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Biology collagen brown medical soft suture-thread manufacture method

A manufacturing method and suture technology, which are applied in the fields of medical science, surgery, surgical instruments, etc., can solve the problems of large dragging trauma of human tissue, hard thread body, easy to hide foreign bodies, etc., and achieve high tensile strength and knotting strength. The needle thread connection is smooth and the biocompatibility is good.

Active Publication Date: 2012-05-23
SHANDONG BODA MEDICAL PROD CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The imported absorbable chemically synthesized suture (PGA) used in contemporary clinical operations is a multi-strand braided structure, which has certain defects: foreign objects and dead bacteria are easy to hide in the gaps of the thread structure, and the surface is rough, which greatly damages human tissues.
The chemical substances and ethylene oxide residues in the line body have potential side effects that affect the recovery of patients; the chemical synthesis line has a short shelf life, strict storage environment requirements, and high storage risk
Since the 1980s, bioabsorbable sutures have been widely used clinically. The threads are hard, knotted unstable, and knots are easy to slide. Inflammation is likely to occur during the period, which directly affects the quality of the operation and increases the pain of the patient; ordinary suture needles are connected by punching presses, slotted thread-covering needles, and the tails of the needles are prone to produce flat mouths, ovals, ribs and other irregular shapes. Rough, large drag trauma to human tissue

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] The preparation method of this embodiment is as follows (the following concentrations are all weight percent concentrations):

[0011] Firstly, fresh green goat casings, cattle casings or collagen fibers in cartilage are selected. Clean the inner wall of fresh casings that have been quarantined and disease-free, and the mucosa, serosa, and mesentery in the casings are roughly scraped, processed, and delaminated, and the bulking agent NaHCO 3 Perform loosening treatment; in order to separate and remove the fat in smooth muscle fibers and collagen fibers, a unique process is adopted: in 3% sodium bicarbonate solution (because the body produces a lot of acid during metabolism, so sodium bicarbonate plays an important role in buffering blood pH Therefore, the compatibility between blood and materials is good), adding 6% lipase triacylglycerol acyl hydrolase and 2% food emulsifier fatty acid glyceride at a temperature of 30°C and a pH value of 7 for degreasing treatment, wit...

Embodiment 2

[0013] The preparation method of this embodiment is as follows (the following concentrations are all weight percent concentrations):

[0014] First, choose fresh green goat casings, yellow cattle casings or cartilage collagen fibers that have been quarantined and disease-free to wash the inner wall, and then scrape and delaminate the mucous membrane, serosa, and mesentery in the casing, and use the leavening agent NH4HCO3 Loosening treatment: add 6% sodium tripolyphosphate and 2% food emulsifier sucrose ester to 5% sodium bicarbonate solution, degrease at a temperature of 35°C and a pH value of 10, use 75% ethanol solution, Put in 3% anhydrous sodium bisulfite for antisepsis and sterilization, bleach and soak for 2-3 hours to eliminate harmful substances in the fibers, then soak with medical glycerin for 1 hour and then wash with soft water to clean the collagen fibers, The smooth muscle fibers are then processed by a special automatic fine scraping machine to squeeze out the ...

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PUM

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Abstract

The invention discloses a method for manufacturing a medical apparatus, in particular to a method for manufacturing a soft brown biological collagen medical suture. The method for manufacturing the soft brown biological collagen medical suture is characterized by comprising the following steps: firstly, washing the inner wall of a fresh intestine and casing which has no disease after quarantine to be clean, performing coarse scrapping processing and delamination treatment on mucous membranes, serous membranes and mesenteries in the intestine and casing, and using a raising agent to perform loosening treatment; secondly, separating and cutting off fats in smooth muscle fibers and collagen fibers; thirdly, adding pyro into softened water, soaking fiber materials into the softened water for washing, and performing polymerization processing and setting treatment; and fourthly, using an automatic coreless grinding machine to perform processing and polishing, and performing suture and needle connection. The soft brown biological collagen medical suture has soft line body, easy operation, good positioning performance, high tensile strength and knotting strength and smooth suture-needle connection, reduces inflammation reaction during wound healing, and achieves perfect combination of the suture and a stitching needle.

Description

(1) Technical field [0001] The invention relates to a method for manufacturing a medical device, in particular to a method for manufacturing a biocollagen brown medical soft suture. (2) Background technology [0002] At present, the quality of absorbable medical sutures widely used in clinical practice is directly related to the recovery of postoperative patients and marks the level of manufacturing technology in the field of contemporary medical devices. The imported absorbable chemically synthesized suture (PGA) used in contemporary clinical operations is a multi-strand braided structure, which has certain defects: foreign objects and dead bacteria are easy to hide in the gaps of the thread structure, and the surface is rough, which greatly damages human tissues. . The chemical substances and ethylene oxide residues in the line body have potential side effects that affect the recovery of patients; the chemical synthesis line has a short shelf life, strict storage environm...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L17/08
Inventor 张建林张玉福
Owner SHANDONG BODA MEDICAL PROD CO LTD
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