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Cordyceps and ganoderma lucidum polysaccharides compound preparation with immune synergism

A technology of Ganoderma lucidum polysaccharide and compound preparation, which is applied in the field of medicine, can solve the problems that the active ingredients cannot be fully utilized, and achieve the effects of improving cellular immunity and humoral immunity, obvious immune synergy, and increasing NK cell killing activity

Inactive Publication Date: 2009-10-21
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention discloses a compound preparation of Cordyceps sinensis and Ganoderma lucidum polysaccharide with immune synergistic effect, which is a preparation made of active ingredients separated from Cordyceps sinensis, Ganoderma lucidum mycelium or fruiting bodies, and solves the problem of the direct The problem that its active ingredients cannot be fully utilized when used as medicine

Method used

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  • Cordyceps and ganoderma lucidum polysaccharides compound preparation with immune synergism
  • Cordyceps and ganoderma lucidum polysaccharides compound preparation with immune synergism
  • Cordyceps and ganoderma lucidum polysaccharides compound preparation with immune synergism

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Experimental program
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Effect test

Embodiment 1

[0073] Weigh 10 g of Cordyceps fungus powder and Ganoderma lucidum fungus powder respectively into a 500ml Erlenmeyer flask with a solid-to-liquid ratio of 1:30, add 300ml of distilled water, and bathe in 90°C water bath for 3 hours. Centrifuge to get the supernatant, and rotate every 300ml of extract to 20ml, then add 4 times of 95% ethanol, shake, and keep overnight at 4°C. Take the precipitate and centrifuge at 4°C, 5500r / min, 10min. Remove the precipitate, dry it, and grind it into a powder with a mortar. The obtained Cordyceps polysaccharide powder and Ganoderma lucidum polysaccharide powder.

Embodiment 2

[0075] Weigh 10 g of Cordyceps fungus powder and Ganoderma lucidum fungus powder respectively into a 500ml Erlenmeyer flask with a solid-to-liquid ratio of 1:30, add 300ml of distilled water, and bathe in 90°C water bath for 3 hours. Centrifuge to get the supernatant, and rotate every 300ml of extract to 20ml, then add 4 times of 95% ethanol, shake, and keep overnight at 4°C. Take the precipitate and centrifuge at 4°C, 5500r / min, 10min. Remove the precipitate, dry it, and grind it into a powder with a mortar. The obtained Cordyceps polysaccharide powder and Ganoderma lucidum polysaccharide powder.

Embodiment 3

[0077] Preparation of Compound Tablets of Cordyceps and Ganoderma lucidum Polysaccharides

[0078] Prescription: make 0.4g of Cordyceps polysaccharide powder and 0.1g of Ganoderma lucidum polysaccharide powder into a polysaccharide compound preparation, 0.5g in total, starch 86.5g, gelatin 6.0g, sodium carboxymethyl cellulose, 5.0g, magnesium stearate 1.0g, talcum powder 1.0g made into 200 tablets.

[0079] Preparation method: Take 0.4g of Cordyceps polysaccharide powder, 0.1g of Ganoderma lucidum polysaccharide powder, 86.5g of filler calcium sulfate, 6g of wetting agent and binder including gelatin, 5g of sodium carboxymethyl cellulose according to the prescription, and add water to make a soft material , pass through a 20-mesh sieve to granulate, dry at 60°C, granulate through a 20-mesh sieve, add the prescribed amount of lubricant and glidant, mix well, adjust the appropriate pressure and press into tablets to obtain the compound preparation tablet of Cordyceps and Ganoder...

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Abstract

The invention provides a cordyceps and ganoderma lucidum polysaccharides compound preparation with immune synergism, which is a compound preparation consisting of polysaccharides from cordyceps and ganoderma lucidum polysaccharides. Dosage forms prepared from the polysaccharides compound have the immunoregulation function, can obviously improve the activity of NK cells, the phagocytic activity of macrophage of organisms, and cellular immunity and humoral immunity functions of the organisms, and have immunoregulation function on the organisms. The cordyceps and ganoderma lucidum polysaccharides compound preparation solves the problem that active ingredients cannot take effect fully because cordyceps, and mycelium or encarpium of ganoderma are directly used as medicaments.

Description

technical field [0001] The invention provides a compound preparation of Cordyceps sinensis and Ganoderma lucidum polysaccharide with immune synergistic effect. The combination of the two substances has obvious immune synergistic effect and belongs to the technical field of medicine. technical background [0002] Cordyceps militaris (Cordyceps militaris) in the present invention is a kind of fungus that grows on the pupal body, and is identified as Ascomycotina (Ascomyeotina), Clariceptaceae (Clariceptaceae), Cordyceps (Cordyceps) plant. According to reports, Cordyceps militaris fermented liquid has good therapeutic effects on asthma and bronchial diseases, immune regulation, and enhancement of renal function in patients with renal failure. Scholars at home and abroad have systematically studied its chemical composition and physiological activity. Polysaccharides are one of the important active components of Cordyceps militaris, including adenosine and mannitol. [0003] Gan...

Claims

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Application Information

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IPC IPC(8): A61K31/736A61K31/715A61P37/02A23L1/30A23L33/10A23L33/105
Inventor 孟庆繁滕利荣逯家辉谢晶刘杨刘磊王贞佐高朝辉孟令军程瑛琨
Owner JILIN UNIV
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