Preparation method of spleen byproducts for producing homology anti-serum blood and transfer factor from fox, raccoon dog, mink

Abstract

The invention relates to a preparation method for obtaining blood used for preparing homologous antiserums and a spleen byproduct used for preparing transfer factors from the bodies of fur bearing animals such as foxes, raccoon dogs and minks; the furs of the foxes, the raccoon dogs and the minks are taken concentratedly in December and confirmed according to the fur-taking dates of different areas; healthy individuals are picked up 45 days before a predicated fur-taking date; the booster immunization of univalent vaccines or polyvalent vaccines of canine distemper, Canine parvovirus enteritis, adenovirus disease, corona virus laxness, parainfluenza, and pasteurellosis is carried out for 3 times by purified and condensed antigens on the foundation of carrying out immunization for once in summer; when the furs are taken, aseptic anticoagulation blood collection is carried out to a heart to improve the blood serum yield; and the spleens of the animals are collected for extracting specific or common transfer factors simultaneously. The blood can be conveniently prepared into the blood serums which resist communicable diseases, and the transfer factors can be extracted the spleen, thus providing guarantee for the healthy development of the breeding in the next year; the invention is used for curing the corresponding communicable diseases of the wild animals of the same species; and when a small amount of communicable disease cases appear in a breeding crowd, the corresponding pathogeny hyper-immune serums and transfer factors are mainly injected to a supposed healthy crowd after the pathogeny is confirmed so as to cure the affected animals in the early period of disease and control the spreading of the epidemic situations.

Description

Technical field: [0001] The present invention relates to a method for preparing homologous antiserum and transfer factor of foxes, raccoon dogs and minks, in particular to a method for preparing anti-infectious disease serum from fur animal foxes, raccoon dogs and minks simultaneously and using The preparation method of the spleen for the preparation of the transfer factor is used to prepare low-cost homologous antiserum and the raw material of the transfer factor. Background technique [0002] Fur animals such as foxes, raccoon dogs, and mink are prone to infectious diseases in high-density breeding, especially canine distemper, parvovirus enteritis, adenovirus disease, coronavirus diarrhea, parainfluenza, and pasteurellosis, which are highly contagious and have a high fatality rate. The animal breeding industry is seriously harmful; the antiserum produced by the body caused by viruses and germs is a special medicine for the early treatment of the corresponding disease; the...

AI Technical Summary

Problems solved by technology

However, the antiserum for emergency use of fur animals has always been based on the antiserum of xenogeneic animals (such as dogs, sheep, donkeys, rabbits, etc.), and the antisera of xenogeneic animals are prone to allergic reactions to heterologous components in serum, and the xenogeneic animals used to prepare antiserum High feeding costs; currently the same species of animals are rarely used to prepare antiserum, and the existing preparation method - only by taking a small amount of venous blood from healthy old animals for emergency treatment, the preparation cost of better relative dog antiserum is relatively high