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Method for detecting Jingan capsule

A detection method and capsule technology are applied in the directions of capsule delivery, measuring device, pharmaceutical formulation, etc., which can solve the problems of insufficient control of product quality and insufficient detection method of acetaminophen content, improve the level of quality monitoring, and be beneficial to product quality. the effect of monitoring

Active Publication Date: 2010-08-11
GUIZHOU BAILING GRP PARMACEUTIAL CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the existing quality standard of Jingan Capsules, the content detection methods of honeysuckle, dandelion, and amantadine hydrochloride are not included, and the content detection methods of acetaminophen are also insufficient, so the control of product quality is insufficient

Method used

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  • Method for detecting Jingan capsule
  • Method for detecting Jingan capsule
  • Method for detecting Jingan capsule

Examples

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Embodiment

[0138] A method for detecting a capsule for the treatment of colds. According to parts by weight, the capsule is prepared with 250g of honeysuckle, 250g of Andrographis paniculata, 250g of Radix Radix, 250g of dandelion, 250g of paracetamol, 50g of amantadine hydrochloride and chlorobenzene maleate. Namin 1.0g is prepared into 1000 capsules; it is characterized in that, the detection method comprises the following steps:

[0139] Properties: This product is a capsule, the contents are brownish yellow to brown granules and powder; slight gas, bitter taste;

[0140] Identification: (1) Take 1g of the content of this product, grind it finely, moisten it with water, add 20ml of ethyl acetate, ultrasonicate for 5 minutes, discard the ethyl acetate solution, and repeat the same method for the residue from "adding 20ml of ethyl acetate" Once, add 5 drops of 1mol / L hydrochloric acid solution to the residue, add 20ml of ethyl acetate, ultrasonicate for 5 minutes, take the ethyl acetate...

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Abstract

The invention discloses a method for detecting a capsule for treating cold. The capsule is prepared from honeysuckle, common andrographis herb, isatis root, dandelion, acetaminophen, amantadinehydrochloride and chlorphenamine maleate. The invention increases the content detection of the amantadinehydrochloride, the honeysuckle and the dandelion on the basis of the traditional quality standard, improves a content detecting method of the acetaminophen, can carry out more effective control on main medicament components of a Jingan capsule, and enables the quality monitoring level of the Jingan capsule to be greatly improved. The application of the invention is more beneficial to manufacturers and the supervisory management department to monitor the product quality and can provide better guarantee for the medical department and the treatment of patients.

Description

technical field [0001] The invention relates to a detection method of capsules, in particular to a detection method of capsules (common name or drug name Jingan Capsule) used for treating colds, and belongs to the technical field of pharmacy. Background technique [0002] Jingan Capsule is a popular product in the market. It has the effect of clearing away heat and detoxifying, dispelling wind and relieving the surface. It can be used for influenza, exogenous wind-heat syndrome, and can treat symptoms such as headache, nasal congestion, runny nose, cough and sore throat. . The honeysuckle, andrographis paniculata, dandelion, acetaminophen and amantadine hydrochloride in the formula of Jingan capsules are the characteristic index components of Jingan capsules. The existing quality standards for Jingan Capsules do not include methods for detecting the content of honeysuckle, dandelion, and amantadine hydrochloride, and the method for detecting the content of acetaminophen is ...

Claims

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Application Information

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IPC IPC(8): A61K36/35A61K9/48A61P11/00G01N30/90G01N30/02A61K31/167A61K31/13A61K31/4402
Inventor 李星安斯扬夏文吴春玲
Owner GUIZHOU BAILING GRP PARMACEUTIAL CO LTD
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