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Preparation method of Bawei Chenxiang capsule

The technology of Bawei agarwood and capsules is applied in the field of preparation of Bawei agarwood capsules, which can solve the problems of poor drug stability, inconvenience in taking, inconvenient to carry, etc., and achieves the effects of being convenient to take, easy to carry, and scientific and reasonable in production technology

Inactive Publication Date: 2009-12-02
INNER MONGOLIA MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this powder dosage is big, and the bad smell that medicine has simultaneously makes taking inconvenient, carries inconvenient simultaneously
Because the prescription contains bovine heart, the stability of the drug is relatively poor

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Example 1: The preparation method of Bawei Chenxiang capsules includes the following steps: (1), extract volatile oil, (2), alcohol extraction, (3), make beef heart into freeze-dried powder, (4), water extraction process , (5), prepared into a capsule dosage form; where

[0016] (1) Extract volatile oil: extract volatile oil by steam distillation, take 250g of nutmeg, 250g of clove, 250g of woody and 250g of Asafoetida, add 250g of nutmeg, 250g of clove, 250g of woody and 250g of Asafoetida. Soak in water for 2 hours, reflux for 4 hours, and extract the volatile oil; the volatile oil is wrapped with β-cyclodextrin, by weight of volatile oil: β-cyclodextrin is 1:3, the inclusion temperature is 40℃, and the inclusion time is 2 hours , Prepare β-cyclodextrin inclusion compound;

[0017] (2) Alcohol extraction: Put 250g of Chinese jujube, 250g of Inula vulgaris and 250g of agarwood into 50% ethanol, of which 7500g of ethanol, reflux and extract once, each reflux time of 1.5 hou...

Embodiment 2

[0021] Example 2: The preparation method of Bawei Chenxiang capsules includes the following steps: (1), extract volatile oil, (2), alcohol extraction, (3), make beef heart into freeze-dried powder, (4), water extraction process , (5), prepared into a capsule dosage form; where

[0022] (1) Extract volatile oil: extract volatile oil by steam distillation, take 250g nutmeg, 250g clove, 250g woody and 250g of Asafoetida, add 250g nutmeg, 250g clove, 250g woody and 250g Asafoetida total 12000g Soak in water for 6 hours and reflux for 8 hours to extract the volatile oil; the volatile oil is wrapped with β-cyclodextrin, by weight, the volatile oil: β-cyclodextrin is 1:5, the inclusion temperature is 60°C, and the inclusion time It is 6 hours to prepare β-cyclodextrin inclusion compound;

[0023] (2) Alcohol extraction: Put 250g of Chinese jujube, 250g of Inula vulgaris and 250g of agarwood into 70% ethanol, where ethanol is 10500g, and extract 3 times under reflux for 2.5 hours each tim...

Embodiment 3

[0027] Example 3: The preparation method of Bawei Chenxiang capsules includes the following steps: (1), extract volatile oil, (2), alcohol extraction, (3), make beef heart into freeze-dried powder, (4), water extraction process , (5), prepared into a capsule dosage form; where

[0028] (1) Extract volatile oil: extract volatile oil by steam distillation, take 250g of nutmeg, 250g of clove, 250g of woody and 250g of asafoetida, add 1000g of water, soak for 4 hours, reflux for 6 hours, extract volatile oil; use β-ring for volatile oil Dextrin package, in parts by weight, of which volatile oil: β-cyclodextrin is 1:4, the inclusion temperature is 50°C, and the inclusion time is 4 hours, to prepare β-cyclodextrin inclusion compound;

[0029] (2) Alcohol extraction: Put 250g of Chinese jujube, 250g of Inula vulgare and 250g of agarwood into 60% ethanol, where ethanol is 9000g, and extract twice with reflux time for 2 hours each time to obtain a thick paste ;

[0030] (3). The beef heart...

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Abstract

The invention discloses a preparation method of a Bawei Chenxiang capsule, which comprises the following steps: (1) extracting volatile oil; (2) carrying out alcohol extraction; (3) preparing ox-hearts into freeze-dried powder; (4) carrying out a water extraction process; and (5) preparing a capsule dosage form. The invention has the advantages that the preparation method is scientific and reasonable, integrates modern separation and extraction technologies and extracts related effective components and positions of all medicines according to indication functions so that the efficacy of the medicines is fully applied and the Bawei Chenxiang capsule can achieve the efficacy of the powder of the original prescription with the half dosage of the powder of the original prescription. The capsule preparation avoids the bad odor of medicines and is conveniently taken and carried. After the capsule preparation is changed into capsules, the stability of the medicines is improved.

Description

Technical field [0001] The invention relates to a method for preparing medicines, in particular to a method for preparing Bawei Chenxiang capsules. Background technique [0002] The original prescription of the Bawei Chenxiang capsule of the present invention is a powder, which is contained in the folk prescription "Puji Prescriptions". The original Bawei Chenxiang powder is composed of 250g agarwood, 250g wood incense, 250g clove, 250g jujube, and Xuanfuhua A compound preparation consisting of 250g, 250g asafoetida, 250g nutmeg, and 150g beef heart. The dosage is 3 grams each time, 2 times a day. It has the effects of calming qi and blood, relieving pain, and replenishing the heart and qi. It is used to treat heart pain, fainting, palpitations, insomnia, restlessness, amnesia, epilepsy and other diseases. However, the dosage of the powder is large, and the medicine has a bad smell, which makes it inconvenient to take and to carry. Because the prescription contains bovine heart, ...

Claims

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Application Information

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IPC IPC(8): A61K36/835A61K9/48A61K47/40A61P25/08A61P9/00A61P25/20A61P29/00A61K35/34
Inventor 王玉华宋宏春王伟俞腾飞杨丽敏
Owner INNER MONGOLIA MEDICAL COLLEGE
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