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Radioactive particle chain connected by controllable and fast degradable magnesium and magnesium alloy

A technology of radioactive particles and rapid degradation, applied in the field of medical devices, can solve the problems of uneven particle dose distribution, affecting the overall curative effect of clinical radioactive particles in brachytherapy, and difficulty in maintaining the distance between particles in a straight line, achieving uniform distribution and excellent Mechanical properties, effect of good compatibility

Inactive Publication Date: 2010-08-18
张福君 +1
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, in the actual operation of particle implantation, it is often difficult to maintain the linear arrangement of particles and the distance between particles, which makes the particle dose distribution uneven and affects the overall curative effect of clinical radioactive particle brachytherapy.

Method used

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  • Radioactive particle chain connected by controllable and fast degradable magnesium and magnesium alloy
  • Radioactive particle chain connected by controllable and fast degradable magnesium and magnesium alloy
  • Radioactive particle chain connected by controllable and fast degradable magnesium and magnesium alloy

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Embodiment Construction

[0027] Taking the most commonly used 6711 iodine-125 particles in clinical practice as an example, its sealed shell is a miniature titanium tube with a diameter of 0.8 mm and a length of 4.5 mm (such as figure 2 shown). Clean the titanium tube sealed with radionuclide and the magnesium or magnesium alloy wire with a diameter of ≤0.8mm and a length of 5mm, and polish the surface of the magnesium and magnesium alloy wire with metallographic sandpaper. Iodine-125 particles ( figure 1 -②) and magnesium and magnesium alloy wire ( figure 1 -①) Welded end to end to form a radioactive particle chain of a certain length. The length of the particle chain depends on the number of particles. Particle chains of a certain length can be made in batches in advance, and intercepted according to needs before surgery, or particle chains of various lengths can be made according to the treatment plan. During the operation, the prepared particle chains are loaded into a matching implant gun, an...

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Abstract

The invention discloses a radioactive particle chain connected by controllable and fast degradable magnesium and a magnesium alloy and belongs to the field of medical devices implanted in bodies. The radioactive particle chain with certain length is prepared by connecting the controllable and fast degradable magnesium, the magnesium alloy 1 and radioactive particles 2 through welding at certain distances. The radioactive particles have the therapeutical effect, and the magnesium and the magnesium alloy are used as connecting materials, so that the radioactive particle chain comprises unique controllable and fast degradation characteristics. The radioactive particle chain has the functions of ensuring uniform distribution of the particles, preventing the particles wandering, and reducing distances among the particles with reduction of tumors and making the particles uniformly distributed on focuses all the time when the particle chain is degraded after being implanted for 1 to 2 months. The radioactive particle chain is suitable for curing extensive diseases such as intracranial tumors, nasopharyngeal carcinoma, oropharyngeal carcinoma, tongue cancer, cervical metastatic tumors, lung cancer, breast cancer, pancreatic cancer, cholangiocarcinoma, liver cancer, prostate cancer, gynecological tumors, and soft tissue and bone tumors.

Description

technical field [0001] The invention belongs to the field of medical equipment implanted in a body, and in particular relates to a controllable and rapidly degradable magnesium and a radioactive particle chain connected by magnesium alloy. Background technique [0002] Interstitial implantation of radioactive seeds for treating malignant tumors is a design scheme using computerized stereotaxic planning system (TPS). Under the guidance of modern medical imaging, radioactive particles are implanted into the tumor or infiltrated by the tumor in a minimally invasive way according to the size and shape of the tumor. In the invaded tissue, the continuous and short-distance radiation is emitted by the micro-radiation source, so that the tumor tissue is killed to the greatest extent, while the normal tissue is not damaged or only slightly damaged, and finally achieves the purpose of treating the tumor. Because particle implantation therapy has the characteristics of less trauma, hig...

Claims

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Application Information

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IPC IPC(8): A61M36/12
Inventor 张福君段光峰
Owner 张福君
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