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Needleless powder injection medicament administration device

An injection device and needle-free powder technology, which is applied in the direction of hypodermic injection equipment, etc., can solve the problems of air pressure reduction in gas cylinders, affect the total air flow and injection speed, and poor air tightness, so as to prevent the failure of injection ability and prolong the validity period of use , The effect of improving injection safety

Inactive Publication Date: 2012-02-01
THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] (1) Poor air tightness: Since the piston columnar valve runs through the entire gas storage cylinder and performs controlled release, it will definitely affect the air tightness of the gas storage cylinder: the gas storage cylinder is a gas with a relatively high pressure, and the piston The columnar valve is a valve with convenient precession, and the gas can easily escape from the tiny gap between the piston valve body and the piston barrel, which will reduce the air pressure of the gas storage bottle and affect the total amount of air flow and injection speed during use;
[0007] (2) The dose is unstable and the drug delivery efficiency is low: when the piston is pushed, the high-pressure gas first enters the secondary air chamber, and after a certain pressure is accumulated, it presses the pressure-bearing film on the upper end of the drug-carrying box and pushes it into the drug box. powder injection
Since it is difficult to ensure that the process of pushing the piston is consistent each time, and because the secondary air chamber will generate a partial pressure, which will cause the pressure of the entire system to drop, it is impossible to guarantee the amount of gas entering the secondary air chamber each time the drug is administered, which eventually leads to The gas flow rate is different each time the drug is administered, and the injection effect is also different, making it difficult to reproduce a stable dosage
At the same time, due to the existence of the secondary air chamber, the drug delivery efficiency of this design is also low;
[0008] (3) The controlled release mechanism lacks safety: the push rod of the piston is located at the end of the device, in a position that is easily excited. This device is not designed with a safety bolt to protect the push rod from accidental activation. , sales and other processes are subject to external impact and failure
[0011] (1) Injection safety issues: Since the gas storage cylinder needs to be broken to realize the deflation process during use, the damaged part of the gas storage cylinder will inevitably produce some extremely fine particle debris during the process, and the gas will carry These debris flow together and will eventually be injected into the human body together with the drug powder, causing harm to the human body;
[0012] (2) Control accuracy problem: Since the throat of the gas cylinder will be punctured by the sharp end each time, it is difficult to ensure that the position of each puncture is consistent with the size of the punctured space, so the accuracy of each administration cannot be guaranteed. accuracy;
[0013] (3) High production cost: this design uses an irreversible destruction method to realize the escape of gas, and the gas storage cylinder can only be disposable, which will increase production and use costs

Method used

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  • Needleless powder injection medicament administration device
  • Needleless powder injection medicament administration device
  • Needleless powder injection medicament administration device

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Embodiment Construction

[0029] Such as figure 1 , 2 As shown, the present invention is composed of four major structures such as a gas storage bottle 1, a controlled release mechanism 2, a drug-carrying box 3 and an air flow nozzle 4. The structure of the present invention will be further described in detail below.

[0030] Such as figure 1 , 2 As shown, the gas storage bottle 1, the controlled release mechanism 2, the drug-carrying box 3 and the air flow nozzle 4 are arranged in sequence. The key of the present invention lies in the improvement to controlled release structure 2, as figure 1 , 2 As shown, what the controlled-release mechanism 2 adopts is a ball valve mechanism, and the ball valve mechanism further includes: a valve body 21 connecting the gas storage bottle 1 and the drug-carrying box 3, and a valve body 21 is provided on the valve body 21 to make the gas storage bottle 1 and the drug-carrying box 3 The spool 22 that is turned on or off, and the valve body 21 is also provided wi...

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Abstract

The invention discloses a needleless powder injection medicament administration device. The device comprises an air bottle, a controlled release mechanism, a medicament-carrying box and an airflow spraying tube, which are connected in sequence, wherein the controlled release mechanism is a ball valve mechanism; and the ball valve mechanism further comprises a valve body connected with the air bottle and the medicament-carrying box, the valve body is provided with a valve core used for connecting or disconnecting the air bottle and the medicament-carrying box, and the valve body is also provided with an elastic mechanism driving the valve core to rotate. Compared with the conventional piston column-shaped valve, the device has the advantages that: the ball valve mechanism has higher air tightness, so that the air tightness of the whole system is greatly improved, the injection failure caused by air leakage can be avoided to the maximum extent, and the service life of an injector is prolonged; and because the valve core of the ball valve mechanism is big in diameter and air-discharging quantity, the air-discharging process can be completed in the shortest time, and the air-discharging effect of the ball valve mechanism is far better than that of the piston column-shaped valve.

Description

technical field [0001] The invention relates to a needle-free powder injection drug delivery device. Background technique [0002] Needle-free powder injection mainly uses high-speed gas jets to deliver drugs to intradermal, subcutaneous or mucosal parts. It is a bioengineering drug such as proteins, peptides, vaccines, etc. that are unstable to acids and enzymes. The device can be widely used in patients with needle fear or patients who need long-term self-administration, as well as medical prevention in major emergencies (earthquakes, floods, wars) and prevention and treatment of major acute infectious diseases. Medical insurance under conditions such as regional and large-scale field operations. [0003] The existing needle-free powder injection drug delivery device mainly uses high-pressure gas to accelerate the drug powder, so that the drug powder reaches a very high speed (such as 600-1000m / s), and the high-speed powder penetrates the stratum corneum of the skin to r...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M5/303
Inventor 王伽伯肖小河王喆桅金城
Owner THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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