobacter xylinus was cultured in the seed medium at 30°C for 24 hours according to the inoculum amount of 2-3 inoculation loops, and then transferred to the fermentation medium at 6% inoculum amount for static culture at 30°C. 4,7,10 days, harvest bacterial cellulose (BC) wet film; Prepared BC film is soaked in 2% NaOH solution in 90 ℃ of water baths until BC film becomes white and translucent, then the BC film that makes is mixed with Commercially available antipyretic patches are cut into rectangles with a diameter of 2cm×4.5cm for later use, among which the thickness of BC_4d is 1.62mm, the thickness of BC_7d is 2.74mm, the thickness of BC_10d is 3.47mm, and the thickness of commercially available antipyretic patches is 2.50mm ;

[0050] Among them, both the seed medium and the fermentation medium are: mannitol, glucose, sucrose or fructose 10g, yeast extract 0.5g, peptone 0.5g, citric acid 0.115g, Na 2 ...

Embodiment 3

[0059] 1. Preparation and treatment of BC membrane

[0060] Gluconobacter xylinum was expanded and cultivated in the seed medium at 30°C for 24 hours according to the inoculation amount of 2 to 3 inoculation loops, and then transferred to the fermentation medium at 30°C according to the inoculum amount of 6% for static culture respectively 4, 7,10 days, harvest bacterial cellulose (BC) wet film; The prepared BC film is soaked in 0.5% NaOH solution in 100 ℃ of water baths until the BC film turns white and translucent, then the prepared BC film is compared with commercially available The antipyretic patch is cut into a rectangle with a diameter of 2cm×4.5cm for later use. The thickness of BC_4d is 1.64mm, the thickness of BC_7d is 2.68mm, the thickness of BC_10d is 3.38mm, and the thickness of commercially available antipyretic patch is 2.50mm;

[0061] Among them, both the seed medium and the fermentation medium are: mannitol, glucose, sucrose or fructose 2g, yeast extract 0.5g...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a BC febrifugal refreshment paste for auxiliary treatment of fever and emergent physical hypothermia and preparation thereof. The BC febrifugal refreshment paste comprises the components: a bacterial cellulose membrane and febrifugal refreshment medicinal reagent. The preparation comprises the following steps of: performing seed culture on BC production strains at the temperature of 30 DEG C, inoculating the BC production strains to a fermentation culture medium for culture to prepare a BC wet membrane, then immersing the wet membrane into NaOH solution, and performing water bath until the BC membrane is white and semitransparent and putting the BC membrane aside for later use; and then putting the BC membrane into heat-clearing refreshment medicinal liquid to process the BC membrane for 5 to 30 minutes to prepare the febrifugal refreshment paste. The bacteria cellulose-based febrifugal refreshment paste has the advantages of high moisture content, good biocompatibility, no conglutination and stimulation to skin, safety and environmental protection; and the preparation method has the advantages of simplicity, convenience, easy operation, low cost and friendliness to environment, and has the excellent application prospect.

Description

technical field [0001] The invention belongs to the field of antipyretic xingnao plaster and its preparation in biomedical materials, and particularly relates to a BC antipyretic xingnao plaster for auxiliary treatment of fever and emergency physical cooling and its preparation. Background technique [0002] Bacterial Cellulose (BC) is a kind of natural cellulose synthesized by microorganisms. From the molecular formula, BC is no different from ordinary plant cellulose, but because of its unique physical and chemical structure, it endows it with extremely high mechanical strength and biocompatibility. The formed BC is composed of ribbon-shaped microfibers, which are highly crystalline and highly single-oriented fibers, which are intricately entangled together to form a unique three-dimensional network structure. There are many "holes" inside the unique three-dimensional network structure of BC, which has good air permeability, Water permeability, can absorb 60 to 700 times ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/752A61K36/61A61K31/045A61K31/085A61K36/185A61K36/233A61K36/534A61K36/54A61K31/125A61K31/11A61K31/717A61K9/70A61P29/00A61P25/00C12P19/04C12R1/01C12R1/02C12R1/41C12R1/38C12R1/025C12R1/05C12R1/065
CPCY02A50/30
Inventor 洪枫魏斌杨光
Owner DONGHUA UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com