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Improved prescription of Xianchan tablet medicament and preparation method thereof

A technology of Xianchan Tablets and medicines, which is applied in the field of improved Xianchan Tablet drug prescription and its preparation, and can solve problems such as elevated blood pressure

Active Publication Date: 2009-07-08
SHAANXI DONGKE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Xianchan Tablet has the functions of regulating qi and nourishing the kidney, resolving phlegm and softening hardness, eliminating phlegm and removing dampness, clearing the menstrual flow and removing blood stasis, detoxifying and removing dampness, dispelling cold and relieving pain, promoting blood stasis and dredging collaterals, nourishing the kidney and resolving hardness, eliminating turbidity and benefiting the kidney, attacking poison and fighting cancer, Supporting sores and promoting granulation, strengthening the body and eliminating pathogens, clearing toxins and expelling toxins, regulating qi and blood, and regulating the spleen and stomach. It has been proved by pharmacodynamics, toxicology, and clinical trials that it has a good effect on the treatment of cancer tumors, but in the course of use It was found that some patients had some side effects such as vomiting, increased blood pressure, and shortness of breath after taking it, so it is very necessary to adjust or improve the prescription of the original drug

Method used

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  • Improved prescription of Xianchan tablet medicament and preparation method thereof
  • Improved prescription of Xianchan tablet medicament and preparation method thereof
  • Improved prescription of Xianchan tablet medicament and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039]Take each raw material according to the following parts by weight:

[0040] Nuxychnium powder 40 parts, toad 0.5 part, psoralen 100 parts, pinellia (made) 40 parts, turmeric 40 parts, ginseng 20 parts, astragalus 10 parts, angelica 10 parts, Agrimony 40 parts.

[0041] Preparation:

[0042] Take nuxya powder, ginseng, toad venom, pinellia (made), turmeric, astragalus, angelica, agrimony and select them separately, wash them, and process them. Parts are dried and crushed into fine powder, passed through a 100-mesh sieve, mixed thoroughly, and set aside.

[0043] Grind the remaining 20 parts of psoralen into coarse powder and mix it with nuxychonna powder, add 6 times the amount of 70% ethanol and soak for 48 hours, infiltrate at a speed of 3 ml per minute, collect the initial percolation, and continue percolation until effective The ingredients are completely filtered out, the first and second ethanol are combined, filtered, ethanol is recovered from the filtrate to obt...

Embodiment 2

[0048] Weigh each component raw material according to the following parts by weight: 60 parts of Nuxychee powder, 1.5 parts of toad venom, 200 parts of psoralen, 60 parts of pinellia (made), 60 parts of turmeric, 40 parts of ginseng, 30 parts of astragalus, Angelica 30 parts, Agrimony 60 parts.

[0049] Preparation method: Nuxychnium seed powder, ginseng, toad venom, pinellia (made), turmeric, astragalus, angelica, agrimony are selected separately, washed, processed, 160 parts of psoralen and 1.5 parts of toad venom, Pinellia (made ) 60 parts were dried and pulverized into fine powder, passed through a 100-mesh sieve, mixed thoroughly, and set aside. Use a high-efficiency extraction and concentration unit to crush the remaining 40 parts of psoraleae into coarse powder and mix it with nuxychonnia powder, add 5 times the amount of 65% ethanol and soak for 45 hours, permeate at a speed of 3 milliliters per minute, collect the initial liquid, Filtrate, and recover the ethanol fro...

Embodiment 3

[0052] Weigh each component raw material according to the following parts by weight: 50 parts of nuxychnium powder, 1 part of toad venom, 165 parts of psoralen, 50 parts of pinellia (made), 50 parts of turmeric, 30 parts of ginseng, 20 parts of astragalus, Angelica 20 parts, Agrimony 50 parts.

[0053] Preparation method: Nuxychnium seed powder, ginseng, toad venom, pinellia (made), turmeric, astragalus, angelica, Agrimony are selected separately, washed, processed, 130 parts of psoralen and toad venom, pinellia (made) are dried Finally, crush it into fine powder, pass through a 100-mesh sieve, mix thoroughly, and set aside. Grind the remaining 35 parts of psoralen into coarse powder and mix it with Nuxychnium seed powder, add 7 times the amount of 75% ethanol to soak for 55 hours, infiltrate at a speed of 3 ml per minute, collect the initial liquid, filter, and recover the filtrate Ethanol is used to clear the ointment and set aside. Use a high-efficiency extraction and con...

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Abstract

The invention discloses an improved tablet medicament with hairy vein agrimony and arenobufagin. The medicament comprises the following raw material drugs as active components by weight part: 40 to 60 parts of nuxvomica poison nut seed powder, 0.5 to 1.5 parts of the arenobufagin, 100 to 200 parts of psoralea, 40 to 60 parts of pinellia tuber, 40 to 60 parts of turmeric, 20 to 40 parts of ginseng, 10 to 30 parts of hoantchy root, 10 to 30 parts of angelica, and 40 to 60 parts of the hairy vein agrimony. Simultaneously, the invention improves a process for preparing the original tablet with the hairy vein agrimony and the arenobufagin; compared with the prior tablet with the hairy vein agrimony and the arenobufagin, the process reduces dosage of the arenobufagin, proves that the improvement is successful with the anti-cancer effect unreduced through three-batch trial production and research of arenobufagin content measurement methodology and determination of content limit by using the three batches of samples.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine preparation prepared from traditional Chinese medicines, in particular to an improved medicine prescription of Xianchan tablets and a preparation method thereof. Background technique [0002] "Cancer" is called a malignant tumor in modern medicine, and it is the cruelest killer that threatens human life and health in the world. Once infected, very few survived the death. [0003] Traditional Chinese medicine believes that there are several causes of cancer: emotional depression, worry, anger, phlegm turbidity, and liver disorder, which makes the liver prosperous and qi stagnation, phlegm turbidity accumulates, and qi stagnation and phlegm turbidity follow the meridians. Chi internal injury, liver-qi inversion, endogenous phlegm turbidity, stagnation of qi and phlegm turbidity, stagnation of qi and blood, blood stasis with qi stagnation, lo...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/00A61K9/06A61K9/14A61K9/20A61P35/00A61K35/56A61K35/65
Inventor 赵东科
Owner SHAANXI DONGKE PHARMA
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