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Compound Chinese medicine preparation for treating yellow-white dysentery of piglet

A technology of piglet yellow and white scour and compound traditional Chinese medicine, which is applied in the direction of medical preparations containing active ingredients, antibacterial drugs, drug combinations, etc., can solve the problems of E. coli drug resistance, economic loss, etc., and achieve high cure rate and quick effect Effect

Inactive Publication Date: 2009-07-01
CHONGQING FANGTONG ANIMAL PHARMA
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AI Technical Summary

Problems solved by technology

There are many varieties of antibacterial drugs for the treatment of colibacillosis in piglets on the market. Due to frequent dressing changes in clinical treatment and random increase in drug dosage, long-term use of a single species can easily induce drug resistance in E. coli, thus encountering The problem of ineffective prevention and control has brought serious economic losses to production

Method used

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  • Compound Chinese medicine preparation for treating yellow-white dysentery of piglet

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Experimental program
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Effect test

Embodiment 1

[0008] Embodiment 1: the in vitro bacteriostatic test of preparation of the present invention

[0009] According to the introduction in the literature, the test was carried out by the tube-and-disk method. Draw the prepared bacterial solution (the bacterial content is 9.85×10 8 / ml) 0.25ml, on the nutrient agar plate, spread evenly with a sterile L-shaped glass rod, place 3 sterilized Oxford cups equidistantly on this agar plate, add the liquid medicine (concentration is 225.0mg / ml) respectively ml), marked with a mark, cultivated at 37°C for 24 hours, observed and measured the diameter of the inhibition zone. The results are shown in Table 1. The MIC was determined by the agar double dilution method, and the results are shown in Table 2.

[0010] Table 1 Antibacterial test results

[0011]

[0012] As can be seen from Table 1, Golden Root Injection is effective against Escherichia coli O at 225.0 mg / ml. 8 K 88ac , Salmonella SO 3 C 78 , Staphylococcus aureus CMCC (...

Embodiment 2

[0018] Embodiment 2: the clinical curative effect test of preparation of the present invention

[0019] Test method: 120 Rongchang pigs with similar parity, age, and litter size were selected and randomly divided into 4 groups, 30 pigs in each group. C group), middle dose group (D group), high dose group (E group), select 30 healthy piglets with similar age and parity simultaneously as healthy controls (group A), and the administration dose of Andrographis paniculata injection is 5ml per head, the dosages of Jingen injection low, medium and high dose groups were 1, 2, 4ml / head respectively, intramuscular injection, 2 times a day, 3 days as a course of treatment.

[0020] During the test period, observe the clinical performance and physiological indicators of the test animals, such as mental state, appetite, feces, body temperature, respiration, pulse, etc., and record them in detail, and observe them for 7 days after a course of treatment.

[0021] Criteria for judging clinic...

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Abstract

The invention discloses a composite traditional Chinese medicine - Jingen injection for treating piglet yellow and white dysentery. The traditional Chinese medicine is formed by extracting and separating the effective ingredients from honeysuckle and isatis root using the modern traditional Chinese medicine extraction technique and is a pure natural green veterinary medicine capable of clearing away the heat-evil and expelling superficial evils with antibiotic and anti-inflammatory effect. The Jingen injection is used for treating livestock and poultry diarrhea, dysentery, etc. due to E. coli, Salmonella, Clostridium perfringens infection, especially for piglet yellow and white dysentery. The composite traditional Chinese medicine has features of convenient use, obvious curative effect and stable quality, without drug resistance, medicine residue and side effect.

Description

technical field [0001] The invention relates to the clinical application of a compound traditional Chinese medicine preparation for treating yellow and white scours of piglets, and belongs to the field of traditional Chinese veterinary medicine products for preventing and treating livestock and poultry diseases. Background technique [0002] Piglet colibacillosis is a general term for a class of piglet infectious diseases caused by pathogenic Escherichia coli. Due to the different types of pathogenic Escherichia coli and the differences in pig growth period, physiological function and immune status, colibacillosis in piglets is often divided into four types: yellow scour of piglets, pullorum of piglets, diarrhea of ​​weaned piglets and edema of piglets. Piglet yellow scour mainly occurs in newborn piglets within 1 week of age. It is a common infectious disease of newborn piglets. Clinically, it is characterized by yellow watery feces and rapid death. Piglet pullorum is a no...

Claims

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Application Information

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IPC IPC(8): A61K36/35A61P1/12A61P31/04
Inventor 吴俊伟姜永康姜波宋小红邓开锋刘昌林饶勇
Owner CHONGQING FANGTONG ANIMAL PHARMA
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